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Drug & Alcohol Rehab Centers in Santa Ana, California

Find verified addiction treatment facilities in Santa Ana. Our directory includes 14 licensed rehabilitation centers offering detox, residential, outpatient, and specialty programs. Most facilities accept insurance.

Updated: December 18, 2025
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Showing 14 of 14 results

Cornerstone Adult Outpatient
+9 photos

Cornerstone Adult Outpatient

1950 East 17th Street, 92705
714-547-4300

Located in Santa Ana, CA, Cornerstone Adult Outpatient provides a range of services, including intensive outpatient treatment, outpatient programs, and outpatient day treatment specifically designed to address substance use challenges. This facility is equipped to serve a varied clientele, featuring specialized programs tailored for active duty military personnel, adult men, and adult women. Cornerstone employs a combination of evidence-based methods such as 12-step facilitation, brief intervention, and cognitive-behavioral therapy to deliver thorough care for adults and young adults of all genders. By focusing on personalized treatment plans in a nurturing atmosphere, the center commits to providing high-quality support for individuals seeking to recover from addiction. You can rely on Cornerstone Adult Outpatient for effective, customized treatment in a friendly environment.

Substance use treatment
Newport Academy
+9 photos

Newport Academy

9951 Highcliff Drive, 92705
877-820-6371

Situated in Santa Ana, CA, Newport Academy specializes in extensive substance use treatment and provides dedicated support for individuals facing significant mental health challenges alongside their addiction. The facility features a range of programs, including intensive outpatient care, long-term residential options, and outpatient services, catering to both adults and children/adolescents. Their therapeutic approach combines cognitive behavioral therapy, motivational interviewing, and strategies aimed at preventing relapse. Notably, Newport Academy offers customized programs specifically for adolescents, trauma survivors, and individuals dealing with both mental health issues and substance use disorders. Welcoming both male and female clients, Newport Academy is committed to delivering top-notch rehabilitation services that guide individuals on their path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos

Newport Institute

9881 Deerhaven Drive, 92705
855-272-7451

Newport Institute, situated in Santa Ana, CA, provides a wide array of rehabilitation services for both adults and young adults facing challenges with substance use disorders and co-occurring mental health conditions. The facility offers various treatment options, including intensive outpatient programs, long-term residential stays, and standard outpatient services. Their approach incorporates specialized methods like anger management, cognitive behavioral therapy, and relapse prevention. What sets Newport Institute apart is its commitment to trauma-informed care, along with LGBTQ-affirming programs and customized services for those with dual diagnoses. Catering to both male and female clients, the center emphasizes delivering high-quality, personalized care aimed at helping individuals achieve sustainable recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos

Newport Institute

12822 Periwinkle Drive, 92705
855-272-7451

Newport Institute, situated in Santa Ana, CA, provides extensive treatment for substance use as well as focused care for co-occurring mental health issues for both adults and children. The facility features a variety of programs, including intensive outpatient services, long-term residential care, and outpatient options, ensuring that treatment is customized to meet individual needs. Methods such as anger management, cognitive behavioral therapy, and relapse prevention are all part of the healing process. Additionally, specialized programs are available for LGBTQ individuals, trauma survivors, and those dealing with co-occurring disorders. Newport Institute is committed to offering exceptional, personalized care aimed at fostering lasting recovery and overall wellness for adults and young adults of all genders.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Newport Institute
+9 photos

Newport Institute

10022 Miramar Circle, 92705
855-272-7451

Newport Institute, situated in Santa Ana, CA, provides a well-rounded approach to substance use treatment while also addressing co-occurring mental health challenges in adults and severe emotional disturbances in children. The facility offers a variety of treatment options, including intensive outpatient, long-term residential, and outpatient programs. Clients benefit from evidence-based methods like cognitive behavioral therapy, motivational interviewing, and relapse prevention, all designed to meet the specific needs of those with trauma histories, co-occurring disorders, and members of the LGBTQ community. Newport Institute serves adults and young adults from all backgrounds, focusing on delivering high-quality care and creating personalized treatment plans that cater to each client's individual situation.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Pacific Sands Recovery Center
+9 photos

Pacific Sands Recovery Center

1909 West Carlton Place, 92704
844-568-7328

Situated in the heart of Santa Ana, CA, Pacific Sands Recovery Center provides a full range of services for detoxification, substance use issues, and co-occurring disorders among adults facing significant mental health challenges. The facility offers hospital inpatient detox and treatment, featuring specialized programs designed for adult men and women, as well as individuals who have encountered intimate partner violence and those affected by domestic violence. With an emphasis on 12-step facilitation, anger management, and brief interventions, Pacific Sands Recovery Center supports both adult and young adult clients by delivering customized care tailored to their needs. Discover exceptional care and individualized treatment at this esteemed rehabilitation center.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Phoenix House
+9 photos

Phoenix House

Orange County

1207 East Fruit Street, 92701
714-953-9373

Situated in Santa Ana, CA, Phoenix House provides a wide array of treatment solutions for those looking to recover from substance use and mental health disorders that often occur alongside it. The facility offers a mix of intensive outpatient, long-term residential, and outpatient programs, all grounded in evidence-based practices such as cognitive behavioral therapy and anger management. With a commitment to serving adult men and women, this center also supports clients who have faced intimate partner violence. By emphasizing personalized care, Phoenix House fosters a nurturing environment for both adults and young adults to experience healing and growth. If you’re in search of specialized treatment in a compassionate atmosphere, you can count on Phoenix House to be your partner in achieving lasting recovery.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Recovery Homes of America Inc
+9 photos

Recovery Homes of America Inc

1950 East 17th Street, 92705
714-567-5345

Situated in Santa Ana, CA, Recovery Homes of America Inc. provides exceptional substance use treatment for both adults and young adults. The center offers a variety of comprehensive programs, such as intensive outpatient treatment, outpatient services, and outpatient day treatment. With a strong emphasis on 12-step facilitation, brief intervention, and cognitive behavioral therapy, their approach is customized to address each individual's unique needs. Additionally, they have special programs designed specifically for active duty military personnel, as well as for adult men and women. Committed to offering care to all clients, this facility takes pride in providing high-quality, gender-specific treatment aimed at fostering lasting recovery.

Substance use treatment
Santa Ana Comprehensive Treatment Ctr
+9 photos

Santa Ana Comprehensive Treatment Ctr

California Treatment Services LLC

2101 East 1st Street, 92705
714-581-9181

Located in Santa Ana, CA, the Santa Ana Comprehensive Treatment Center provides a range of services including outpatient detoxification, substance use treatment, and therapies such as methadone, buprenorphine, or naltrexone. This facility specializes in 12-step facilitation, anger management, and brief intervention, making it a valuable resource for active-duty military personnel as well as adult men and women. Catering to adults and young adults of all genders, the center emphasizes personalized care tailored to each individual's unique needs. With a strong focus on delivering high-quality treatment, the Santa Ana Comprehensive Treatment Center stands out as a reliable option for those in search of effective addiction rehabilitation services in the local area.

DetoxificationSubstance use treatment
Orange County Healthcare Agency
+4 photos

Orange County Healthcare Agency

Drug Court and DUI Programs

401 West Civic Center Drive, 92701
714-480-6650

Situated in Santa Ana, CA, the Orange County Healthcare Agency provides a wide range of substance use treatment options. Their offerings include intensive outpatient programs, standard outpatient care, as well as outpatient treatments with methadone, buprenorphine, or naltrexone. This center is particularly adept at employing methods such as anger management, brief interventions, and cognitive behavioral therapy, all aimed at creating a personalized and effective treatment journey. Prioritizing individualized care, the facility serves both adults and young adults, regardless of gender. Committed to delivering high-quality support, the Orange County Healthcare Agency strives to assist clients in overcoming addiction and achieving sustained recovery.

Substance use treatment
PES/EBS Inc

PES/EBS Inc

600 West Santa Ana Boulevard, 92701
530-888-1010

PES/EBS Inc, situated in Santa Ana, CA, specializes in substance use treatment programs tailored for both adults and young adults. The facility offers a range of services, including intensive outpatient programs, general outpatient services, and options for outpatient treatment with methadone, buprenorphine, or naltrexone. Employing evidence-based methods, the center utilizes strategies like brief intervention, cognitive behavioral therapy, and the Matrix Model. With a commitment to high-quality care, PES/EBS Inc serves both male and female clients, including individuals who are navigating the criminal justice system. The center is devoted to providing customized support and effective treatments for those looking to overcome their addiction challenges.

Substance use treatment
Cooper Fellowship Inc - Placeholder

Cooper Fellowship Inc

409 North Cooper Street, 92703
714-554-1152

Cooper Fellowship Inc, located in Santa Ana, CA, provides long-term residential and round-the-clock care for adults and young adults dealing with substance use issues. This center places a strong emphasis on 12-step facilitation, anger management, and brief intervention strategies. They have distinct programs designed specifically for active duty military personnel, as well as for adult men and women. By focusing on gender-specific care, the facility is able to offer personalized treatment that meets the unique needs of both male and female clients. With its dedication to delivering high-quality care and specialized programs, Cooper Fellowship Inc is an essential resource for those seeking effective and compassionate addiction treatment in a residential environment.

Substance use treatment
Straight Talk Clinics Inc - Placeholder

Straight Talk Clinics Inc

Gerry House

1225 West 6th Street, 92703
714-972-1402

Located in Santa Ana, CA, Straight Talk Clinics Inc provides specialized treatment programs for substance use in a welcoming residential atmosphere. This facility offers a variety of options, including long-term, short-term, and 24-hour residential treatment specifically designed for adult men who are dealing with addiction issues. Their comprehensive approach incorporates elements like 12-step facilitation, anger management, and brief intervention strategies. Moreover, the program prioritizes issues such as intimate partner violence, domestic violence, and sexual abuse, ensuring that clients receive care tailored to their unique needs in a safe and nurturing environment. Catering to a diverse clientele that includes adults, seniors, and young adults, Straight Talk Clinics Inc is dedicated to providing high-quality support and care to foster lasting recovery.

Substance use treatment
Villa Center Inc - Placeholder

Villa Center Inc

The Villa

910 North French Street, 92701
714-541-2732

Situated in Santa Ana, CA, Villa Center Inc specializes in delivering high-quality substance use treatment specifically for adult women, all within a caring and secure environment. The facility offers a range of programs, including long-term, short-term, and 24-hour residential options, all designed to cater to clients who have faced intimate partner or domestic violence. Villa Center Inc employs tailored approaches such as 12-step facilitation, anger management, and brief interventions to ensure comprehensive care for a diverse clientele, ranging from young adults to seniors. What sets this center apart is its dedicated programs for active duty military personnel, making it an excellent choice for those in search of gender-specific and trauma-informed treatment.

Substance use treatment

Addiction Treatment in Santa Ana, California

Santa Ana offers specialized addiction treatment options, from medical detox to long-term residential care. Whether you're seeking help for yourself or a loved one,Santa Ana's treatment centers provide professional, compassionate care with various program types and payment options.

Why Choose Treatment in Santa Ana?
  • Specialized treatment centers with various programs
  • Licensed facilities with experienced professionals
  • Local recovery community and support groups
  • Full continuum of care from detox to aftercare
  • Largest selection of treatment facilities in the nation
  • Leading-edge treatment technologies and approaches

Treatment Programs in Santa Ana

Medical Detox

Safe, supervised withdrawal with 24/7 medical monitoring

Residential Treatment

Live-in programs with structured daily therapy and support

Outpatient Programs

PHP, IOP, and standard outpatient for flexible recovery

Sober Living

Supportive housing for continued recovery support

Insurance & Payment in Santa Ana

Medi-Cal offers comprehensive substance abuse coverage. California has strong mental health parity laws ensuring insurance coverage for treatment.

National Resources

Federal resources and hotlines available 24/7 for addiction support.

Free, confidential, 24/7, 365-day-a-year treatment referral and information service

Find treatment facilities in your area

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Research and information on drug use and addiction

Frequently Asked Questions

Important Notice

This website provides general information about addiction treatment facilities. It is not a substitute for professional medical advice, diagnosis, or treatment. If you are experiencing a mental health crisis, please call 988 (Suicide & Crisis Lifeline) or 911 for immediate assistance. For substance abuse help, call SAMHSA at 1-800-662-4357.

Data sourced from SAMHSA Treatment Locator, state licensing databases, and facility submissions.

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