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South Dakota12 facilities

Drug & Alcohol Rehab Centers in Sioux Falls, South Dakota

Find verified addiction treatment facilities in Sioux Falls. Our directory includes 12 licensed rehabilitation centers offering detox, residential, outpatient, and specialty programs. Most facilities accept insurance.

Updated: December 19, 2025
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Avera McKennan Hospital (BHS)
+9 photos

Avera McKennan Hospital (BHS)

Addiction Recovery Program

Avera Professional Plaza, 57105
605-322-4079

Avera McKennan Hospital (BHS) located in Sioux Falls, SD, provides specialized treatment for both substance use and co-occurring disorders in both adults and children. The center offers a range of programs, including intensive outpatient, outpatient, and regular outpatient options. Utilizing techniques such as cognitive behavioral therapy, motivational interviewing, and relapse prevention, Avera McKennan Hospital ensures that each individual receives tailored care. This facility is dedicated to serving adults and seniors of all genders, distinguishing itself through a holistic approach to tackling substance use and mental health challenges. They are committed to delivering quality care and support to those on their journey toward recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sioux Falls VAHCS
+9 photos

Sioux Falls VAHCS

- - -, 57105
605-336-3230

Sioux Falls VAHCS, located in Sioux Falls, SD, provides a wide array of addiction treatment services aimed at both adults and young adults. The center specializes in intensive outpatient programs, outpatient detoxification, and personalized outpatient services designed for those dealing with both mental health and substance use issues. Emphasizing techniques such as 12-step facilitation, anger management, and brief interventions, this facility supports clients who have faced challenges such as intimate partner violence, trauma, and domestic abuse. Welcoming both male and female clients, the Sioux Falls VAHCS is dedicated to offering top-notch care to help individuals on their path to recovery.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Tallgrass Recovery and
+9 photos

Tallgrass Recovery and

Sober Living Homes

27048 Tallgrass Avenue, 57108
605-368-5559

Tallgrass Recovery, situated in Sioux Falls, SD, provides a wide-ranging approach to substance use treatment within a residential setting. Emphasizing 12-step facilitation and personalized programs, this facility serves both adults and young adults on their journey to recovery. With specialized care available for male and female clients, the center ensures that every individual receives a customized approach. Their short-term and round-the-clock residential programs create a nurturing atmosphere ideal for those striving to conquer addiction. Tallgrass Recovery’s dedication to high-quality care and individualized treatment truly positions it as a leading option for anyone in need of effective rehabilitation services.

Substance use treatment
Sioux Falls Treatment Center LLC
+7 photos

Sioux Falls Treatment Center LLC

2519 West 8th Street, 57104
605-332-3236

Sioux Falls Treatment Center LLC, located in Sioux Falls, SD, provides outpatient detoxification, substance use treatment, as well as methadone, buprenorphine, or naltrexone therapy for adults and young adults. Employing evidence-based methods, their offerings include brief interventions, cognitive-behavioral therapy, and motivational incentives through contingency management. What sets this facility apart is its tailored approach, serving both male and female clients. Committed to delivering quality care, Sioux Falls Treatment Center LLC fosters a supportive environment for individuals seeking effective and personalized addiction treatment services.

DetoxificationSubstance use treatment
Arch
+2 photos

Arch

516 West 12th Street, 57104
605-336-2556

Situated in Sioux Falls, SD, "Arch" provides a wide array of substance use treatment options along with specialized support for adults facing serious mental health challenges and for children dealing with emotional disturbances. The facility offers various treatment formats, including intensive outpatient programs, long-term residential stays, and outpatient services, all designed to meet individual needs. Utilizing proven methods like 12-step facilitation, brief interventions, and cognitive behavioral therapy, "Arch" ensures that care is both effective and personalized. They serve adult men and women, as well as clients with co-occurring disorders, with specialized programs tailored to different genders and age groups. Committed to delivering high-quality care and customized treatment plans, this center is focused on guiding clients through their recovery journey.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Volunteers of America Dakotas
+2 photos

Volunteers of America Dakotas

1310 West 51st Street, 57105
605-334-1414

Situated in Sioux Falls, SD, Volunteers of America Dakotas delivers a wide range of substance use treatment options for both adults and seniors. This facility offers intensive outpatient treatment, long-term residential care, and various outpatient services. With tailored programs for adolescents, adult women, and individuals who have faced trauma, the center effectively addresses diverse needs. By employing methods like 12-step facilitation, anger management, and brief interventions, the team is committed to providing personalized care. Open to both men and women, Volunteers of America Dakotas strives to provide top-notch rehabilitation services within a supportive and compassionate setting.

Substance use treatment
Keystone Treatment Center
+1 photos

Keystone Treatment Center

Outpatient Program

3800 South Kiwanis Avenue, 57105
888-450-7844

Keystone Treatment Center, situated in Sioux Falls, SD, offers a wide range of substance use treatment programs. Catering to both adults and adolescents, the facility features intensive outpatient, outpatient, and regular outpatient treatment options. The center employs evidence-based strategies, including 12-step facilitation, cognitive behavioral therapy, and contingency management, customizing the treatment process to meet each person's unique needs. Notably, Keystone Treatment Center has expertise in assisting clients facing both mental health and substance use disorders simultaneously. With programs available for both men and women, the center is dedicated to providing exceptional care for everyone seeking to recover from addiction.

Substance use treatment
Carroll Institute - Placeholder

Carroll Institute

Outpatient Alcohol and Drug Center

310 South 1st Avenue, 57104
605-336-2556

Carroll Institute, located in Sioux Falls, SD, provides tailored treatment programs for substance use disorders and co-occurring conditions, catering to both adults and children. Their range of services includes intensive outpatient and standard outpatient treatment options. Utilizing methods such as 12-step facilitation, anger management, and brief intervention, the facility ensures a supportive environment. Recognizing the unique needs of different demographics, Carroll Institute offers specialized programs for adolescents as well as adult men and women. Their comprehensive treatment plans are designed to assist individuals of all genders, making Carroll Institute a reputable choice for effective rehabilitation services in the Sioux Falls area.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Counseling Resources - Placeholder

Counseling Resources

4109 South Carnegie Circle, 57106
605-331-2419

Situated in Sioux Falls, SD, Counseling Resources provides a wide array of treatment options for substance use and co-occurring disorders, serving both adults and children/adolescents. The facility features intensive outpatient, outpatient, and regular outpatient programs that incorporate methods like anger management, brief interventions, and cognitive behavioral therapy. With a strong emphasis on personalized care, the center accommodates both male and female clients alike. Counseling Resources truly distinguishes itself through its dedication to high-quality care and customized treatment plans, making it an excellent option for individuals looking for effective and personalized rehabilitation services in the region.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Dakota Drug and Alcohol Prevention Inc - Placeholder

Dakota Drug and Alcohol Prevention Inc

Prairie View Prevention Services

822 East 41st Street, 57105
605-331-5724

Dakota Drug and Alcohol Prevention Inc, based in Sioux Falls, SD, provides specialized outpatient treatment for substance use geared towards adults, adolescents, and young adults. The facility emphasizes techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing, delivering personalized care for all clients, regardless of gender. They also offer distinct programs designed for adolescents, young adults, and individuals within the criminal justice system. With a commitment to a comprehensive approach, the center ensures high-quality support for those on the path to recovery. If you're looking for effective addiction treatment in a nurturing atmosphere, you might want to explore the services available at Dakota Drug and Alcohol Prevention Inc.

Substance use treatment
Glory House of Sioux Falls - Placeholder

Glory House of Sioux Falls

4000 South West Avenue, 57105
605-332-3273

Situated in Sioux Falls, SD, Glory House of Sioux Falls provides long-term residential treatment specifically designed for adult men struggling with substance use disorders. This facility is well-equipped to offer specialized care to clients who also face co-occurring mental health issues. By employing evidence-based methods like Cognitive Behavioral Therapy and the Matrix Model, they ensure those in their care receive effective support. The program is particularly attentive to adults, seniors, and young adults who have endured trauma, creating a safe and nurturing atmosphere conducive to healing. Additionally, Glory House of Sioux Falls offers transitional housing and sober living options, demonstrating their commitment to delivering high-quality care for individuals on their journey to recovery from addiction and mental health challenges.

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Sands Freedom Center - Placeholder

Sands Freedom Center

3930 South West Avenue, 57105
605-988-9133

Nestled in Sioux Falls, SD, Sands Freedom Center provides a variety of evidence-based treatment options for both substance use disorders and co-occurring mental health challenges in adults and children. The center’s offerings include intensive outpatient programs, long-term residential care, and outpatient services. These programs feature approaches like cognitive behavioral therapy, contingency management, and the Matrix Model. Sands Freedom Center serves adult men and women, young adults, and individuals who have undergone trauma, ensuring that care is customized to meet each person's unique needs. With an emphasis on high-quality, personalized treatment, this facility creates a nurturing environment for those on the journey to recovery and healing.

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Addiction Treatment in Sioux Falls, South Dakota

Sioux Falls offers specialized addiction treatment options, from medical detox to long-term residential care. Whether you're seeking help for yourself or a loved one,Sioux Falls's treatment centers provide professional, compassionate care with various program types and payment options.

Why Choose Treatment in Sioux Falls?
  • Specialized treatment centers with various programs
  • Licensed facilities with experienced professionals
  • Local recovery community and support groups
  • Full continuum of care from detox to aftercare
  • Strong Native American treatment programs
  • Lower overdose rates than national average

Treatment Programs in Sioux Falls

Medical Detox

Safe, supervised withdrawal with 24/7 medical monitoring

Residential Treatment

Live-in programs with structured daily therapy and support

Outpatient Programs

PHP, IOP, and standard outpatient for flexible recovery

Sober Living

Supportive housing for continued recovery support

Insurance & Payment in Sioux Falls

SD Medicaid covers behavioral health services. Many facilities assist with payment arrangements.

National Resources

Federal resources and hotlines available 24/7 for addiction support.

Free, confidential, 24/7, 365-day-a-year treatment referral and information service

Find treatment facilities in your area

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Research and information on drug use and addiction

Frequently Asked Questions

Important Notice

This website provides general information about addiction treatment facilities. It is not a substitute for professional medical advice, diagnosis, or treatment. If you are experiencing a mental health crisis, please call 988 (Suicide & Crisis Lifeline) or 911 for immediate assistance. For substance abuse help, call SAMHSA at 1-800-662-4357.

Data sourced from SAMHSA Treatment Locator, state licensing databases, and facility submissions.

Explore more treatment options throughout South Dakota