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Drug & Alcohol Rehab Centers in Harrisburg, Pennsylvania

Find verified addiction treatment facilities in Harrisburg. Our directory includes 5 licensed rehabilitation centers offering detox, residential, outpatient, and specialty programs. Most facilities accept insurance.

Updated: December 19, 2025
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Genesis House Inc
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Genesis House Inc

2505 North Front Street, 17110
570-419-0467

Located in Harrisburg, PA, Genesis House Inc specializes in offering a wide range of substance use treatment programs for those on the path to recovery. The center features various options including intensive outpatient treatment, outpatient services, and outpatient day treatment, also known as partial hospitalization. With a strong emphasis on 12-step facilitation, anger management, and brief intervention techniques, this facility customizes treatment plans to cater to the unique needs of adolescents, adult men, and adult women. Genesis House Inc is dedicated to providing quality care and personalized support for adults, children, adolescents, and young adults of all genders, striving to help clients achieve sustainable recovery. If you or someone you care about is in need of addiction treatment, this center offers a compassionate and effective route to healing.

Substance use treatment
Harrisburg Comprehensive Treatment Ctr
+9 photos

Harrisburg Comprehensive Treatment Ctr

Discovery House HA LLC

3601 North Progress Avenue, 17110
717-233-7290

Situated in Harrisburg, PA, the Harrisburg Comprehensive Treatment Center is dedicated to providing specialized outpatient programs for substance use treatment. The facility offers a range of services, including outpatient treatments with methadone, buprenorphine, or naltrexone. In addition to this, clients can access regular outpatient treatment and benefit from various therapeutic methods such as anger management, brief interventions, and cognitive behavioral therapy. What sets this center apart is its commitment to serving a wide array of individuals. They offer specialized programs designed for adult men and women, as well as the LGBTQ community. By catering to both adults and young adults, the Harrisburg Comprehensive Treatment Center strives to deliver high-quality care and support for anyone looking to embark on their journey toward effective rehabilitation.

Substance use treatment
Ponessa Behavioral Health
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Ponessa Behavioral Health

900 North 6th Street, 17102
717-233-4027

Ponessa Behavioral Health, situated in Harrisburg, PA, specializes in outpatient substance use treatment catering to both adults and children who are grappling with serious co-occurring mental health challenges. The center is committed to offering tailored care through various methods, including brief intervention, cognitive behavioral therapy, and motivational interviewing. Focused on the specific needs of different groups, Ponessa serves active duty military personnel as well as adult men and women, ensuring each program is designed with their unique circumstances in mind. The facility prioritizes high-quality care and provides outpatient treatment options such as methadone/buprenorphine or naltrexone, alongside general outpatient services. With a dedication to serving clients of all genders and various age groups, Ponessa Behavioral Health aims to deliver comprehensive and effective rehabilitation solutions.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Pennsylvania Psychiatric Institute
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Pennsylvania Psychiatric Institute

Advancement in Recovery Program

2501 North 3rd Street, 17110
717-782-6844

Located in Harrisburg, PA, the Pennsylvania Psychiatric Institute offers a variety of specialized treatment options for those dealing with substance use and co-occurring mental health disorders. The center features intensive outpatient programs, along with outpatient services that include methadone/buprenorphine or naltrexone treatments. Emphasizing techniques such as anger management, brief intervention, and cognitive behavioral therapy, the facility serves adult men and women, in addition to children and adolescents. For individuals who have faced trauma, the center provides specialized programs to meet their unique needs. The Pennsylvania Psychiatric Institute is dedicated to delivering quality care to anyone seeking customized support for mental health and substance use challenges.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Evergreen House of Catholic Charities - Placeholder

Evergreen House of Catholic Charities

120 Willow Road, 17109
717-412-4594

Evergreen House of Catholic Charities, located in Harrisburg, PA, provides dedicated substance use treatment and transitional housing for adult women who have faced intimate partner violence, domestic violence, or sexual abuse. This facility features long-term residential programs that emphasize 12-step facilitation, anger management, and brief intervention strategies. Specifically designed for adult women, including both seniors and young adults, Evergreen House offers a secure and nurturing environment conducive to recovery. With a focus on quality care and personalized treatment, it stands out as a compassionate option for individuals looking to find their way to healing and sobriety.

Substance use treatmentTransitional housing, halfway house, or sober home

Addiction Treatment in Harrisburg, Pennsylvania

Harrisburg offers specialized addiction treatment options, from medical detox to long-term residential care. Whether you're seeking help for yourself or a loved one,Harrisburg's treatment centers provide professional, compassionate care with various program types and payment options.

Why Choose Treatment in Harrisburg?
  • Specialized treatment centers with various programs
  • Licensed facilities with experienced professionals
  • Local recovery community and support groups
  • Full continuum of care from detox to aftercare
  • Centers of Excellence integrated care model
  • Access to Penn, Jefferson, UPMC research programs

Treatment Programs in Harrisburg

Medical Detox

Safe, supervised withdrawal with 24/7 medical monitoring

Residential Treatment

Live-in programs with structured daily therapy and support

Outpatient Programs

PHP, IOP, and standard outpatient for flexible recovery

Sober Living

Supportive housing for continued recovery support

Insurance & Payment in Harrisburg

PA Medicaid covers comprehensive treatment. The state has expanded coverage and reduced barriers to access.

National Resources

Federal resources and hotlines available 24/7 for addiction support.

Free, confidential, 24/7, 365-day-a-year treatment referral and information service

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Research and information on drug use and addiction

Frequently Asked Questions

Important Notice

This website provides general information about addiction treatment facilities. It is not a substitute for professional medical advice, diagnosis, or treatment. If you are experiencing a mental health crisis, please call 988 (Suicide & Crisis Lifeline) or 911 for immediate assistance. For substance abuse help, call SAMHSA at 1-800-662-4357.

Data sourced from SAMHSA Treatment Locator, state licensing databases, and facility submissions.

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