Penn Spine and Rehab Logo

Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(223) 235-7839
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 8160 prescription drug abuse rehab centers

Medical City Green Oaks Hospital

Medical City Green Oaks Hospital

Plano, TX

Medical City Green Oaks Hospital, situated in Plano, TX, offers a wide range of substance use treatment options for both adults and children/adolescents. The facility provides various treatment programs, including intensive outpatient, outpatient, and standard outpatient services. By employing methods like 12-step facilitation, anger management, and brief intervention, the center effectively addresses the needs of clients dealing with co-occurring mental health and substance use disorders. With specialized programs designed for both men and women, clients receive tailored care that meets their individual needs. Medical City Green Oaks Hospital is recognized for its commitment to high-quality care and personalized treatment plans, making it an excellent choice for those in search of effective rehabilitation services.

CLARE Matrix

CLARE Matrix

Ontario, CA

CLARE Matrix, situated in Ontario, CA, stands out as a premier rehabilitation center dedicated to addressing substance use issues. The facility offers a variety of treatment options, including intensive outpatient programs, outpatient services, and standard outpatient care, ensuring a broad spectrum of support for both adults and adolescents. Emphasizing 12-step facilitation, anger management techniques, and brief intervention strategies, CLARE Matrix tailors its approach to meet the unique needs of its clients. They provide specialized programs designed for adult men, adult women, and teenagers, ensuring that everyone receives the appropriate level of care. With a reputation for delivering high-quality support and personalized treatment plans, CLARE Matrix is a commendable option for those in search of effective addiction treatment services.

Hina Mauka/Teen Care

Hina Mauka/Teen Care

Kaneohe, HI

Hina Mauka/Teen Care, situated in Kaneohe, HI, is a respected rehabilitation center that specializes in treating substance use issues among adolescents. This facility offers outpatient services and utilizes a variety of evidence-based techniques such as contingency management, motivational interviewing, and relapse prevention. They have developed customized programs for both male and female teens, ensuring that every individual receives the thorough care they need. With an emphasis on personalized treatment and quality care, Hina Mauka/Teen Care is dedicated to supporting young people in their journey to overcome addiction and start anew.

Progress House Inc

Progress House Inc

Placerville, CA

Progress House Inc, located in Placerville, CA, provides a variety of substance use treatment services, including both outpatient and regular outpatient options. The center is dedicated to helping adult men and women, along with young adults, who have faced challenges related to intimate partner violence or domestic violence. With a strong emphasis on anger management, cognitive behavioral therapy, and motivational incentives, Progress House Inc fosters a welcoming environment for those in need of transitional housing or sober living arrangements. What sets this facility apart is its customized programs designed for specific groups, as well as its unwavering commitment to offering high-quality and effective rehabilitation services.

Community Bridges Inc

Community Bridges Inc

Mesa, AZ

Community Bridges Inc, located in Mesa, AZ, provides a wide array of substance use treatment options, all designed to meet the unique needs of each individual. They offer intensive outpatient, outpatient, and regular outpatient programs that utilize proven methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention techniques. What sets this facility apart is its dedicated programs for adolescents, as well as clients dealing with both mental health and substance use disorders, including those who experience concurrent pain issues. Community Bridges Inc serves adults as well as children and adolescents of all genders, ensuring that quality care is at the forefront of their personalized recovery approaches.

Salvation Army Lighthouse Recov Ctr

Salvation Army Lighthouse Recov Ctr

Barrigada, GU

Located in Barrigada, GU, the Salvation Army Lighthouse Recovery Center provides a thorough approach to substance use treatment. Their offerings include hospital inpatient services and 24-hour care, alongside intensive outpatient programs tailored to meet diverse needs. This center specializes in support for adult men and women, particularly those who have faced intimate partner or domestic violence. Utilizing a variety of methods like 12-step facilitation, anger management, and brief interventions, the facility serves adults and young adults across all genders. The dedication to high-quality care and customized programs positions the center as an essential resource for individuals looking for effective rehabilitation within a nurturing atmosphere.

Motivating Youth Recovery

Motivating Youth Recovery

Worcester, MA

Located in Worcester, MA, "Motivating Youth Recovery" is dedicated to providing comprehensive addiction treatment for individuals of all ages, including adults, children, and young adults. This facility offers both hospital inpatient detoxification and treatment specifically designed for substance use disorders, while also addressing co-occurring mental health issues. To support recovery effectively, the center employs evidence-based methods such as 12-step facilitation, cognitive behavioral therapy, and brief intervention. They offer specialized programs tailored for adolescents, individuals who have faced sexual abuse, and those with histories of trauma. With a strong commitment to delivering quality care, "Motivating Youth Recovery" serves both male and female clients, fostering a nurturing environment aimed at promoting lasting healing and recovery.

Lahey Health Behavioral Services

Lahey Health Behavioral Services

Lynn, MA

Located in Lynn, MA, Lahey Health Behavioral Services provides long-term and 24-hour residential treatment programs for adults dealing with substance use issues, including those affected by intimate partner violence. The facility emphasizes 12-step facilitation, anger management, and brief intervention techniques to ensure specialized care for individuals on their recovery journey. With dedicated programs for adult men, women, and young adults, the center is equipped to meet a variety of client needs. Their dedication to offering quality care and personalized treatment plans has established Lahey Health Behavioral Services as a reliable option for anyone seeking to overcome the challenges of substance use in a safe and supportive setting.

Pyramid Counseling LLC

Pyramid Counseling LLC

Beckley, WV

Located in Beckley, WV, Pyramid Counseling LLC specializes in outpatient substance use treatment for adults facing serious mental health disorders alongside their addiction issues. The facility offers regular outpatient services, employing effective strategies like 12-step facilitation, anger management, and brief intervention to support clients. They also have specialized programs designed for active-duty military members, adolescents, and adult men, ensuring that they provide comprehensive support to adults and seniors of all genders. With a commitment to quality care and personalized treatment plans, Pyramid Counseling LLC stands out as a vital resource for individuals looking to overcome addiction and mental health difficulties.

Care Crossings

Care Crossings

Stillwater, MN

Situated in Stillwater, MN, Care Crossings specializes in rehabilitation services designed for adults and seniors who face challenges related to substance use and co-occurring mental health disorders. The facility features a range of treatment options, including intensive outpatient programs, outpatient services, and standard outpatient care, all incorporating methods such as 12-step facilitation, anger management, and brief intervention strategies. While the center prioritizes support for adult women, it also provides customized care for male clients. Care Crossings stands out for its dedication to offering high-quality, personalized treatment, making it a preferred option for individuals seeking effective and comprehensive rehabilitation services in the Stillwater community.

Family Preservation Services of NC

Family Preservation Services of NC

Hendersonville, NC

Family Preservation Services of NC, located in Hendersonville, NC, provides a variety of treatment programs, including intensive outpatient, outpatient, and regular outpatient options for those facing substance use challenges and co-occurring mental health issues. The center emphasizes personalized care, utilizing methods like anger management, brief intervention, and cognitive behavioral therapy, all tailored to meet the unique needs of each individual. This facility is dedicated to supporting both adults and children/adolescents of all genders, ensuring that every client receives the specific care necessary for successful recovery. If you or someone you know is in need of comprehensive and effective treatment, you’ll find that this center offers quality care in a nurturing environment.

Southeast Kansas Mental Health Center

Southeast Kansas Mental Health Center

Pleasanton, KS

Situated in Pleasanton, KS, the Southeast Kansas Mental Health Center provides a wide range of treatment options for both substance use and co-occurring mental health conditions, catering to adults and children alike. The facility offers various outpatient services, which include anger management, brief interventions, and cognitive-behavioral therapy. What sets this center apart is its specialized programs tailored for active duty military personnel, adolescents, and adult women, addressing the unique needs of these groups. The center is committed to serving adults and seniors of every gender, ensuring that everyone receives personalized care and support. With a strong focus on high-quality, evidence-based treatment, the Southeast Kansas Mental Health Center is dedicated to helping individuals achieve effective rehabilitation outcomes.

WKDA Services LLC

WKDA Services LLC

Dresden, TN

Located in Dresden, TN, WKDA Services LLC provides extensive substance use treatment for both adults and seniors. The center specializes in outpatient services, focusing on areas such as anger management, cognitive behavioral therapy, and relapse prevention. They offer specific programs designed for adult men, adult women, and clients involved in the criminal justice system. By taking a gender-specific approach, this facility ensures that both male and female clients receive personalized care tailored to their unique needs. At WKDA Services LLC, the commitment to quality care and customized treatment plans is evident, aiming to support clients throughout their recovery journey. If you’re looking for specialized substance use treatment with a personal touch, this center is dedicated to helping you achieve lasting sobriety.

Youth Outreach Services

Youth Outreach Services

Chicago, IL

Situated in Chicago, IL, Youth Outreach Services provides outpatient treatment for substance use issues, catering to adults, children, and young adults alike. This facility is dedicated to addressing co-occurring substance use disorders along with serious mental health challenges in adults, in addition to tackling significant emotional disturbances in children. With an emphasis on anger management, cognitive behavioral therapy, and motivational interviewing, the center delivers personalized care designed to meet the distinct needs of each individual. They also feature specialized programs for adolescents, as well as for clients who have faced sexual abuse or trauma. Youth Outreach Services is open to both male and female clients in search of thorough rehabilitation support.

Windows of Discovery

Windows of Discovery

Lexington, KY

Windows of Discovery, located in Lexington, KY, provides a thorough range of substance use treatment services for individuals facing co-occurring serious mental health issues or emotional challenges. The center offers both intensive outpatient and outpatient programs, which include treatments with methadone or buprenorphine. Emphasizing 12-step facilitation, anger management, and brief interventions, this facility serves adults and young adults of all genders. They also have specialized programs that focus on issues such as intimate partner violence, domestic violence, sexual abuse, and trauma. Clients can look forward to receiving compassionate care and evidence-based treatment methods to help them on their path to recovery.

Womens Empowering Life Line Inc

Womens Empowering Life Line Inc

Norfolk, NE

At Women's Empowering Life Line Inc, located in Norfolk, NE, women looking for help can access a specialized long-term residential treatment program that addresses both substance use issues and co-occurring mental health disorders. The facility provides round-the-clock care, emphasizing 12-step facilitation, anger management, and cognitive behavioral therapy as key components of their approach. Particular attention is given to programs designed for adult women who have faced intimate partner violence, domestic violence, or sexual abuse. This center is committed to serving a variety of demographics, including adults, seniors, and young adults, creating a safe and nurturing environment for women in need of comprehensive rehabilitation. With a strong dedication to quality care and personalized treatment plans, this facility stands out as an essential resource for those seeking specialized assistance.

Alaska Family Services

Alaska Family Services

Wasilla, AK

Located in Wasilla, AK, Alaska Family Services offers an extensive array of treatment programs for substance use and co-occurring mental health issues, catering to both adults and children. The facility features a variety of options, including intensive outpatient, outpatient, and regular outpatient treatments, all designed to meet individual needs. Employing evidence-based methods such as brief intervention, cognitive behavioral therapy, and the Matrix Model, the center prioritizes high-quality care. They also provide specialized programs tailored for adult men, adult women, and clients with a history of trauma, fostering a nurturing atmosphere for everyone. Alaska Family Services is committed to supporting individuals of all genders and age groups as they work towards lasting recovery and enhanced mental well-being.

FCC Behavioral Health

FCC Behavioral Health

Kennett, MO

FCC Behavioral Health, located in Kennett, MO, delivers a wide range of outpatient rehabilitation services aimed at individuals facing challenges with substance use disorders alongside co-occurring mental health issues. The center offers tailored treatment programs specifically designed for adults dealing with severe mental health conditions and for children struggling with significant emotional challenges. Patients can access various treatment options, including outpatient services utilizing methadone, buprenorphine, or naltrexone, as well as standard outpatient care. The facility emphasizes 12-step facilitation, anger management strategies, and brief intervention techniques. FCC Behavioral Health is committed to serving active duty military members, adolescents, and adult men, and it provides compassionate care to both adults and children/adolescents of all genders. The center's mission centers around delivering high-quality, personalized support to assist clients in achieving meaningful, lasting recovery.

Comprehensive Healthcare

Comprehensive Healthcare

Pasco, WA

Situated in Pasco, WA, Comprehensive Healthcare provides a variety of specialized treatment programs designed to address substance use and co-occurring mental health conditions. The center offers several options including intensive outpatient, outpatient, and regular outpatient services, ensuring personalized care for both adults and children/adolescents. By employing evidence-based methods such as cognitive behavioral therapy and motivational interviewing, this facility effectively supports clients of all genders, with dedicated programs for adolescents and those facing co-occurring disorders. With its commitment to high-quality care and individualized treatment plans, the center serves as a crucial resource for anyone looking for comprehensive rehabilitation services.

Mark Twain Behavioral Health

Mark Twain Behavioral Health

Macon, MO

Located in Macon, MO, Mark Twain Behavioral Health provides outpatient services for adults dealing with substance use and co-occurring mental health challenges, as well as for children experiencing emotional disturbances. The center is particularly skilled in anger management, substance use disorder counseling, and trauma-related therapy. They adopt a personalized approach, ensuring that treatment plans are tailored to meet the specific needs of each individual. Catering to both adults and children/adolescents, the facility accepts clients of all genders. With an emphasis on delivering high-quality and individualized care, Mark Twain Behavioral Health is dedicated to helping individuals navigate their recovery journeys through evidence-based practices and a team of compassionate professionals.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • Tolerance development requiring escalating doses for the same effect
  • Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • Genetic predisposition to addiction
  • Mental health conditions that drive medication misuse
  • Doctor shopping and obtaining multiple prescriptions
  • Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab