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Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

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Showing 20 of 8160 prescription drug abuse rehab centers

Cass County Community Mental Hlth

Cass County Community Mental Hlth

Cassopolis, MI

Situated in Cassopolis, MI, Cass County Community Mental Health delivers a variety of specialized treatment programs designed for adults and seniors grappling with substance use challenges and co-occurring serious mental health disorders. The center offers a range of options, including intensive outpatient, outpatient, and regular outpatient treatments, all grounded in evidence-based practices such as cognitive behavioral therapy, contingency management, and the Matrix Model. Emphasizing trauma-informed care, the facility provides customized programs for adult men, adult women, and clients who have faced traumatic experiences. By offering personalized support for both male and female clients, this center is committed to delivering high-quality and comprehensive rehabilitation services, guiding individuals along their path to recovery.

Oklahoma Treatment Services

Oklahoma Treatment Services

Ponca City, OK

Situated in Ponca City, Oklahoma, Treatment Services provides tailored outpatient programs specifically for adults and young adults dealing with substance use issues. The facility offers various treatment options, such as outpatient methadone/buprenorphine or naltrexone treatments, regular outpatient care, and brief intervention sessions. Emphasizing cognitive behavioral therapy and motivational interviewing, this center prioritizes personalized care for each individual. They also have specialized programs designed for active duty military members, as well as distinct services for adult men and women. With a strong commitment to delivering quality care, Oklahoma Treatment Services is open to individuals of all genders who are seeking effective and compassionate addiction treatment.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Mooresville, IN

Located in Mooresville, IN, Centerstone of Indiana Inc specializes in outpatient substance use treatment and offers targeted care for individuals facing both substance use issues and significant mental health conditions. The facility features regular outpatient programs that incorporate a variety of techniques, including anger management, brief intervention, and cognitive behavioral therapy. Additionally, they have specialized programs designed for adolescents, adult men, and adult women, accommodating a wide spectrum of clients. Catering to both adults and seniors across genders, Centerstone of Indiana Inc is committed to delivering high-quality care and extensive support for individuals aiming to overcome addiction and mental health obstacles.

Margaret Mary Health

Margaret Mary Health

Osgood, IN

Situated in Osgood, IN, Margaret Mary Health provides a range of specialized treatment programs for substance use, catering to both adults and seniors. The center features intensive outpatient treatment along with outpatient services, including options for methadone, buprenorphine, or naltrexone therapy. By incorporating cognitive behavioral therapy and leveraging telemedicine and telehealth, the facility customizes treatment plans to meet the unique needs of each individual. With a commitment to personalized care, Margaret Mary Health serves both male and female clients. If you or someone you care about is in need of comprehensive addiction treatment in a nurturing environment, this center's evidence-based practices and tailored programs can offer the vital support needed for recovery.

Newport Academy

Newport Academy

Kirkland, WA

Situated in Kirkland, WA, Newport Academy provides extensive treatment for substance use, addressing both adults and children who are also dealing with mental health challenges. This facility offers a variety of options including intensive outpatient, long-term residential, and standard outpatient programs. They focus on specialized areas such as anger management, cognitive behavioral therapy, and motivational interviewing. Newport Academy features tailored programs designed for adolescents, survivors of trauma, and individuals with dual diagnoses. Welcoming clients of all ages, regardless of gender, this center emphasizes personalized care alongside evidence-based techniques aimed at fostering sustainable recovery. If you’re in search of dependable rehabilitation services in the Kirkland region, Newport Academy is committed to guiding you towards achieving long-lasting wellness.

Salvation Army Harbor Light Center

Salvation Army Harbor Light Center

Monroe, MI

Situated in Monroe, MI, the Salvation Army Harbor Light Center provides an array of thorough rehabilitation services. The facility offers detoxification, substance use treatment, transitional housing, and options for halfway houses or sober living. Catering to adults and young adults of all genders, the center features multiple treatment formats, including intensive outpatient, long-term residential, and outpatient programs. Additionally, the center has specialized programs aimed at adult men, adult women, and individuals who have faced intimate partner violence or domestic violence. To deliver personalized care and support, the center employs a variety of methodologies, including 12-step facilitation, anger management techniques, and brief intervention strategies.

Florence Treatment Specialists

Florence Treatment Specialists

Florence, SC

Florence Treatment Specialists, situated in Florence, SC, provides a wide range of outpatient substance use treatment options for both adults and young adults. The center focuses on outpatient care using methadone, buprenorphine, or naltrexone, emphasizing brief interventions, motivational interviewing, and effective relapse prevention strategies. They offer customized programs catered to adult men and women, including individuals who have faced intimate partner violence or domestic violence. By adopting a gender-specific approach and delivering personalized care, Florence Treatment Specialists is dedicated to offering high-quality treatment in a supportive and inclusive setting for those looking to recover from substance use disorders.

Drug Alternative Program Alabama

Drug Alternative Program Alabama

Huntsville, AL

Drug Alternative Program Alabama, located in Huntsville, AL, provides specialized treatment for substance use within a long-term residential environment. The facility offers 24/7 care and incorporates various therapeutic methods, including anger management, motivational interviewing, and contingency management with motivational incentives. Primarily focused on adult men, this program serves a range of clients, from young adults to seniors. Tailored specifically to male participants, the center fosters a supportive atmosphere that promotes effective recovery. Those searching for a comprehensive, gender-specific approach to treatment will find valuable care and customized programs at Drug Alternative Program Alabama.

Martinsburg Institute

Martinsburg Institute

Martinsburg, WV

Situated in Martinsburg, WV, the Martinsburg Institute provides extensive outpatient rehabilitation services aimed at helping adults and young adults who are struggling with substance use disorders. The center is dedicated to detoxification and offers specialized treatments for substance use, including outpatient options for methadone, buprenorphine, or naltrexone. Employing evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and brief interventions, the facility tailors its approach to meet the unique needs of adult men, women, pregnant and postpartum women, as well as individuals of all gender identities. Committed to delivering high-quality care and personalized treatment plans, the Martinsburg Institute strives to support each client throughout their recovery journey.

ALTR of Jackson LLC

ALTR of Jackson LLC

Jackson, MS

Located in Jackson, MS, ALTR of Jackson LLC provides outpatient substance use treatment specifically designed for adults and young adults. The facility features tailored programs for both adult men and women, including those who have faced trauma. Their treatment methods encompass 12-step facilitation, brief intervention, and cognitive behavioral therapy. By prioritizing quality care, this center offers outpatient options for methadone/buprenorphine or naltrexone treatment alongside standard outpatient services. ALTR of Jackson LLC serves both male and female clients, ensuring a well-rounded and personalized approach to addiction recovery in a nurturing environment for individuals seeking assistance.

CURA Inc

CURA Inc

Secaucus, NJ

CURA Inc, situated in Secaucus, NJ, provides focused substance use treatment through its long-term and 24-hour residential programs. The center emphasizes personalized care and employs a variety of methods, including 12-step facilitation, anger management, and brief interventions. Primarily serving adult men and women, CURA Inc also offers support for individuals who have faced intimate partner or domestic violence, addressing a wide range of needs. This facility welcomes adults and young adults of all genders, ensuring that each client receives tailored support. Recognized for its high-quality care and comprehensive treatment options, CURA Inc is a leading choice for anyone looking for effective and compassionate addiction recovery.

Tadiso Inc

Tadiso Inc

Pittsburgh, PA

Tadiso Inc, situated in Pittsburgh, PA, specializes in substance use treatment programs tailored for adults and young adults. The facility offers a range of outpatient services, which include day treatment, partial hospitalization, and options for methadone, buprenorphine, or naltrexone treatment. Emphasizing evidence-based methods like cognitive behavioral therapy and contingency management, Tadiso Inc is dedicated to providing high-quality, individualized care. The center also supports pregnant and postpartum women, as well as clients involved in the criminal justice system. With a strong emphasis on gender-specific services for both men and women, Tadiso Inc creates a comprehensive and nurturing environment for individuals seeking effective addiction recovery solutions.

Bowdoin Recovery Services LLC

Bowdoin Recovery Services LLC

Smyrna, TN

Located in Smyrna, TN, Bowdoin Recovery Services LLC offers a wide range of substance use treatment options for both adults and children facing co-occurring mental health challenges. The center provides various programs, including intensive outpatient, outpatient, and regular outpatient services. Their methods are grounded in evidence-based practices, featuring techniques like 12-step facilitation, anger management, and brief intervention. Bowdoin Recovery Services LLC stands out for its specialization in trauma-informed care, making it a fitting choice for individuals dealing with co-occurring disorders as well as those grappling with pain alongside substance use. By focusing on personalized treatment, this facility designs its programs to meet the unique needs of male and female clients, fostering a supportive and inclusive atmosphere for everyone on their path to recovery.

Lakeland Centres

Lakeland Centres

Lakeland, FL

Lakeland Centres, situated in Lakeland, FL, provides a wide range of substance use treatment options. Their services include outpatient care, as well as methadone/buprenorphine and naltrexone treatments, along with regular outpatient programs. The facility focuses specifically on counseling for substance use disorders, serving adult men and women, including active duty military personnel. By concentrating on adults and young adults from both genders, Lakeland Centres ensures that each client receives personalized care and support on their journey to recovery. Their customized approach and specialized programs have established them as a leading option for those in search of high-quality addiction treatment in the Lakeland area.

Newport Mental Health

Newport Mental Health

Middletown, RI

Newport Mental Health, situated in Middletown, RI, is dedicated to delivering specialized outpatient care for adults and children/adolescents struggling with substance use and co-occurring mental health issues. The center offers an array of services, such as outpatient treatment with methadone, buprenorphine, or naltrexone, along with anger management, brief intervention, and cognitive behavioral therapy. They particularly focus on supporting trauma survivors and those dealing with dual diagnoses, ensuring that both men and women can access the high-quality care they deserve in a nurturing setting. For anyone looking for help with substance use, severe mental health challenges, or emotional disturbances, Newport Mental Health designs comprehensive programs that are tailored to individual needs, fostering a path toward lasting recovery.

Centennial Peaks Hospital

Centennial Peaks Hospital

Louisville, CO

Centennial Peaks Hospital, located in Louisville, CO, provides a wide range of rehabilitation services for both adults and children struggling with substance use disorders along with co-occurring mental health issues. Their offerings include hospital inpatient detoxification and treatment programs, specifically designed to cater to active duty military personnel, as well as adult men and women. The facility emphasizes evidence-based practices such as cognitive behavioral therapy and motivational interviewing, carefully customizing treatment plans to address the distinct needs of each individual. By offering dedicated programs for adults and children, along with separate tracks for males and females, Centennial Peaks Hospital creates a welcoming and supportive atmosphere for everyone on their path to recovery.

Vitality Center

Vitality Center

Elko, NV

Vitality Center, situated in Elko, NV, provides a wide range of addiction treatment services tailored for both adults and children. The facility offers a variety of care options, including hospital inpatient services, intensive outpatient programs, and round-the-clock inpatient care specifically designed for detoxification and substance use recovery. Catering to the unique needs of different groups, Vitality Center features specialized programs for adolescents, adult men, and adult women. Their approach includes methods such as 12-step facilitation and anger management to ensure that each person receives individualized care. Additionally, the center understands the importance of addressing co-occurring mental health challenges. They provide treatment for serious mental health disorders in adults and significant emotional disturbances in children. With a strong commitment to quality care and specifically tailored interventions, Vitality Center strives to support individuals on their journey toward recovery.

Quad Cities Intervention Services

Quad Cities Intervention Services

Moline, IL

Located in Moline, IL, Quad Cities Intervention Services provides a variety of substance use treatment options tailored for adults, children, adolescents, and seniors. The center offers several levels of care, including intensive outpatient, outpatient, and regular outpatient programs. They focus on delivering individualized treatment through methods such as brief intervention, cognitive behavioral therapy, and motivational interviewing. This personalized approach ensures that each client receives care that fits their specific needs. Both men and women can take advantage of the high-quality services available at this facility. If you or someone close to you is looking for effective addiction treatment that prioritizes personal needs, Quad Cities Intervention Services is committed to supporting you on your journey to lasting recovery.

Volunteers of America Texas Inc

Volunteers of America Texas Inc

Fort Worth, TX

Located in Fort Worth, TX, Volunteers of America Texas Inc delivers a wide array of comprehensive rehabilitation services. This center offers intensive outpatient treatment, long-term residential care, and outpatient programs specifically designed for adults and young adults facing substance use disorders. They excel in addressing co-occurring substance use and serious mental health conditions. With tailored programs for adult men, adult women, and individuals with co-occurring disorders, Volunteers of America Texas Inc utilizes evidence-based methods, including 12-step facilitation, anger management, and brief interventions. Their dedication to personalized care and high-quality treatment positions them as a leading choice for those in search of effective and compassionate rehabilitation support.

Southwestern Recovery Center

Southwestern Recovery Center

The Plains, OH

Situated in The Plains, OH, Southwestern Recovery Center delivers a wide array of outpatient treatment programs designed for adults and children dealing with substance use and co-occurring mental health disorders. The center emphasizes personalized care tailored to each individual's unique needs, employing methods like 12-step facilitation, anger management, and brief interventions. With an emphasis on personal attention, Southwestern Recovery Center serves adults and young adults of all genders. In addition to regular outpatient services, the facility also offers outpatient treatment options with methadone/buprenorphine or naltrexone, demonstrating a commitment to providing high-quality support for individuals on their journey to recovery.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • Tolerance development requiring escalating doses for the same effect
  • Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • Genetic predisposition to addiction
  • Mental health conditions that drive medication misuse
  • Doctor shopping and obtaining multiple prescriptions
  • Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab