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Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

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Showing 20 of 8160 prescription drug abuse rehab centers

Deer Hollow Recovery
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Deer Hollow Recovery

Draper, UT

Deer Hollow Recovery, situated in Draper, UT, provides a thorough approach to substance use treatment catering to both adults and young adults. The facility offers various programs, such as intensive outpatient, long-term residential, and outpatient services, specifically designed to address the needs of clients dealing with trauma and co-occurring disorders. By incorporating evidence-based methods like 12-step facilitation, cognitive behavioral therapy, and motivational interviewing, the center customizes its treatment plans to suit each individual. Welcoming clients of all genders, Deer Hollow Recovery fosters a supportive and inclusive atmosphere. Here, you'll find compassionate care that leads to effective recovery at this esteemed rehabilitation center.

First Hospital Panamericano
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First Hospital Panamericano

Cidra, PR

First Hospital Panamericano, located in Cidra, PR, specializes in inpatient detoxification and treatment for substance use issues, as well as co-occurring mental health disorders. This facility is dedicated to providing comprehensive support not just for adults facing serious mental health challenges but also for children dealing with emotional disturbances. Their approach relies on evidence-based methods, including 12-step facilitation, anger management, and brief interventions, all designed to foster recovery. The center offers unique programs specifically tailored for active duty military members, adolescents, and adult men, recognizing the diverse needs of its patients. By serving both males and females from various age groups, this facility places a strong emphasis on delivering high-quality care and personalized treatment, all aimed at facilitating lasting healing and wellness.

Weeks Medical Center
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Weeks Medical Center

Lancaster, NH

Situated in Lancaster, NH, Weeks Medical Center provides a wide array of outpatient substance use treatment services for adults. The facility also specializes in addressing co-occurring substance use and serious mental health issues in adults, as well as serious emotional disturbances in children and adolescents. At Weeks Medical Center, patients can access outpatient treatments involving methadone, buprenorphine, or naltrexone, along with regular outpatient services. There are various therapeutic approaches available, such as 12-step facilitation, anger management, and brief interventions. Prioritizing personalized care, the center serves both male and female clients, ensuring that each individual receives quality treatment specifically aligned with their unique needs and situations.

Sanative Recovery and Wellness
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Sanative Recovery and Wellness

Cincinnati, OH

Located in Cincinnati, OH, Sanative Recovery and Wellness provides a wide range of substance use treatment services, along with specialized support for those facing co-occurring mental health issues. The facility features various options, including intensive outpatient programs, outpatient day treatment, and partial hospitalization. With an emphasis on 12-step facilitation, anger management, and brief intervention techniques, they serve both adult men and women, as well as clients who have endured trauma. Welcoming adults and young adults of all genders, Sanative Recovery and Wellness is committed to offering high-quality, individualized care to help individuals navigate their recovery journey.

Sunrise Treatment Center
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Sunrise Treatment Center

Springfield, OH

Sunrise Treatment Center, situated in Springfield, OH, provides a wide array of addiction treatment services aimed at both adults and young adults. This facility offers intensive outpatient treatment, outpatient detoxification, and personalized outpatient programs designed to meet individual needs. They excel in areas such as anger management, brief intervention, and cognitive behavioral therapy. Their unique offerings also include programs specifically designed for adult men and women, as well as for clients dealing with co-occurring mental health and substance use disorders. Committed to delivering high-quality care, Sunrise Treatment Center is passionate about supporting both male and female clients on their path to recovery.

MedMark Treatment Centers
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MedMark Treatment Centers

Sacramento, CA

MedMark Treatment Centers, located in Sacramento, CA, is dedicated to providing outpatient services that focus on detoxification and the treatment of substance use disorders. The center employs a variety of therapeutic techniques, including cognitive behavioral therapy, contingency management, and the Matrix Model, to ensure that patients receive personalized care tailored to their specific needs. They offer outpatient detoxification alongside treatment options such as methadone, buprenorphine, or naltrexone, allowing them to support a diverse range of clients. MedMark’s commitment to an individualized approach sets it apart, as they create customized treatment plans for each person, whether they are adults, children, or adolescents. Catering to both males and females, the center emphasizes quality care, grounded in evidence-based practices. If you or someone you care about is looking for effective addiction treatment in Sacramento, MedMark Treatment Centers may be a great option to consider.

AppleGate Recovery
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AppleGate Recovery

Bossier City, LA

AppleGate Recovery, located in Bossier City, LA, provides outpatient treatment for substance use, catering to both adults and young adults, including those facing serious mental health challenges alongside their addiction. With tailored programs designed specifically for women and men, this facility emphasizes personalized care through techniques such as cognitive behavioral therapy, motivational interviewing, and strategies for preventing relapse. Their outpatient services also include methadone/buprenorphine and naltrexone treatment, all grounded in a commitment to an individualized approach. If you're looking for top-notch addiction treatment that feels personal and supportive, AppleGate Recovery is here to assist individuals on their journey to lasting recovery.

Rosecrance Jackson Centers
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Rosecrance Jackson Centers

Sioux City, IA

Located in Sioux City, IA, Rosecrance Jackson Centers provides long-term residential treatment for adult women dealing with substance use issues alongside mental health disorders. This facility features transitional housing and offers round-the-clock care. Their treatment methods include 12-step facilitation and cognitive behavioral therapy. With specialized programs designed for individuals with co-occurring disorders, as well as personalized treatment options for adults, seniors, and young adults, this center is committed to delivering high-quality care in a nurturing environment. If you’re in search of comprehensive addiction treatment that places a strong emphasis on mental health, Rosecrance Jackson Centers could be exactly what you need.

Elm Tree Clinic
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Elm Tree Clinic

Quincy, MA

Elm Tree Clinic, located in Quincy, MA, provides outpatient treatment for substance use and care for co-occurring disorders aimed at both adults and children. Their comprehensive approach features relapse prevention strategies, counseling sessions, and telemedicine therapy options. By offering specialized individual programs, the clinic ensures that both adults and young adults receive care that aligns with their specific needs. In addition, they provide outpatient services that include methadone, buprenorphine, or naltrexone treatment, making sure clients have access to the support they need. Plus, Elm Tree Clinic has gender-specific programs tailored for males and females, creating a nurturing environment for everyone. Experience high-quality care and personalized treatment at this facility that is committed to helping individuals on their journey toward lasting recovery.

Cenikor Foundation
+5 photos

Cenikor Foundation

Farmington, NM

Nestled in Farmington, NM, the Cenikor Foundation delivers a wide array of addiction treatment services designed for both adults and young adults. This center features residential detoxification, around-the-clock residential care, and short-term residential programs tailored for those on the path to recovery from substance use disorders and co-occurring mental health issues. Employing evidence-based methods including 12-step facilitation, anger management techniques, and cognitive behavioral therapy, Cenikor Foundation carefully customizes treatment plans to meet the specific needs of each individual. With a strong emphasis on personalized care, the facility also provides specialized programs that cater to the distinct challenges faced by men and women alike. Discover compassionate care and supportive services at the Cenikor Foundation.

Rosecrance Jackson Centers
+5 photos

Rosecrance Jackson Centers

Sioux City, IA

Located in Sioux City, IA, Rosecrance Jackson Centers provides a wide array of addiction treatment services for both adults and children. This facility specializes in detoxification, substance use treatment, and offers targeted support for those grappling with co-occurring substance use disorders as well as serious mental health issues. Emphasizing intensive outpatient care and outpatient detoxification, the center employs evidence-based methods, including 12-step facilitation, brief intervention, and cognitive behavioral therapy. Customized programs cater specifically to adolescents, adult men, and adult women. Rosecrance Jackson Centers is committed to delivering high-quality, personalized care for adults and seniors of all genders, aiming to foster lasting recovery.

Bear River Health Department
+5 photos

Bear River Health Department

Logan, UT

Bear River Health Department, based in Logan, UT, specializes in substance use treatment designed for adults facing co-occurring mental health issues, as well as serious emotional disturbances in children. The center offers a variety of programs, including intensive outpatient options and general outpatient services. They also provide treatment with methadone/buprenorphine or naltrexone. Emphasizing the benefits of 12-step facilitation, anger management, and brief intervention techniques, this facility serves a diverse range of clients, including adolescents, adult men and women, seniors, and individuals of all gender identities. With personalized programs and high-quality care, Bear River Health Department stands out as an excellent option for anyone in the Logan area looking for comprehensive rehabilitation services.

Heron Ridge Associated PLC
+5 photos

Heron Ridge Associated PLC

Franklin, MI

Located in Franklin, MI, Heron Ridge Associated PLC specializes in outpatient substance use treatment for both adults and children/adolescents. The facility employs a range of techniques, including anger management, cognitive behavioral therapy, and counseling for substance use disorders, offering personalized care tailored to each individual's specific needs. With a commitment to providing high-quality support, the center ensures that clients of all genders receive the specialized attention they deserve. This regular outpatient treatment format allows individuals to continue with their daily lives while still accessing essential support. For those in search of effective and customized addiction treatment services in Franklin, Heron Ridge Associated PLC stands out as a dependable option.

Spero Health
+5 photos

Spero Health

Marietta, OH

Spero Health, situated in Marietta, OH, delivers a wide range of substance use treatment options, including intensive outpatient, outpatient, and programs featuring methadone, buprenorphine, or naltrexone. The center has a strong emphasis on specialized services such as anger management, brief interventions, and cognitive behavioral therapy. They offer tailored programs specifically designed for adult men and women, as well as for individuals who have faced intimate partner or domestic violence. This facility serves adults and young adults of all genders, fostering a nurturing atmosphere for those on their journey to recovery. With a commitment to personalized care and evidence-based practices, Spero Health in Marietta is devoted to supporting clients in achieving long-term sobriety and improving their overall well-being.

INSPIRA Behavioral Care Corp
+5 photos

INSPIRA Behavioral Care Corp

Caguas, PR

INSPIRA Behavioral Care Corp, located in Caguas, PR, offers a variety of outpatient treatment options designed for both adults and children/adolescents dealing with substance use issues and co-occurring mental health conditions. This facility provides specialized services for different groups, including active duty military personnel, adolescents, and adult men, ensuring a well-rounded approach to recovery. The center employs evidence-based practices, such as cognitive behavioral therapy, anger management techniques, and brief interventions, to deliver customized care tailored to each individual's needs. Whether individuals are looking for outpatient day treatment, partial hospitalization, or medication-assisted treatment, they can expect high-quality care that is specific to their gender. What sets INSPIRA Behavioral Care Corp apart is its dedication to offering effective, personalized rehabilitation services within a nurturing environment.

Samaritas
+5 photos

Samaritas

Troy, MI

Samaritas, situated in Troy, MI, stands out as a leading rehabilitation center that offers a wide array of treatment options for those struggling with substance use disorders. The facility is particularly adept at addressing co-occurring substance use issues alongside severe mental health challenges in adults, while also supporting children with significant emotional disturbances. Samaritas emphasizes both intensive outpatient and outpatient programs, employing various specialized care techniques. These include anger management, brief intervention strategies, and cognitive behavioral therapy. The center tailors its programs to meet the unique needs of adolescents, adults, and seniors of all genders, ensuring that each individual receives a personalized treatment plan. Committed to excellence, Samaritas strives to provide high-quality care and unwavering support for those on their journey to recovery from addiction.

Arbor Counseling Center
+5 photos

Arbor Counseling Center

Buffalo Grove, IL

Located in Buffalo Grove, IL, Arbor Counseling Center provides outpatient treatment for substance use, along with specialized care for adults dealing with both substance use and serious mental health issues. They also support children facing emotional disturbances. The center utilizes methods such as cognitive behavioral therapy, substance use disorder counseling, and offers telemedicine services for added convenience. With an emphasis on personalized care, Arbor Counseling Center serves adults and seniors from all gender identities. Their dedication to high-quality care and customized treatment plans positions them as a reliable option for individuals in search of thorough and effective rehabilitation services.

Advocates Community Counseling
+5 photos

Advocates Community Counseling

Harvard, MA

Located in Harvard, MA, Advocates Community Counseling specializes in outpatient treatment for substance use and offers support for adults facing serious mental health challenges, as well as children experiencing significant emotional disturbances. The center provides consistent outpatient services that include anger management, cognitive behavioral therapy, and motivational interviewing. By prioritizing individualized care, Advocates Community Counseling serves adults and seniors of all genders, creating a welcoming atmosphere for all. What sets this facility apart is its commitment to personalized treatment, ensuring every client receives the tailored support they need. If you’re in search of effective addiction treatment in a nurturing setting, this facility is dedicated to providing evidence-based therapies to aid your recovery journey.

Healthcare Resource Centers
+5 photos

Healthcare Resource Centers

Greenfield, MA

Healthcare Resource Centers, located in Greenfield, MA, provides a range of services including outpatient detoxification, substance use treatment, and outpatient options for methadone, buprenorphine, or naltrexone. Their comprehensive programs feature anger management, brief intervention, and cognitive behavioral therapy to support clients effectively. This facility is equipped to offer specialized services for adult men and women, as well as individuals who have faced intimate partner or domestic violence. Catering to adults and young adults of all genders, Healthcare Resource Centers is committed to delivering high-quality care that is customized to meet individual needs. If you or someone you care about is looking for addiction treatment that emphasizes personalized care and specialized programs, this Greenfield center is here to assist you on your path to recovery.

Addiction Recovery Care (ARC)
+5 photos

Addiction Recovery Care (ARC)

Louisville, KY

Situated in Louisville, KY, Addiction Recovery Care (ARC) specializes in treating substance use disorders for both adults and young adults. The center offers an extensive array of services, which encompasses intensive outpatient treatment, outpatient programs, and partial hospitalization or outpatient day treatment. ARC employs evidence-based methods that include 12-step facilitation, anger management techniques, and brief interventions. With a strong emphasis on personalized care, this facility serves both men and women. What sets ARC apart is its dedication to delivering quality treatment and customized programs that are designed to meet the unique needs of each client, making it a trusted option for anyone looking for effective addiction recovery solutions.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • •Tolerance development requiring escalating doses for the same effect
  • •Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • •Genetic predisposition to addiction
  • •Mental health conditions that drive medication misuse
  • •Doctor shopping and obtaining multiple prescriptions
  • •Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab