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Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

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Showing 20 of 8160 prescription drug abuse rehab centers

Community Health Connections Inc
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Community Health Connections Inc

Fitchburg, MA

Situated in Fitchburg, MA, Community Health Connections Inc delivers a wide range of outpatient treatment options for both adults and children grappling with co-occurring serious mental health conditions. The facility is dedicated to serving individuals diagnosed with HIV/AIDS, those facing both mental health and substance use disorders, as well as those dealing with pain alongside substance use issues. Emphasizing cognitive behavioral therapy and community reinforcement strategies, the center also provides outpatient treatment with methadone, buprenorphine, or naltrexone. Catering to adults and seniors of all genders, the center takes pride in offering personalized care and support to those on the journey to recovery from addiction and mental health hurdles.

MFI Recovery Center
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MFI Recovery Center

Riverside, CA

MFI Recovery Center, located in Riverside, CA, specializes in providing substance use treatment for adult men, seniors, and young adults within a nurturing residential environment. The center offers a variety of programs designed to support those dealing with co-occurring substance use and serious mental health issues, as well as addressing emotional disturbances in children. Their approach combines 12-step facilitation, anger management, and brief intervention strategies to effectively meet the unique needs of each client. Additionally, MFI Recovery Center features special programs tailored for individuals who have faced intimate partner violence, domestic violence, or sexual abuse, ensuring that each recovery journey is comprehensive and personalized. At this well-respected rehabilitation facility, you can expect high-quality care and committed support.

Malcolm Randall VAMC
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Malcolm Randall VAMC

Gainesville, FL

Situated in Gainesville, FL, the Malcolm Randall VAMC provides a wide range of rehabilitation services for adults and seniors facing challenges with substance use disorders along with co-occurring mental health issues. Here, you’ll find intensive outpatient treatment options, outpatient detoxification, and various outpatient programs that employ techniques including 12-step facilitation, anger management, and brief interventions. The facility also features specialized programs designed for active duty military, as well as distinct offerings for adult men and women. Every patient receives personalized care, carefully crafted to meet their specific needs. With a commitment to inclusivity, the center serves both male and female clients, fostering a supportive environment for everyone on their journey to recovery.

College Recovery LLC
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College Recovery LLC

New Brunswick, NJ

Located in New Brunswick, NJ, College Recovery LLC provides a wide array of substance use treatment programs tailored for both adults and young adults. The center is particularly adept at addressing co-occurring substance use disorders along with serious mental health issues in adults, as well as significant emotional disturbances in children. With options like intensive outpatient, outpatient, and day treatment, clients can benefit from various approaches, including 12-step facilitation, anger management, and brief interventions. At College Recovery LLC, care is personalized to meet the distinct needs of each individual. They work with adult men, adult women, and clients who have faced sexual abuse, emphasizing individualized support. This commitment to high-quality care positions the center as an excellent option for those in search of effective and compassionate treatment.

MidState Health Center
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MidState Health Center

Bristol, NH

MidState Health Center, located in Bristol, NH, provides a wide range of substance use treatment options for both adults and young adults through their outpatient programs. They offer various services such as outpatient treatment with methadone, buprenorphine, or naltrexone, regular outpatient care, brief interventions, cognitive behavioral therapy, and contingency management using motivational incentives. The facility has a particular focus on supporting pregnant and postpartum women, while also delivering customized assistance for both male and female clients. By emphasizing personalized care and evidence-based methods, MidState Health Center is dedicated to delivering top-notch treatment for individuals looking for help with addiction.

East Valley Integrated Health Home
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East Valley Integrated Health Home

Mesa, AZ

Situated in Mesa, AZ, East Valley Integrated Health Home provides outpatient treatment for adults and young adults struggling with substance use issues alongside mental health challenges. This center excels in a variety of therapeutic techniques, including brief intervention, cognitive behavioral therapy, and motivational interviewing, ensuring that each individual receives personalized and effective care. Welcoming both male and female clients, the facility places a strong emphasis on addressing co-occurring mental health and substance use disorders. Through its holistic approach and tailored programs designed for various age groups, East Valley Integrated Health Home is committed to supporting clients on their journey toward lasting recovery and overall wellness.

Tallahassee Outpatient Annex
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Tallahassee Outpatient Annex

Tallahassee, FL

Situated in Tallahassee, FL, the Tallahassee Outpatient Annex specializes in outpatient treatments for adults and children facing substance use issues alongside co-occurring mental health conditions. With an emphasis on techniques such as cognitive behavioral therapy, motivational interviewing, and brief interventions, the facility offers intensive outpatient programs and various outpatient services, including methadone, buprenorphine, or naltrexone treatments. Additionally, the center has customized programs available for veterans, serving adults and young adults of all genders. The Tallahassee Outpatient Annex is committed to providing exceptional care to those in need of comprehensive rehabilitation services within a nurturing environment.

Recovery Institute of Ohio
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Recovery Institute of Ohio

Sandusky, OH

Situated in Sandusky, OH, the Recovery Institute of Ohio provides a wide range of services for substance use treatment. They specialize in transitional housing and are equipped to handle co-occurring substance use and serious mental health issues in adults, as well as emotional disturbances in children. This facility offers both hospital inpatient and intensive outpatient programs, emphasizing approaches such as 12-step facilitation, anger management, and brief interventions. There are customized programs specifically designed for adult men, women, and individuals who have faced trauma. Catering to adults and young adults of all genders, the center is committed to delivering high-quality care and support to those on their journey to recovery and healing.

Canyonlands Healthcare
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Canyonlands Healthcare

Globe, AZ

Canyonlands Healthcare, situated in Globe, AZ, offers outpatient substance use treatment specifically designed for adult and senior males. The facility features specialized programs including anger management, brief intervention, and cognitive behavioral therapy. Committed to providing personalized care, Canyonlands tailors treatment plans to fit the unique needs of each individual. Their services encompass outpatient methadone/buprenorphine or naltrexone treatments, regular outpatient care, all while prioritizing high-quality support. If you or someone you know is looking for a comprehensive addiction treatment program in a nurturing environment, Canyonlands Healthcare may be the perfect choice to assist in your recovery journey.

Peaks Recovery Centers
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Peaks Recovery Centers

Colorado Springs, CO

Peaks Recovery Centers, situated in Colorado Springs, CO, offers a wide range of addiction treatment options for both adults and young adults. This facility specializes in detoxification, substance use treatment, and tailored support for those facing both substance use issues and significant mental health conditions. Treatment approaches include intensive outpatient care, long-term residential programs, and outpatient services to best fit individuals' needs. The center emphasizes strategies like anger management, brief intervention, and cognitive behavioral therapy, making it an excellent choice for active duty military members as well as adult men and women. With a strong dedication to delivering high-quality care, Peaks Recovery Centers stands out as a leading choice for those seeking effective and personalized rehabilitation solutions.

Vivia Health Bucktown
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Vivia Health Bucktown

Chicago, IL

Situated in Chicago, IL, Vivia Health Bucktown provides extensive treatment for substance use disorders, along with specialized care for adults dealing with co-occurring mental health issues and for children experiencing serious emotional disturbances. The center offers a variety of treatment options, including intensive outpatient programming, outpatient services, and day treatment. Their approach incorporates effective methods such as 12-step facilitation, anger management, and brief intervention strategies. Additionally, they have customized programs for active duty military personnel, as well as for adult men and women. Catering to adults and young adults of all genders, Vivia Health Bucktown is dedicated to delivering high-quality, evidence-based care to help individuals on their journey toward recovery.

Creek Nation Behavioral Health
+9 photos

Creek Nation Behavioral Health

Okemah, OK

Situated in Okemah, OK, Creek Nation Behavioral Health provides outpatient treatment for substance use and offers specialized care for adults struggling with co-occurring substance use disorders and serious mental health issues, as well as emotional challenges in children. By employing techniques such as brief intervention, cognitive behavioral therapy, and motivational interviewing, this facility is committed to creating individualized programs that meet the unique needs of each client. Catering to both adults and children/adolescents of all genders, Creek Nation Behavioral Health adopts a comprehensive and gender-sensitive approach to treatment. With an emphasis on delivering quality care and personalized support, this center is devoted to assisting individuals on their path to recovery.

Family Medicine and Rehab Center
+9 photos

Family Medicine and Rehab Center

Knightdale, NC

The Family Medicine and Rehab Center, located in Knightdale, NC, specializes in outpatient treatment for both substance use and co-occurring mental health issues in adults and children. This facility offers a variety of programs designed specifically for active duty military personnel and adult men and women, ensuring comprehensive care for individuals of all ages. To facilitate a holistic recovery experience, the center employs various methods, including 12-step facilitation, anger management, and brief interventions. Clients have access to outpatient treatments like methadone, buprenorphine, or naltrexone, as well as regular outpatient services. Committed to providing top-quality care and personalized treatment plans, the center is focused on guiding clients toward their wellness goals.

449 Recovery
+9 photos

449 Recovery

Mission Viejo, CA

Situated in Mission Viejo, CA, 449 Recovery is dedicated to providing tailored substance use treatment for adults facing serious mental health challenges or emotional issues in children. The center offers a range of services, including intensive outpatient treatment, outpatient day treatment, and partial hospitalization. Emphasizing methods like 12-step facilitation, anger management, and brief intervention strategies, the facility serves both adult men and women, including those who have dealt with intimate partner or domestic violence. By accommodating clients from all backgrounds, this center ensures personalized care and support for adults and young adults in need of thorough rehabilitation services within a safe and nurturing setting.

Addiction Recovery Care (ARC)
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Addiction Recovery Care (ARC)

Louisa, KY

Addiction Recovery Care (ARC), situated in Louisa, KY, is dedicated to delivering a full range of substance use treatment specifically for female adults, seniors, and young adults. The center features various programs, including intensive outpatient, long-term residential, and outpatient options, all centered around 12-step facilitation, anger management, and brief intervention techniques. What sets ARC apart are its customized treatment plans, thoughtfully designed to meet the individual needs of each client. With a strong commitment to providing high-quality care, this facility fosters a nurturing environment for those on their journey to addiction recovery. If you're seeking personalized and effective treatment alternatives, ARC's specialized services might be exactly what you need.

Spring Gardens Recovery
+9 photos

Spring Gardens Recovery

Spring Hill, FL

Spring Gardens Recovery, situated in Spring Hill, FL, provides a wide array of rehabilitation services designed for adults and young adults who are facing substance use disorders alongside co-occurring mental health issues. The center features residential detoxification, 24-hour residential care, and short-term residential programs that cater to each person's unique needs. Emphasizing evidence-based practices such as cognitive behavioral therapy and anger management, the facility also has specialized programs tailored for active duty military members, as well as adult men and women. Committed to delivering quality care within a nurturing environment, Spring Gardens Recovery aims to support individuals on their journey towards lasting recovery and enhanced mental wellness.

Restore Health and Wellness Center LLC
+9 photos

Restore Health and Wellness Center LLC

Canoga Park, CA

Located in Canoga Park, CA, Restore Health and Wellness Center LLC is dedicated to delivering comprehensive substance use treatment for both adults and young adults. They offer a variety of treatment options, including intensive outpatient programs, standard outpatient care, and outpatient day treatment. At this center, you'll find a strong emphasis on 12-step facilitation, anger management, and brief intervention strategies, allowing them to customize programs to fit individual needs effectively. They specialize in assisting clients who have faced trauma as well as those dealing with co-occurring mental health and substance use disorders. Restore Health and Wellness Center LLC also provides gender-specific care for both men and women. With a commitment to delivering high-quality care, the center supports individuals throughout their recovery journey with tailored treatment plans and a nurturing environment.

Saint Joseph Institute
+9 photos

Saint Joseph Institute

Port Matilda, PA

Situated in Port Matilda, PA, Saint Joseph Institute provides an extensive array of rehabilitation services aimed at both adults and young adults. The facility excels in detoxification and treatment for substance use and co-occurring disorders. They offer both residential and short-term residential programs that emphasize 12-step facilitation, anger management, and brief interventions. Saint Joseph Institute also features specialized programs designed for active-duty military personnel as well as programs tailored for adult men and women. With their commitment to quality care and personalized approaches, it's no wonder that this institution is a preferred option for those looking for effective treatment for addiction and mental health challenges.

Monterey Bay Recovery and Rehab
+9 photos

Monterey Bay Recovery and Rehab

Aptos, CA

Monterey Bay Recovery and Rehab, located in Aptos, CA, provides a range of services including intensive outpatient treatment, outpatient options, and day treatment specifically for substance use issues. They have crafted specialized programs designed for adult men and women, including those who have faced trauma. Emphasizing techniques such as 12-step facilitation, anger management, and brief interventions, the center focuses on delivering personalized care to adults and young adults, regardless of gender. With a well-rounded approach and customized programs, they aim to offer high-quality support for individuals on their path to recovery from addiction. If you're searching for a nurturing environment that understands and addresses your specific needs, this facility might be an excellent choice for your rehabilitation journey.

Design for Change
+9 photos

Design for Change

Lancaster, CA

Situated in Lancaster, CA, "Design for Change" delivers a wide range of addiction treatment services tailored for both adults and young adults. Here, you can find long-term residential programs, residential detoxification, and round-the-clock residential care. The center emphasizes 12-step facilitation, anger management, and brief interventions, specifically designed for individuals grappling with co-occurring substance use and serious mental health disorders. Moreover, "Design for Change" provides specialized programs aimed at active duty military personnel, as well as programs tailored for adult men and women. With custom care provided for each gender, this facility is committed to offering exceptional treatment for those on their journey to recovery from substance abuse and mental health issues.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • •Tolerance development requiring escalating doses for the same effect
  • •Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • •Genetic predisposition to addiction
  • •Mental health conditions that drive medication misuse
  • •Doctor shopping and obtaining multiple prescriptions
  • •Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab