Penn Spine and Rehab Logo

Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(223) 235-7839
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 8160 prescription drug abuse rehab centers

Memphis Recovery Centers Inc
+9 photos

Memphis Recovery Centers Inc

Memphis, TN

Located in Memphis, TN, Memphis Recovery Centers Inc offers a wide range of treatment options for substance use issues and co-occurring mental health disorders, catering to both adults and children. The center features various programs, including intensive outpatient, long-term residential, and regular outpatient services. Their approach is grounded in evidence-based practices, incorporating methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. A key focus of the facility is providing trauma-informed care, particularly for adolescents, individuals facing co-occurring disorders, and those who have experienced trauma. With an emphasis on personalized treatment, Memphis Recovery Centers Inc welcomes both male and female clients, delivering tailored care to support each person's journey to recovery.

Golden Peak Recovery
+9 photos

Golden Peak Recovery

Denver, CO

Golden Peak Recovery, located in Denver, CO, offers a wide array of treatment programs designed for individuals facing substance use disorders and related mental health issues. The center features long-term residential options, detoxification services, and round-the-clock care for both adults and young adults. With customized strategies that include 12-step facilitation, anger management, and brief interventions, Golden Peak caters to a variety of client needs. Additionally, the facility provides specialized programs for individuals who have experienced trauma, those with co-occurring disorders, and those grappling with pain alongside substance use. Golden Peak Recovery is committed to delivering high-quality care in a nurturing environment, supporting both male and female clients on their paths to recovery.

MPower Wellness of Pennsylvania LLC
+9 photos

MPower Wellness of Pennsylvania LLC

Exton, PA

MPower Wellness of Pennsylvania LLC, located in Exton, PA, provides a thorough approach to treating substance use issues alongside specialized care for those facing both substance use and serious mental health challenges. The center features a range of services, including intensive outpatient programs, outpatient day treatment, and partial hospitalization, specifically designed for both adults and young adults. With a strong emphasis on 12-step facilitation, anger management, and brief intervention techniques, this facility is well-equipped to assist clients who have experienced trauma as well as those dealing with co-occurring mental health and substance use disorders. MPower Wellness of Pennsylvania LLC proudly serves both men and women, delivering high-quality care aimed at helping individuals on their path to recovery.

Healing Place
+9 photos

Healing Place

Louisville, KY

Situated in Louisville, KY, Healing Place specializes in rehabilitation services tailored specifically for adult men facing substance use disorders. The facility offers a wide range of comprehensive treatment options, including detoxification, intensive outpatient services, and long-term residential programs. By implementing evidence-based methods such as Cognitive Behavioral Therapy and 12-step facilitation, the center emphasizes a personalized approach to care. What sets Healing Place apart is its transitional housing and sober living programs, which play a crucial role in supporting clients as they navigate their recovery journey. With a commitment to providing quality care for adults and seniors, Healing Place also focuses on those dealing with co-occurring pain and substance use disorders, ensuring that each individual receives the attention and treatment they need.

Valley Recovery Center of Agua Dulce
+9 photos

Valley Recovery Center of Agua Dulce

Santa Clarita, CA

Nestled in Santa Clarita, CA, the Valley Recovery Center of Agua Dulce specializes in offering a wide range of addiction treatment services specifically designed for adult men. The facility features residential detoxification, round-the-clock residential care, and short-term residential programs. With a strong emphasis on 12-step facilitation, anger management, and brief interventions, this center effectively supports individuals coping with both substance use issues and serious mental health challenges. They also provide unique programs tailored for active duty military members, adult men, and survivors of intimate partner violence. Catering to a diverse clientele that includes adults, seniors, and young adults, Valley Recovery Center of Agua Dulce is committed to delivering high-quality care within a nurturing environment specifically suited for male clients.

Community Medical Services
+9 photos

Community Medical Services

Buckeye, AZ

Nestled in Buckeye, AZ, Community Medical Services is dedicated to offering outpatient treatment for substance use, with a particular focus on methadone or buprenorphine, as well as naltrexone therapies. The center employs evidence-based practices, including cognitive behavioral therapy, contingency management with motivational incentives, and motivational interviewing, to ensure effective care. What truly sets this facility apart is its specialized focus on pregnant and postpartum women, while also welcoming adults and young adults of all gender identities. At Community Medical Services, quality care is a priority. They create personalized treatment plans tailored to the unique needs of each individual who seeks help in their recovery journey. If you’re searching for a supportive and specialized environment for addiction treatment, this facility is committed to guiding you toward sobriety.

Parkman Recovery Center
+9 photos

Parkman Recovery Center

Warren, OH

Parkman Recovery Center, located in Warren, OH, specializes in providing a full range of addiction treatment services specifically designed for adult men. The facility features hospital inpatient detoxification, effective substance use treatment, and transitional housing all within a nurturing atmosphere. Focusing on methodologies such as 12-step facilitation, anger management, and cognitive behavioral therapy, the center welcomes adults, seniors, and young adults who are in search of high-quality care. One of the key aspects that distinguishes the program is its attention to the unique needs of men, which fosters personalized support and enhances treatment effectiveness. At Parkman Recovery Center, the mission is clear: to guide individuals toward lasting sobriety and help them successfully reintegrate into society.

Lotus Recovery Centers
+9 photos

Lotus Recovery Centers

Comfort, WV

Nestled in Comfort, WV, Lotus Recovery Centers provides a wide array of services designed for addiction treatment. The facility is particularly focused on detoxification and addressing substance use challenges, offering various options like long-term residential care, residential detox programs, and round-the-clock residential services. They employ methods like 12-step facilitation, anger management, and brief interventions, making it accessible to both adult men and women, including those who are on active military duty. Lotus Recovery Centers is committed to delivering individualized treatment plans for both adults and young adults, ensuring that every client receives the specific care they need. Whether someone is looking for help for themselves or for a family member, they can count on the center to provide top-notch, gender-sensitive care at this well-regarded rehabilitation facility.

Alvarado Parkway Institute
+9 photos

Alvarado Parkway Institute

La Mesa, CA

Alvarado Parkway Institute, located in La Mesa, CA, offers a wide range of rehabilitation services. These encompass detoxification, treatment for substance use disorders, and specialized support for adults facing both serious mental health issues and those with serious emotional disturbances in children. The facility features hospital inpatient detoxification, effective treatment options, and round-the-clock care. Among the various therapies provided, you’ll find 12-step facilitation, anger management, and brief interventions. Additionally, the institute has specialized programs designed for clients who have endured sexual abuse or trauma, as well as those with co-occurring mental health and substance use issues. Alvarado Parkway Institute is dedicated to delivering quality care that meets the unique needs of adults and young adults of all genders.

Willows at Red Oak Recovery
+9 photos

Willows at Red Oak Recovery

Fletcher, NC

Located in Fletcher, NC, Willows at Red Oak Recovery is dedicated to offering specialized rehabilitation services aimed at adult women dealing with substance use issues and serious co-occurring mental health disorders. The center features a range of programs, including intensive outpatient, long-term residential, and outpatient options, all designed to meet the distinct needs of women who have faced intimate partner violence. With a strong emphasis on 12-step facilitation, anger management, and cognitive behavioral therapy, Willows at Red Oak Recovery provides comprehensive care in a safe and nurturing environment. The facility caters to a diverse clientele, including seniors, young adults, and adults, and is recognized for its high-quality treatment programs and tailored services specifically for female clients.

Ohlhoff Recovery Programs
+9 photos

Ohlhoff Recovery Programs

San Francisco, CA

Ohlhoff Recovery Programs, situated in San Francisco, CA, specializes in long-term residential treatment for adult and senior men dealing with substance use issues. This facility offers a range of options, including transitional housing, halfway houses, and sober living environments, all designed to provide continuous care and support around the clock. The center employs evidence-based methods such as 12-step facilitation, brief interventions, and cognitive behavioral therapy to effectively tackle addiction challenges. With a strong emphasis on personalized care, Ohlhoff Recovery Programs customizes its treatment plans to suit the specific needs of each resident. If you or someone you know is looking for effective and compassionate addiction treatment in a nurturing environment, this facility is committed to helping individuals embark on the path to lasting recovery.

Damon House Inc
+9 photos

Damon House Inc

New Brunswick, NJ

Nestled in New Brunswick, NJ, Damon House Inc provides a thorough substance use treatment program. The facility specializes in intensive outpatient care, alongside outpatient and regular outpatient options, creating a diverse array of services. These include anger management, brief intervention sessions, and cognitive behavioral therapy. They also offer specialized programs designed for active duty military members, adult men, and adult women. Catering to both adults and young adults of all genders, Damon House Inc is committed to delivering quality care through evidence-based methods. This facility stands out as a vital resource for anyone looking for effective and personalized treatment for addiction in a nurturing atmosphere.

Hunterdon Medical Center/Add Trt Servs
+9 photos

Hunterdon Medical Center/Add Trt Servs

Flemington, NJ

Hunterdon Medical Center/Add Trt Servs, located in Flemington, NJ, provides extensive substance use treatment tailored for adults facing co-occurring serious mental health issues. The center offers a range of services, including intensive outpatient, outpatient, and partial hospitalization programs. Their treatment methods incorporate effective strategies such as 12-step facilitation and anger management. The facility specializes in serving clients with dual diagnoses, and it caters to both male and female patients, including seniors. With a strong emphasis on evidence-based care and personalized treatment plans, Hunterdon Medical Center/Add Trt Servs is committed to delivering high-quality rehabilitation for adults and seniors navigating the challenges of substance use disorders alongside mental health difficulties.

Sacramento Comprehensive Treatment Ctr
+9 photos

Sacramento Comprehensive Treatment Ctr

Sacramento, CA

Sacramento Comprehensive Treatment Center, located in Sacramento, CA, provides outpatient detoxification and treatment for substance use tailored for adults and young adults. The facility utilizes a variety of therapeutic approaches including cognitive behavioral therapy, motivational interviewing, and contingency management, ensuring that care is personalized for each individual. With dedicated programs designed to address the unique needs of both male and female clients, this center is focused on helping individuals on their journey to recovery from addiction. Their emphasis on quality care and evidence-based practices creates an inviting atmosphere for those ready to begin their path to sobriety.

Greater Seacoast Community Health
+9 photos

Greater Seacoast Community Health

Portsmouth, NH

Situated in Portsmouth, NH, Greater Seacoast Community Health specializes in outpatient services aimed at detoxification and substance use treatment. The facility offers a range of options, including outpatient detoxification, as well as treatment with methadone, buprenorphine, or naltrexone. Additionally, they employ methods like brief intervention, cognitive behavioral therapy, and motivational interviewing. With a strong emphasis on personalized care, this center serves adults and young adults of all genders. Greater Seacoast Community Health is recognized for its customized programs and dedication to delivering high-quality support for those seeking help with addiction.

Chapa de Indian Health Program Inc
+9 photos

Chapa de Indian Health Program Inc

Auburn, CA

Chapa de Indian Health Program Inc, located in Auburn, CA, provides a wide array of outpatient services designed for individuals who are looking for detoxification, substance use treatment, and support for mental health issues that occur alongside substance use. This facility is particularly attentive to the specific needs of pregnant and postpartum women, while also offering dedicated programs for adults and seniors. It ensures that both men and women receive gender-specific care. The center employs various therapeutic techniques including anger management, brief intervention, and cognitive behavioral therapy, allowing for personalized treatment plans for each client. With options for outpatient detoxification as well as methadone and buprenorphine treatments, Chapa de Indian Health Program enhances accessibility and effectiveness, ensuring that individuals receive the high-quality care they deserve.

Salvation Army Harbor Light Center
+9 photos

Salvation Army Harbor Light Center

Indianapolis, IN

Situated in Indianapolis, IN, the Salvation Army Harbor Light Center offers a wide array of addiction treatment services tailored to meet diverse needs. The facility encompasses detoxification, substance use treatment, transitional housing, halfway house options, and sober living arrangements. Various treatment formats are available, such as intensive outpatient programs, long-term residential stays, and standard outpatient services. Using methods like 12-step facilitation, anger management techniques, and cognitive behavioral therapy, the center serves both adult men and women, including individuals who have dealt with intimate partner violence. With dedicated programs designed for young adults and an emphasis on gender-specific care, the Salvation Army Harbor Light Center strives to provide top-notch, individualized support for those on their journey to recovery from addiction.

Serenity Recovery Centers Inc
+9 photos

Serenity Recovery Centers Inc

Memphis, TN

Serenity Recovery Centers Inc, situated in Memphis, TN, provides a wide array of services for those struggling with substance use. The facility specializes in intensive outpatient treatment, long-term residential programs, and various outpatient options. Aiming to support adult men and women, the center emphasizes 12-step facilitation, anger management, and brief interventions, catering particularly to clients who have faced intimate partner or domestic violence. Whether serving adults or young adults, Serenity Recovery Centers Inc is dedicated to offering personalized care that meets the unique needs of each individual. Additionally, the center features transitional housing and specialized programs targeting different populations, making it a place that truly values quality care and holistic healing for anyone on their recovery journey.

DUI Community Counseling Inc
+9 photos

DUI Community Counseling Inc

Chicago, IL

Located in Chicago, IL, DUI Community Counseling Inc offers a range of specialized treatment options for substance use disorders. These include intensive outpatient treatment, outpatient programs, and regular outpatient services. The center employs evidence-based methods such as anger management, brief interventions, and cognitive behavioral therapy. Interestingly, they also have a dedicated program for clients involved in the criminal justice system. Serving adults, children, adolescents, and individuals of all genders, this facility is committed to providing personalized care that meets the needs of a diverse clientele. With a strong emphasis on quality and individualized treatment, DUI Community Counseling Inc stands out as a dependable option for those seeking effective addiction rehabilitation in the Chicago area.

Meridian Behavioral Healthcare Inc
+9 photos

Meridian Behavioral Healthcare Inc

Gainesville, FL

Meridian Behavioral Healthcare Inc, situated in Gainesville, FL, offers a wide array of rehabilitation services tailored for those in need. The center specializes in intensive outpatient treatment, long-term residential programs, and outpatient services aimed at helping adults and young adults who are facing substance use disorders along with co-occurring mental health issues. Recognizing the unique challenges faced by specific populations, Meridian has developed targeted programs for active duty military personnel, as well as for adult men and women. The facility employs evidence-based strategies like 12-step facilitation, anger management, and cognitive behavioral therapy to provide effective, high-quality care. With a focus on creating personalized treatment plans, Meridian ensures that both male and female clients receive the support they need for successful, lasting recovery.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • •Tolerance development requiring escalating doses for the same effect
  • •Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • •Genetic predisposition to addiction
  • •Mental health conditions that drive medication misuse
  • •Doctor shopping and obtaining multiple prescriptions
  • •Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab