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Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

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Showing 20 of 8160 prescription drug abuse rehab centers

Topsail Addiction Treatment Inc
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Topsail Addiction Treatment Inc

North Andover, MA

Topsail Addiction Treatment Inc, situated in North Andover, MA, delivers extensive substance use treatment for both adults and young adults. This center offers various options, including intensive outpatient treatment, general outpatient services, and daytime outpatient care or partial hospitalization. Emphasizing 12-step facilitation, anger management, and brief intervention techniques, Topsail Addiction Treatment serves active duty military members as well as adult men and women. The facility is inclusive and provides high-quality care that aligns with the individual needs of each client. If you're looking for specialized addiction treatment within a nurturing environment, Topsail Addiction Treatment is ready to support you.

Rose House
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Rose House

Lafayette, CO

Situated in Lafayette, CO, Rose House specializes in rehabilitation services specifically designed for adult women. The facility features a diverse range of treatment options, which encompass detoxification, substance use treatment, transitional housing, and sober living environments. Rose House is committed to offering tailored support, focusing on intensive outpatient treatment, long-term residential care, and outpatient services. This organization caters to the unique needs of clients who have faced intimate partner violence, domestic violence, or sexual abuse. By employing methods like 12-step facilitation, anger management, and brief intervention, Rose House aims to create a comprehensive and personalized recovery experience. With a focus on adults, seniors, and young adults, the facility is dedicated to delivering high-quality care for women in search of addiction treatment.

Allentown Comprehensive Treatment Ctr
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Allentown Comprehensive Treatment Ctr

Orefield, PA

Situated in Orefield, PA, the Allentown Comprehensive Treatment Center stands out as a leading option for outpatient substance use treatment. This facility offers a variety of services, including outpatient therapy using methadone, buprenorphine, or naltrexone, as well as regular outpatient treatment. They also feature specialized programs tailored for active duty military personnel, adult men, and adult women. With an emphasis on anger management, cognitive behavioral therapy, and motivational interviewing, the center serves both adults and young adults, regardless of gender. The Allentown Comprehensive Treatment Center is committed to providing top-notch care for those seeking effective and well-rounded addiction treatment services.

Covenant House Florida
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Covenant House Florida

Fort Lauderdale, FL

Covenant House Florida, located in Fort Lauderdale, FL, provides an extensive range of substance use treatment options, including long-term residential, 24-hour residential, and short-term residential programs. The center focuses on several therapeutic methods, such as 12-step facilitation, anger management, and brief intervention strategies. They also offer distinctive programs designed for clients who have faced trauma, as well as those dealing with co-occurring mental health and substance use disorders, including young adults. This facility caters to both adults and young adults, ensuring specialized care for male and female clients alike. At Covenant House Florida, the commitment to delivering personalized, high-quality care underlines their mission to support individuals on their recovery journey.

Compassionate Recovery Care
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Compassionate Recovery Care

Hermitage, TN

Located in Hermitage, TN, Compassionate Recovery Care provides outpatient detoxification and substance use treatment while also focusing on individuals dealing with co-occurring substance use and significant mental health issues for adults, as well as serious emotional disturbances in children. This facility emphasizes personalized care and employs various methods, including anger management, brief interventions, and cognitive behavioral therapy. With a commitment to customization, the program serves adults and young adults of every gender. Among its outpatient offerings, the center includes detoxification services and treatments with methadone/buprenorphine or naltrexone. Compassionate Recovery Care is dedicated to delivering high-quality, individualized care that meets the distinct needs of each client.

Recovery Is Happening
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Recovery Is Happening

Rochester, MN

"Recovery Is Happening," situated in Rochester, MN, specializes in providing thorough substance use treatment designed for adults, seniors, and young adults alike. The center offers a variety of services, including intensive outpatient treatment, long-term residential care, and outpatient services that are customized to meet each person's unique needs. With methods such as 12-step facilitation, cognitive behavioral therapy, and contingency management/motivational incentives, the facility adopts a holistic approach to recovery. Committed to personalized care, the center welcomes both male and female clients, fostering an inclusive and supportive atmosphere. If you or someone you care about is in need of effective addiction treatment options, "Recovery Is Happening" is here to help individuals navigate their journey toward lasting recovery.

Hogar Crea Tortugo
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Hogar Crea Tortugo

San Juan, PR

Hogar Crea Tortugo, situated in San Juan, PR, is a long-term residential rehabilitation center dedicated to helping adult men dealing with substance use challenges. The facility provides around-the-clock care and emphasizes effective treatment methods like 12-step facilitation, brief interventions, and cognitive behavioral therapy. At Hogar Crea Tortugo, there are specialized programs available for active duty military personnel, adult men, and those who have faced issues related to intimate partner or domestic violence. The center is committed to delivering tailored services for adults, seniors, and young adults, ensuring that quality care and evidence-based practices remain at the forefront of their support as individuals work towards recovery.

Clear Behavioral Health
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Clear Behavioral Health

Torrance, CA

Located in Torrance, CA, Clear Behavioral Health provides a variety of evidence-based rehabilitation services for those struggling with substance use disorders and co-occurring mental health challenges. They offer several types of programs, including intensive outpatient treatment, outpatient day treatment, and partial hospitalization, all designed to address the unique needs of adult men and women. The center excels in areas such as 12-step facilitation, anger management, and brief intervention techniques. Additionally, they have distinctive programs that cater specifically to clients who have faced trauma. With a strong emphasis on delivering quality care and personalized treatment, Clear Behavioral Health creates a nurturing environment for both adults and young adults on their journey to recovery.

Tree House Recovery PDX
+9 photos

Tree House Recovery PDX

Portland, OR

Tree House Recovery PDX, located in Portland, OR, provides a range of treatment options including intensive outpatient care, outpatient services, and day treatment specifically designed for male adults, seniors, and young adults facing substance use challenges. The facility emphasizes a variety of therapeutic approaches such as 12-step facilitation, anger management, and cognitive behavioral therapy. They also offer specialized programs for active duty military personnel, adult men, and those who have experienced trauma. With a comprehensive approach, Tree House Recovery PDX tailors its services to the unique needs of each individual, ensuring they receive quality treatment and support. If you or someone you know is in search of effective and personalized care for substance use issues, Tree House Recovery PDX may be the ideal starting point for your recovery journey.

Lions Gate Recovery
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Lions Gate Recovery

Cedar City, UT

Situated in Cedar City, UT, Lions Gate Recovery delivers thorough substance use treatment for both adults and young adults. The center features a range of options, including intensive outpatient treatment, outpatient services, and day programs. Additionally, there are specialized tracks designed specifically for active duty military members, as well as separate programs for adult men and women. Lions Gate Recovery employs evidence-based practices such as 12-step facilitation, anger management, and brief interventions to effectively tackle addiction. With an emphasis on high-quality care, this facility provides customized rehabilitation programs, ensuring that both male and female clients receive the tailored support they require.

Tacoma Pierce County Health Department
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Tacoma Pierce County Health Department

Tacoma, WA

Situated in Tacoma, WA, the Tacoma Pierce County Health Department provides a wide array of substance use treatment options for both adults and young adults. Their outpatient services include treatments like methadone, buprenorphine, or naltrexone, along with regular outpatient care, brief interventions, cognitive behavioral therapy, and motivational interviewing. The center emphasizes personalized care, featuring specialized programs specifically for adult women and those who are pregnant or in the postpartum period. Clients can anticipate high-quality support that caters to their unique needs, accompanied by a variety of services aimed at assisting both male and female clients in their recovery journey.

Saint Annes Home
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Saint Annes Home

Chicago, IL

Saint Annes Home, situated in Chicago, IL, provides long-term residential care for adult women who are looking for substance use treatment in a nurturing and secure setting. The facility is dedicated to transitional housing and halfway house services, specifically designed for clients recovering from intimate partner violence, domestic violence, and sexual abuse. By employing evidence-based methods such as 12-step facilitation and contingency management, the center delivers thorough care for both young adults and adults. With an emphasis on empowering women on their journey to recovery, Saint Annes Home prioritizes quality treatment through tailored programs and heartfelt support.

Ona Treatment Center
+9 photos

Ona Treatment Center

Browns Valley, CA

Located in Browns Valley, CA, Ona Treatment Center provides thorough substance use treatment tailored for both adults and young adults facing co-occurring mental health challenges. The center features a range of options, including long-term and short-term residential programs. Their approach incorporates specialized care, utilizing methods such as 12-step facilitation, anger management, and brief intervention strategies. Additionally, they offer unique programs designed specifically for clients who have experienced trauma and those with co-occurring disorders. Catering to both men and women, this facility is dedicated to providing quality care and support, creating a safe and structured environment for individuals on their path to recovery.

Freedom Recovery
+9 photos

Freedom Recovery

Columbus, OH

Freedom Recovery, located in Columbus, OH, specializes in providing substance use treatment for both adults and young adults. This center offers a range of programs, including intensive outpatient, outpatient, and standard outpatient treatments that are customized to meet each person's unique needs. They employ various strategies, such as 12-step facilitation, Contingency Management, and the Matrix Model, to create a thorough and personalized path to recovery. With a strong emphasis on individualized care, Freedom Recovery serves both male and female clients who are looking for effective support and treatment. Experience top-notch care in a welcoming atmosphere that fosters lasting wellness and sobriety.

Arizona Recovery Center
+9 photos

Arizona Recovery Center

Lake Havasu City, AZ

Located in Lake Havasu City, AZ, Arizona Recovery Center provides outpatient detox and substance use treatment for adults, children, adolescents, and active-duty military personnel. The facility has a strong emphasis on anger management, brief intervention, and cognitive behavioral therapy. Clients who have faced trauma, intimate partner violence, or domestic violence can expect customized care designed to meet their specific needs. The center focuses on individualized treatment, offering outpatient options such as methadone, buprenorphine, or naltrexone therapy for both males and females. With a dedicated team of professionals and a wide range of comprehensive programs, Arizona Recovery Center ensures that those seeking addiction treatment receive high-quality care in a nurturing environment.

CleanSlate Centers
+9 photos

CleanSlate Centers

Tewksbury, MA

CleanSlate Centers, located in Tewksbury, MA, specializes in outpatient treatment for substance use, prioritizing personalized care for adults and young adults alike. They provide options such as outpatient methadone, buprenorphine, and naltrexone treatment. The center employs techniques like motivational interviewing, relapse prevention strategies, and counseling for substance use disorders to aid in the recovery process. With programs specifically designed to meet the unique needs of each client, CleanSlate ensures that every individual receives tailored support throughout their treatment. Additionally, this facility is equipped to serve both male and female clients, offering high-quality care in a nurturing environment. As a result, CleanSlate Centers in Tewksbury stands out as a great option for anyone in search of effective and thorough addiction treatment services.

Truman Medical Center Behav Hlth
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Truman Medical Center Behav Hlth

Kansas City, MO

Truman Medical Center Behav Hlth, located in Kansas City, MO, offers tailored programs specifically designed for substance use treatment. The center features a variety of options including intensive outpatient treatment, outpatient services, and regular outpatient care. By employing evidence-based methods such as brief intervention, cognitive behavioral therapy, and contingency management with motivational incentives, this facility effectively supports adult men and women, as well as individuals who have faced domestic or intimate partner violence. Catering to both adults and young adults of all genders, Truman Medical Center Behav Hlth is committed to providing quality care and comprehensive support for those on the path to recovery from substance use disorders.

Recovery Works Healing Center LLC
+9 photos

Recovery Works Healing Center LLC

Dayton, OH

Recovery Works Healing Center LLC, located in Dayton, OH, provides targeted treatment for detoxification, substance use issues, and co-occurring mental health conditions in adults, as well as emotional challenges in children. The center features both intensive outpatient and outpatient detoxification programs that incorporate evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and anger management. Their offerings are designed to meet the specific needs of both adults and young adults, regardless of gender. By emphasizing personalized care, Recovery Works Healing Center fosters a supportive and comprehensive environment for individuals looking to achieve effective rehabilitation services.

Newport Academy
+9 photos

Newport Academy

Orange, CA

Nestled in Orange, CA, Newport Academy is dedicated to helping individuals facing challenges related to substance use and co-occurring mental health issues. This facility offers a wide array of rehabilitation services, including intensive outpatient programs, long-term residential care, and outpatient treatment options specially designed for adults, children, adolescents, and young adults. Emphasizing therapeutic methods such as anger management, cognitive behavioral therapy, and motivational interviewing, Newport Academy strives to deliver high-quality support for those navigating trauma, dual diagnoses, and emotional disturbances. The center prides itself on its specialized programs, which cater to both male and female clients, fostering a welcoming and inclusive atmosphere for all on their journey to recovery.

Recovery Works
+9 photos

Recovery Works

Martinsville, IN

Recovery Works, situated in Martinsville, IN, offers a wide array of addiction treatment services designed to help individuals on their road to recovery. The center features detoxification, substance use treatment, transitional housing, and sober living options. With various treatment formats such as intensive outpatient, long-term residential, and outpatient programs, Recovery Works is equipped to meet a range of individual needs. To ensure personalized care, the facility employs several therapeutic approaches, including 12-step facilitation, anger management, and cognitive behavioral therapy. Additionally, there are specialized programs tailored for active duty military personnel, as well as options for adult men and women. Committed to serving adults and young adults of all genders, Recovery Works focuses on providing high-quality, evidence-based treatment aimed at achieving lasting recovery.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • •Tolerance development requiring escalating doses for the same effect
  • •Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • •Genetic predisposition to addiction
  • •Mental health conditions that drive medication misuse
  • •Doctor shopping and obtaining multiple prescriptions
  • •Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab