Penn Spine and Rehab Logo

Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(223) 235-7839
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 8160 prescription drug abuse rehab centers

Montefiore Medical Center
+9 photos

Montefiore Medical Center

Bronx, NY

Situated in the Bronx, NY, Montefiore Medical Center specializes in outpatient treatment for both substance use issues and co-occurring mental health disorders in both adults and children. The center employs a variety of evidence-based methods, including cognitive behavioral therapy and motivational incentives, to enhance the therapeutic experience. By prioritizing individualized care, Montefiore Medical Center is focused on customizing treatment to address the distinctive needs of each client. Catering to adults and young adults of all genders, the facility provides outpatient services that include methadone, buprenorphine, and naltrexone treatment. For anyone in search of effective addiction support in a nurturing setting, Montefiore Medical Center is committed to guiding individuals on their path to long-lasting recovery.

Urgent Care Gretna
+9 photos

Urgent Care Gretna

Gretna, LA

Situated in Gretna, LA, Urgent Care Gretna provides outpatient detoxification and treatment for substance use specifically designed for both adults and young adults. This center delivers consistent outpatient care through substance use disorder counseling, along with telemedicine and telehealth services. With targeted programs aimed at active duty military personnel, men, and women, the facility supports a wide array of individuals. No matter your gender, Urgent Care Gretna is committed to offering personalized care that meets each person's unique needs. If you're looking for a nurturing environment to tackle addiction, this facility is focused on guiding you toward a sustainable recovery.

Luxe Recovery
+9 photos

Luxe Recovery

Los Angeles, CA

Situated in Los Angeles, CA, Luxe Recovery is dedicated to providing thorough addiction treatment for both adults and young adults. This facility features long-term residential care, offering detoxification services alongside round-the-clock support. Luxe Recovery specializes in addressing co-occurring substance use and significant mental health challenges, particularly for those who have experienced trauma or sexual abuse. With tailored programs designed for both male and female clients, Luxe Recovery employs evidence-based methods, such as 12-step facilitation and anger management, to ensure high-quality care. Clients seeking either brief interventions or more intensive residential programs can look forward to receiving personalized treatment at Luxe Recovery.

Virginia Hospital Center
+9 photos

Virginia Hospital Center

Arlington, VA

At Virginia Hospital Center located in Arlington, VA, those facing challenges with substance use disorders can access a broad spectrum of care customized to fit their specific needs. This facility provides a range of services, including detoxification, treatment for substance use, and specialized programs that address both co-occurring substance use and serious mental health issues in adults, as well as emotional challenges in children. With various treatment options available, such as intensive outpatient programs, outpatient services, and outpatient detoxification, the center employs diverse methods like 12-step facilitation, anger management, and cognitive behavioral therapy. The programs are designed with an individualized approach to support adults and young adults of all genders, ensuring that everyone who seeks help receives top-notch care on their path to recovery.

Medical City Green Oaks Hospital
+9 photos

Medical City Green Oaks Hospital

Dallas, TX

Situated in Dallas, TX, Medical City Green Oaks Hospital is dedicated to offering a wide range of rehabilitation services for individuals facing challenges with substance use alongside co-occurring mental health issues. The facility specializes in inpatient detoxification and treatment programs designed for both adults and children/adolescents. Their approach emphasizes the use of 12-step facilitation, brief intervention, and motivational interviewing techniques. For young patients and those dealing with dual diagnoses, Medical City Green Oaks Hospital provides tailored programs that ensure each individual, regardless of gender, receives personalized care. What truly sets this hospital apart is its unwavering commitment to providing high-quality, evidence-based treatment. This dedication solidifies its reputation as a leading choice for anyone seeking effective and compassionate support on their journey to addiction recovery.

VA Puget Sound Healthcare System
+9 photos

VA Puget Sound Healthcare System

Seattle, WA

Situated in Seattle, WA, the VA Puget Sound Healthcare System provides a full range of addiction treatment services aimed at both adults and young adults. This facility specializes in various aspects of care, including detoxification, substance use treatment, and addressing co-occurring mental health challenges. Among the treatment options are hospital inpatient detoxification, intensive outpatient programs, and 24-hour inpatient care. The center emphasizes evidence-based strategies like cognitive behavioral therapy and contingency management, serving both men and women, as well as clients who have faced sexual abuse. With a strong focus on personalized care and high-quality treatment, this center stands out as an excellent option for individuals in search of effective rehabilitation services.

Positive Recovery LLC
+9 photos

Positive Recovery LLC

Houston, TX

Positive Recovery LLC, situated in Houston, TX, provides a wide range of substance use treatment options tailored for both adults and young adults. The facility offers several levels of care, including intensive outpatient treatment, outpatient services, and outpatient day treatment/partial hospitalization. Emphasizing a blend of 12-step facilitation, brief interventions, and cognitive behavioral therapy, this center is well-equipped to support adult men and women, including those who have faced trauma. To ensure that every client receives specialized care, Positive Recovery LLC has designed programs that cater to different genders and age groups. With a strong commitment to high-quality, evidence-based treatment, this center stands out as an excellent choice for anyone searching for compassionate and effective addiction recovery solutions.

Recovery Pathways LLC
+9 photos

Recovery Pathways LLC

Essexville, MI

Recovery Pathways LLC, situated in Essexville, MI, is dedicated to delivering comprehensive outpatient treatment for adults dealing with substance use issues alongside significant mental health challenges. The facility focuses on outpatient options such as methadone, buprenorphine, and naltrexone treatments, employing various methods including 12-step facilitation, anger management, and brief intervention techniques. They also offer specialized programs for active duty military members, adolescents, and adult men, ensuring a wide-reaching approach to care. By providing services to adults as well as children and adolescents of all genders, Recovery Pathways LLC emphasizes high-quality treatment aimed at supporting individuals throughout their recovery journeys.

Gateway Rehab
+9 photos

Gateway Rehab

Beaver Falls, PA

Located in Beaver Falls, PA, Gateway Rehab specializes in long-term residential treatment for adult men dealing with substance use. The center offers a range of options, including transitional housing and sober living facilities like halfway houses. Catering to both seniors and older adults, Gateway Rehab also extends its support to young adults in need of a nurturing recovery environment. The facility employs a variety of methods, such as 12-step facilitation, anger management, and brief interventions to provide tailored care for each individual. Known for its high-quality services, Gateway Rehab is dedicated to delivering a holistic treatment approach that fosters long-term sobriety and overall health.

Saint Cloud VAMC
+9 photos

Saint Cloud VAMC

Saint Cloud, MN

Saint Cloud VAMC, located in Saint Cloud, MN, provides a wide range of addiction treatment services for adults and young adults dealing with substance use disorders and accompanying mental health issues. The facility offers hospital inpatient detoxification, treatment, and around-the-clock care, featuring specialized programs tailored for veterans. With a variety of therapeutic approaches including 12-step facilitation, anger management, and brief intervention, the center serves both male and female clients. Committed to delivering quality care and personalized treatment plans, Saint Cloud VAMC is focused on helping clients navigate their journey to recovery.

MCCA Trinity Glen Womens Program
+9 photos

MCCA Trinity Glen Womens Program

Kent, CT

Nestled in Kent, CT, the MCCA Trinity Glen Women's Program delivers top-notch long-term residential treatment for adult women facing substance use issues alongside mental health challenges. This facility places a special emphasis on supporting pregnant and postpartum women, ensuring a nurturing and secure atmosphere that meets their specific needs. The comprehensive care offered here includes methods such as 12-step facilitation, anger management, and cognitive behavioral therapy, catering to adults, seniors, and young adults alike. Additionally, the program is equipped to tackle serious emotional disturbances experienced by children. At MCCA Trinity Glen Women's Program, the commitment to providing high-quality, gender-focused care shines through, empowering women as they navigate their recovery journeys.

Lowell Comprehensive Treatment Center
+9 photos

Lowell Comprehensive Treatment Center

Lowell, MA

Situated in Lowell, MA, the Lowell Comprehensive Treatment Center specializes in outpatient substance use treatment tailored for both adults and young adults. This facility offers treatments such as methadone, buprenorphine, or naltrexone, employing methods like 12-step facilitation, anger management, and brief interventions. They have distinctive programs designed specifically for adult men, women, and clients who have faced intimate partner or domestic violence. Committed to providing individualized care, this center welcomes both male and female clients with understanding and professionalism. If you’re looking for effective and compassionate support for addiction, the Lowell Comprehensive Treatment Center is a reliable option.

Vegas Stronger
+9 photos

Vegas Stronger

Las Vegas, NV

Located in Las Vegas, NV, Vegas Stronger specializes in providing thorough substance use treatment for both adults and young adults who are dealing with serious mental health challenges at the same time. The center offers a range of treatment options, including intensive outpatient, outpatient, and regular outpatient programs. Emphasizing 12-step facilitation, anger management, and brief intervention, Vegas Stronger customizes its programs to address the unique needs of each individual. One of the center’s key features is its specialized approach, which includes gender-specific care tailored for both males and females. If you're in search of personalized, evidence-based treatment within a nurturing environment, Vegas Stronger is committed to supporting you on your path to lasting recovery.

Rosary Hall
+9 photos

Rosary Hall

Cleveland, OH

Nestled in Cleveland, OH, Rosary Hall stands out as a well-respected rehabilitation center dedicated to helping those battling substance use issues. The center provides a range of options, including intensive outpatient treatment, outpatient programs, and outpatient services featuring methadone, buprenorphine, or naltrexone. Employing a variety of effective approaches such as 12-step facilitation, brief interventions, and cognitive-behavioral therapy, Rosary Hall serves adult men and women, as well as young adults. With an emphasis on personalized care, the facility offers specialized programs designed to address the unique needs of both genders. If you or someone you care about is looking for reliable addiction treatment, Rosary Hall presents a comprehensive selection of services tailored to accommodate a variety of requirements.

Above and Beyond Family Recovery Ctr
+9 photos

Above and Beyond Family Recovery Ctr

Chicago, IL

Situated in Chicago, IL, the Above and Beyond Family Recovery Center is dedicated to providing thorough substance use treatment for both adults and young adults. This center takes a particular interest in addressing co-occurring substance use and severe mental health issues, as well as emotional challenges in children. They offer a spectrum of treatment options, including intensive outpatient, outpatient, and standard outpatient programs, allowing individuals to receive customized care that fits their personal needs. Moreover, the facility boasts specialized programs tailored for active duty military personnel, as well as initiatives aimed at adult men and women, fostering a welcoming and supportive atmosphere for everyone. By implementing techniques like 12-step facilitation, anger management, and brief interventions, the center emphasizes high-quality, personalized care designed to support enduring recovery.

Field of Hope Community Campus Inc
+9 photos

Field of Hope Community Campus Inc

Vinton, OH

Field of Hope Community Campus Inc, situated in Vinton, OH, offers a variety of services aimed at addressing substance use issues, including transitional housing and sober living arrangements. The facility features programs such as intensive outpatient, outpatient, and day treatment, employing methods like 12-step facilitation, anger management, and brief intervention. With tailored programs for adolescents, adult men, and women, the center serves a broad spectrum of individuals. Committed to providing care for both adults and children/adolescents, Field of Hope Community Campus Inc focuses on delivering personalized support to everyone. The center prides itself on quality and individualized treatment, dedicated to aiding individuals as they navigate their recovery journey.

Olive Branch Recovery
+9 photos

Olive Branch Recovery

Springdale, AR

Olive Branch Recovery, situated in Springdale, AR, provides outpatient detoxification and substance use treatment tailored for both adults and young adults. The center prides itself on offering specialized care that emphasizes 12-step facilitation, relapse prevention, and counseling for substance use disorders. Focusing on a personalized approach, Olive Branch Recovery serves both male and female clients who are in search of high-quality addiction treatment. Whether you need detoxification or outpatient services like methadone, buprenorphine, or naltrexone treatment, this facility is dedicated to ensuring that each individual embarks on a comprehensive and tailored recovery journey.

Easterseals Blake Foundation
+9 photos

Easterseals Blake Foundation

Tucson, AZ

Easterseals Blake Foundation, situated in Tucson, AZ, provides a full range of outpatient services aimed at addressing substance use issues as well as co-occurring mental health disorders in adults, along with emotional disturbances in children. The center features tailored programs not only for adolescents but also for adult men and women, making it accessible to a diverse demographic, including seniors. Their treatment methods encompass anger management, cognitive behavioral therapy, and motivational incentives. Committed to delivering high-quality care, the facility offers outpatient options for methadone/buprenorphine and naltrexone treatment, alongside regular outpatient services. This ensures that clients—both male and female—receive personalized support on their journey toward recovery and well-being.

Elmhurst Hospital Center
+9 photos

Elmhurst Hospital Center

Elmhurst, NY

Elmhurst Hospital Center, situated in Elmhurst, NY, provides extensive rehabilitation services aimed at adults and young adults who are facing challenges with substance use disorders and concurrent mental health issues. The center features inpatient detoxification and treatment programs, along with specialized options for adults, which include support for those who have experienced intimate partner violence. To aid recovery, the facility utilizes personalized approaches like 12-step facilitation and motivational incentives. Recognizing the importance of gender-specific care, the center offers tailored treatment plans for both men and women, ensuring that each client receives the individual attention they need. With a strong dedication to quality care and evidence-based methods, Elmhurst Hospital Center stands out as a reliable option for those seeking effective and compassionate support for addiction treatment.

Red Rock Recovery Center
+9 photos

Red Rock Recovery Center

Morrison, CO

Nestled in Morrison, CO, Red Rock Recovery Center is dedicated to offering a wide array of rehabilitation services designed for both adults and young adults. The center focuses on detoxification, treatment for substance use disorders, and support for individuals facing co-occurring substance use and serious mental health challenges. With options like residential detoxification and short-term residential programs, Red Rock Recovery Center emphasizes personalized care. They utilize various approaches, including 12-step facilitation, brief intervention, and cognitive behavioral therapy. The facility serves adult men and women, along with clients who have faced trauma. Thanks to its commitment to high-quality care and specialized programs, Red Rock Recovery Center stands out as an excellent choice for those in search of effective and compassionate addiction treatment.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • •Tolerance development requiring escalating doses for the same effect
  • •Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • •Genetic predisposition to addiction
  • •Mental health conditions that drive medication misuse
  • •Doctor shopping and obtaining multiple prescriptions
  • •Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab