Penn Spine and Rehab Logo
Midwest225 facilities

Drug & Alcohol Rehab Centers in Missouri

Missouri's gateway cities of St. Louis and Kansas City offer extensive treatment networks serving the Midwest region. The state has developed strong prescription monitoring and expanded treatment access.

Serving Kansas City, Saint Louis, Springfield, Columbia and communities throughout Missouri.

Updated: December 19, 2025
Sources:
Verified Information

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call +1 (614) 818-5397
12,000+ Centers
SAMHSA Data

Showing 20 of 225 results

Care STL Health
+9 photos

Care STL Health

Saint Louis, MO 63112
314-367-5820 x3172

Located in Saint Louis, MO, Care STL Health stands out as a leading rehabilitation center, offering a diverse array of treatment options for substance use issues and co-occurring mental health conditions in both adults and children. The facility provides outpatient services such as methadone and buprenorphine treatment, along with cognitive behavioral therapy, ensuring that care is customized for those striving for recovery. They have specialized programs designed for active duty military personnel, adolescents, and adult men, while also extending their services to adults and seniors of any gender. With a strong focus on anger management, brief interventions, and personalized care, the center is dedicated to delivering high-quality support to individuals on their journey toward wellness.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Carestl Health Pope
+9 photos

Carestl Health Pope

Saint Louis, MO 63115
314-385-3990

Situated in Saint Louis, MO, Carestl Health Pope delivers a well-rounded outpatient treatment program for substance use that caters to both adults and children, especially those grappling with serious mental health conditions or emotional issues. The center is known for its specialized services, which include tailored programs for active duty military personnel, adolescents, and adult men, ensuring that each treatment plan is customized to fit the unique needs of every individual. Focusing on key areas like anger management, brief interventions, and cognitive behavioral therapy, this facility is committed to providing top-notch care for adults and seniors across all genders. Whether you're in need of outpatient methadone or buprenorphine treatment, or simply looking for regular outpatient services, Carestl Health Pope stands ready to support individuals on their path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Carestl Health Riverview
+9 photos

Carestl Health Riverview

Saint Louis, MO 63120
314-389-4566

Carestl Health Riverview, located in Saint Louis, MO, offers a wide array of outpatient treatment options for both substance use and co-occurring disorders, catering to adults and children alike. This facility is equipped to serve various groups, including active duty military personnel, adolescents, and adult men, addressing a range of backgrounds and needs. To ensure that care is tailored to each individual, Carestl Health Riverview employs a variety of therapeutic approaches such as anger management, cognitive behavioral therapy, and brief interventions. Additionally, the center provides outpatient services that include treatment with methadone/buprenorphine or naltrexone, alongside regular outpatient options designed for both adult men and women. With a strong commitment to delivering high-quality care, the center supports adults and seniors of all genders, prioritizing evidence-based practices that promote lasting recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Carestlhealth
+9 photos

Carestlhealth

Saint Louis, MO 63113
314-371-3100

Carestlhealth, situated in Saint Louis, MO, stands out as a premier rehabilitation center that specializes in outpatient treatment for adults facing substance use issues and co-occurring serious mental health challenges, as well as addressing significant emotional disturbances in children. The center offers tailored programs specifically designed for active duty military personnel, adolescents, and adult men. Carestlhealth employs a variety of evidence-based strategies, including anger management, brief interventions, and cognitive behavioral therapy. Dedicated to serving adults and seniors of all genders, this facility focuses on delivering high-quality care that is personalized to meet each individual’s unique needs. If you’re looking for comprehensive and effective solutions for addiction treatment, Carestlhealth is here to support you on your path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Central Ozarks Medical Center
+9 photos

Central Ozarks Medical Center

COMC Camdenton Facility

Richland, MO 65556
877-406-2662

Central Ozarks Medical Center, located in Richland, MO, provides outpatient treatment options for adults dealing with substance use and co-occurring mental health challenges, as well as emotional issues in children. Their programs offer various support strategies, such as 12-step facilitation, anger management, and brief interventions. Additionally, they have specialized programs designed for active duty military personnel, adolescents, and adult men. This facility welcomes adults and seniors of all genders, offering a comprehensive array of outpatient services, including methadone and buprenorphine treatment. With a dedication to quality care and personalized approaches, Central Ozarks Medical Center strives to assist individuals on their path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Cape Girardeau Metro Treatment Ctr
+4 photos

Cape Girardeau Metro Treatment Ctr

Metro Treatment of Missouri LP

Cape Girardeau, MO 63703
573-335-4333

Situated in Cape Girardeau, MO, the Cape Girardeau Metro Treatment Center delivers a wide range of outpatient detoxification and substance use treatment services. The center employs various methods, including brief intervention, cognitive behavioral therapy, and motivational interviewing, to support both adults and young adults of all genders. With dedicated programs specifically designed for adult women and those who are pregnant or recently postpartum, this facility aims to provide customized care that addresses the unique needs of each individual. Additionally, the outpatient options for methadone, buprenorphine, or naltrexone treatment ensure that each person receives personalized assistance. By focusing on high-quality care, the Cape Girardeau Metro Treatment Center strives to aid individuals in their recovery journeys.

DetoxificationSubstance use treatment
Clark Community Mental Health Center
+4 photos

Clark Community Mental Health Center

Greenfield, MO 65661
417-235-6610

Clark Community Mental Health Center, situated in Greenfield, MO, specializes in outpatient treatment for adults struggling with substance use and co-occurring mental health challenges, as well as addressing emotional disturbances in children. This facility offers a range of treatment options, including outpatient services for methadone, buprenorphine, or naltrexone. Their treatment philosophy emphasizes personalized care, utilizing techniques such as cognitive behavioral therapy, motivational interviewing, and brief interventions that cater to the unique needs of each individual. By focusing on both adults and children, the center offers tailored programs for all genders, showcasing its commitment to gender-specific care. Clark Community Mental Health Center is dedicated to delivering top-quality support to help individuals navigate their recovery journeys.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Burrell Behavioral Health
+2 photos

Burrell Behavioral Health

Kansas City, MO 64130
816-836-2672

Situated in Kansas City, MO, Burrell Behavioral Health is dedicated to delivering exceptional substance use treatment within a residential environment. This facility features specialized programs designed for adult men, individuals navigating co-occurring mental health and substance use disorders, and those involved in the forensic system. At Burrell, there's an emphasis on 12-step facilitation, catering to a diverse clientele, including adults, seniors, and young adults who are in need of comprehensive care. With both short-term and 24-hour residential programs, the center ensures that male clients receive continuous support. Known for its high-quality care and personalized approaches, Burrell Behavioral Health is truly committed to empowering individuals on their journey to lasting recovery.

Substance use treatment
Center for Addictions
+2 photos

Center for Addictions

Cox Health

Springfield, MO 65802
417-269-2273

Situated in Springfield, MO, the Center for Addictions presents a wide array of treatment options for those facing challenges with substance use disorders. The facility is equipped to provide hospital inpatient detoxification, round-the-clock hospital care, and intensive outpatient programs. Employing techniques such as 12-step facilitation, anger management, and brief intervention, the center serves both adults and children/adolescents grappling with co-occurring mental health issues. Additionally, there are specialized programs designed for trauma survivors and individuals dealing with pain alongside substance use disorders. With an emphasis on personalized care and evidence-based strategies, clients of all genders seeking recovery from addiction receive tailored treatment plans to meet their unique needs.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
BJC Behavioral Health
+1 photos

BJC Behavioral Health

South Site

Saint Louis, MO 63123
314-206-3400

Situated in Saint Louis, MO, BJC Behavioral Health provides a wide array of outpatient treatment options. With a focus on substance use issues and co-occurring disorders, this facility tailors its care for adults facing serious mental health challenges and children dealing with significant emotional disturbances. Their methods incorporate anger management, cognitive behavioral therapy, and brief interventions. Notably, they offer specialized programs for adult women, survivors of sexual abuse, and those who have experienced trauma. BJC Behavioral Health is committed to delivering high-quality care to both adults and children/adolescents, emphasizing personalized treatment plans. Additionally, gender-specific programs are available for both men and women, supporting their recovery and healing journeys.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Brook Wellness Center

Brook Wellness Center

Reeds Spring, MO 65737
417-527-8877

Located in Reeds Spring, MO, Brook Wellness Center offers a wide array of services for those dealing with substance use issues. They provide tailored programs specifically designed for adults facing co-occurring substance use and serious mental health challenges, as well as for children experiencing serious emotional disturbances. The center excels in intensive outpatient treatment, outpatient services, and day treatment options. Additionally, their programs emphasize anger management, brief intervention, and cognitive behavioral therapy, ensuring that adults, adolescents, and children receive top-notch care. They also offer specialized programs for active duty military, adolescents, and adult men, catering to the unique needs of their clients. With a commitment to a holistic approach, the facility welcomes both male and female clients on their path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Clark Community Mental Health Center

Clark Community Mental Health Center

Monett, MO 65708
417-235-6610

Situated in Monett, MO, Clark Community Mental Health Center specializes in outpatient treatment for both substance use disorders and co-occurring conditions, catering to adults and children alike. The center emphasizes personalized care, offering therapy sessions via telemedicine and telehealth options. With a commitment to an individualized approach, Clark Community serves both male and female clients who are on their journey to recovery. Notably, the facility is recognized for its outpatient treatment programs involving methadone, buprenorphine, or naltrexone. If you or someone you care about is facing challenges with addiction and mental health, this center is here to deliver compassionate and tailored care for adults, children, and adolescents.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Comm Mental Health Consultants Inc

Comm Mental Health Consultants Inc

Fast Comprehensive Care

Harrisonville, MO 64701
816-380-4010

Comm Mental Health Consultants Inc, located in Harrisonville, MO, provides a wide range of rehabilitation services aimed at adults and seniors who are facing challenges with substance use and co-occurring mental health conditions. Their offerings include intensive outpatient treatment, outpatient day programs, and partial hospitalization. Using evidence-based methods such as cognitive behavioral therapy and anger management, the center ensures effective care. Additionally, they have specialized programs tailored for adolescents as well as adult men and women, which allows them to address the unique needs of different genders and age groups. Committed to delivering quality care and personalized treatment plans, this facility focuses on supporting clients on their journey to achieve lasting recovery and overall mental wellness.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
BJC Behavioral Health - Placeholder

BJC Behavioral Health

North Site

Florissant, MO 63031
314-747-7491

BJC Behavioral Health, situated in Florissant, MO, provides targeted substance use treatment for both adults and children grappling with serious mental health conditions or emotional difficulties. Their outpatient services include methadone and buprenorphine treatments, as well as cognitive behavioral therapy. This center features distinct programs designed for adult women, survivors of sexual abuse, and individuals affected by trauma. Emphasizing anger management and brief interventions, BJC ensures personalized care for all clients, regardless of gender. Their commitment to offering high-quality, individualized treatment helps support those on their journey to overcoming addiction and addressing mental health issues.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Bootheel Counseling Services - Placeholder

Bootheel Counseling Services

Sikeston, MO 63801
573-471-0800

Bootheel Counseling Services, located in Sikeston, MO, provides outpatient treatment for substance use disorders, along with specialized support for adults facing serious mental health issues or children dealing with emotional disturbances. The center utilizes a variety of treatment methods, including anger management, brief interventions, and cognitive behavioral therapy, to deliver consistent outpatient care. Additionally, Bootheel Counseling Services has dedicated programs for active duty military personnel, adolescents, and adult men, serving a diverse group of adults and seniors across all genders. The facility is committed to offering quality care and personalized assistance to individuals seeking help with both addiction and mental health challenges.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Bootheel Counseling Services - Placeholder

Bootheel Counseling Services

Sikeston, MO 63801
573-621-4129

Located in Sikeston, MO, Bootheel Counseling Services provides outpatient treatment for substance use issues and co-occurring disorders. They cater to adults grappling with significant mental health conditions and also offer support for children facing emotional challenges. This facility excels in counseling for substance use disorders, specifically designed for active duty military personnel, adolescents, and adult men. Although it primarily focuses on adult clients, Bootheel Counseling Services is open to both men and women who are looking for thorough and effective treatment options. What sets this center apart is its wide range of programs and a personalized approach aimed at helping individuals successfully navigate their journeys to recovery from addiction and mental health obstacles.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Carole - Placeholder

Carole

Cadue Blackwood

Kansas City, MO 64111
816-421-7608 x227

Situated in Kansas City, MO, "Carole" provides a wide range of substance use treatment options for adults dealing with mental health issues as well as for children facing serious emotional disturbances. The center offers intensive outpatient, outpatient, and regular outpatient programs that incorporate evidence-based methods, including 12-step facilitation, anger management, and brief interventions. What sets "Carole" apart is its targeted programs designed for adolescents, adult men, and adult women. With a commitment to serving adults and seniors of all genders, this facility prioritizes delivering care that is customized to meet individual needs. If you're in search of effective addiction treatment within a nurturing environment, you’ll find that "Carole" is dedicated to helping you on your path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Centrec Care - Placeholder

Centrec Care

Saint Louis, MO 63141
314-205-8068 x0

Located in Saint Louis, MO, Centrec Care provides a wide range of addiction treatment services tailored for both adults and young adults. The facility specializes in detoxification and offers treatment for substance use, along with focused support for individuals facing co-occurring substance use disorders and serious mental health challenges in adults, as well as emotional issues in children. With a variety of options such as intensive outpatient, outpatient, and day treatment programs, individuals can benefit from services that include 12-step facilitation, anger management, and brief intervention methods. Centrec Care is designed to serve adult men, women, and active duty military personnel, ensuring that each individual receives customized care that promotes recovery. This makes Centrec Care an excellent choice for anyone in search of effective and compassionate support for their addiction treatment journey.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Clark Community Mental Health Center - Placeholder

Clark Community Mental Health Center

Cassville, MO 65625
417-235-6610

Situated in Cassville, MO, Clark Community Mental Health Center provides a wide range of outpatient services for those dealing with substance use challenges. The center focuses on addressing both co-occurring substance use disorders and serious mental health issues in adults, as well as emotional disturbances in children. They offer personalized care through various methods, including brief interventions, cognitive behavioral therapy, and motivational interviewing. With programs specifically designed for both adults and children/adolescents, the center adopts a gender-specific approach for clients of all genders. Whether individuals are looking for regular outpatient treatment or more specialized options like methadone, buprenorphine, or naltrexone treatments, they can anticipate receiving exceptional and tailored support as they work on their recovery journey.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Comm Mental Health Consultants Inc - Placeholder

Comm Mental Health Consultants Inc

FastComprehensive Care

Nevada, MO 64772
417-667-8352

Comm Mental Health Consultants Inc, located in Nevada, MO, provides a wide array of evidence-based treatment options for those struggling with substance use disorders and concurrent mental health issues. Their services include intensive outpatient treatment, outpatient day therapy, and partial hospitalization, all designed to suit the individual needs of both adults and children. The center emphasizes methods like cognitive behavioral therapy and anger management, and also features specialized programs for active duty military members, teenagers, and adult men. Catering to people of all genders, the facility is dedicated to delivering quality care to assist individuals on their path to recovery.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Addiction Treatment in Missouri

Missouri's gateway cities of St. Louis and Kansas City offer extensive treatment networks serving the Midwest region. The state has developed strong prescription monitoring and expanded treatment access.

Treatment Landscape in Missouri

Missouri treatment centers serve as regional hubs for the Midwest. The state offers diverse options from major medical centers in the cities to rural community programs. Veterans services are particularly strong.

Why Choose Treatment in Missouri?
  • Central location accessible from many states
  • Strong veterans treatment programs
  • Urban and rural treatment options
  • Growing medication-assisted treatment access
Gateway city treatment hub
Prescription drug monitoring
Veterans programs

Major Treatment Areas in Missouri

Kansas CitySaint LouisSpringfieldColumbia
Insurance & Payment in Missouri

MO HealthNet (Medicaid) covers behavioral health services. Medicaid expansion has increased access.

Types of Treatment Available

  • Medical Detox: Safe, supervised withdrawal with 24/7 medical support
  • Residential Treatment: Live-in programs with structured daily therapy
  • Partial Hospitalization (PHP): Intensive day treatment programs
  • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • Standard Outpatient: Weekly therapy and support groups
  • Sober Living: Transitional housing for ongoing recovery support

Expert Tips for Missouri

Expert Tip

St. Louis and Kansas City serve as regional treatment hubs with diverse program options.

Expert Tip

Veterans programs are particularly strong in Missouri — ask about specialized services.

Expert Tip

Central location makes Missouri accessible for out-of-state patients seeking treatment.

Missouri Treatment Resources

Official state resources and organizations providing addiction treatment support in Missouri.

Missouri Department of Mental Health

State resource for addiction treatment in Missouri

MO HealthNet

State resource for addiction treatment in Missouri

National Resources

Federal resources and hotlines available 24/7 for addiction support.

Free, confidential, 24/7, 365-day-a-year treatment referral and information service

Find treatment facilities in your area

Provides 24/7 free and confidential support for people in distress

Research and information on drug use and addiction

Frequently Asked Questions

Important Notice

This website provides general information about addiction treatment facilities. It is not a substitute for professional medical advice, diagnosis, or treatment. If you are experiencing a mental health crisis, please call 988 (Suicide & Crisis Lifeline) or 911 for immediate assistance. For substance abuse help, call SAMHSA at 1-800-662-4357.

Data sourced from SAMHSA Treatment Locator, state licensing databases, and facility submissions.