Penn Spine and Rehab Logo

Prescription Drug Abuse Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Prescription drug abuse treatment provides medically supervised care for individuals who have developed dependency on medications such as benzodiazepines, sleep aids, or prescription stimulants. Programs include gradual tapering protocols, therapy to address underlying issues, and education on safe medication practices.

Found 8,160 rehab centers specializing in prescription drug abuse across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(223) 235-7839
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 8160 prescription drug abuse rehab centers

S2L Recovery
+9 photos

S2L Recovery

Woodbury, TN

S2L Recovery, located in Woodbury, TN, provides a wide range of addiction treatment services tailored to meet individual needs. The facility offers detoxification, substance use treatment, and specialized care for adults facing co-occurring substance use and serious mental health issues, as well as for children dealing with significant emotional disturbances. Patients can choose from various options, including intensive outpatient programs, long-term residential care, and outpatient services, allowing for flexibility in their recovery journey. The center employs a multifaceted approach that features anger management, brief interventions, and cognitive behavioral therapy. Additionally, S2L Recovery has special programs designed for active duty military members, adult men, and those who have experienced intimate partner violence or domestic violence. The center is committed to serving adults, seniors, and young adults within a male-focused environment, ensuring that all individuals receive the quality care and support they need on their path to recovery.

Regional Health Systems
+9 photos

Regional Health Systems

East Chicago, IN

Regional Health Systems, situated in East Chicago, IN, provides a broad spectrum of treatment options for adults and seniors dealing with substance use disorders alongside co-occurring mental health issues. The center offers intensive outpatient treatment, outpatient detox, and a variety of outpatient services customized to meet the unique needs of each individual. Specialized programs are available for pregnant and postpartum women, as well as for clients with dual diagnoses. The facility utilizes evidence-based practices, including 12-step facilitation and anger management, to support its patients. At Regional Health Systems, both men and women receive quality care, with a strong emphasis on creating personalized treatment plans that promote enduring recovery.

Navajo Regional
+9 photos

Navajo Regional

Shiprock, NM

Situated in Shiprock, NM, Navajo Regional offers a wide array of treatment options for both substance use issues and co-occurring mental health disorders. The facility caters to adults as well as children and adolescents, providing intensive outpatient, long-term residential, and outpatient services to meet diverse needs. They have tailored programs specifically for adolescents and for adult men and women. Utilizing evidence-based methods, including 12-step facilitation, anger management, and brief interventions, Navajo Regional is committed to delivering top-notch care. With a focus on creating personalized treatment plans, this center aims to support both men and women on their journey toward lasting recovery and overall well-being.

CuraSouth
+9 photos

CuraSouth

Largo, FL

CuraSouth, situated in Largo, FL, provides exceptional detoxification and substance use treatment services. This facility emphasizes residential care and offers round-the-clock support. It features tailored programs for adult men and women, including those who have faced intimate partner violence. Employing evidence-based methods such as 12-step facilitation, anger management, and brief intervention, CuraSouth serves adults and young adults across all gender identities. What truly sets CuraSouth apart is its holistic and compassionate approach to care, positioning it as a prime option for anyone in search of high-quality rehabilitation services within a nurturing atmosphere.

Saint Marks Place Institute for MH Inc
+9 photos

Saint Marks Place Institute for MH Inc

New York, NY

Saint Marks Place Institute for Mental Health Inc, located in New York, NY, provides a wide range of outpatient services tailored to detoxification, substance use treatment, and co-occurring disorders for both adults and children. The facility employs various therapeutic methods, including anger management, cognitive behavioral therapy, and motivational interviewing, to meet the unique needs of its clients. Saint Marks Place Institute is particularly welcoming to LGBTQ individuals, as well as those struggling with pain and substance use disorders, and clients facing concurrent mental health challenges. With specific programs designed for different age groups and genders, the institute focuses on delivering personalized care that addresses a variety of needs. Patients have the option to access outpatient detoxification, as well as methadone and buprenorphine treatments, all aimed at providing high-quality support for anyone on their journey toward addiction recovery and improved mental health.

BrightView Health
+9 photos

BrightView Health

Paris, KY

BrightView Health, situated in Paris, KY, provides a range of addiction treatment services designed for both adults and young adults. The center specializes in detoxification and offers a variety of substance use treatment options, including intensive outpatient, outpatient, and day treatment programs. With a focus on individual needs, the facility employs various methods, such as anger management, brief intervention, and cognitive behavioral therapy. This personalized approach ensures that all clients, regardless of gender, receive the support they need for effective rehabilitation. If you're in search of a nurturing environment that emphasizes quality care and tailored treatment plans, BrightView Health is committed to assisting individuals on their path to recovery.

North Oklahoma County MH Center Inc
+9 photos

North Oklahoma County MH Center Inc

Oklahoma City, OK

North Oklahoma County MH Center Inc, located in Oklahoma City, OK, provides outpatient treatment for substance use along with specialized support for individuals dealing with co-occurring substance use and serious mental health disorders in adults, as well as severe emotional disturbances in children. The center employs various therapeutic methods, including anger management, cognitive behavioral therapy, and brief interventions. This facility serves a wide range of clients, such as those involved with the criminal justice system, veterans, and young adults. Catering to adults and seniors of all genders, North Oklahoma County MH Center offers regular outpatient services, in addition to outpatient treatments featuring methadone, buprenorphine, or naltrexone. With a commitment to high-quality care and customized programs, this center stands out as an essential resource for anyone seeking comprehensive rehabilitation services.

HOPE Community Services Inc
+9 photos

HOPE Community Services Inc

Oklahoma City, OK

HOPE Community Services Inc, located in Oklahoma City, OK, provides extensive substance use treatment for adults who are facing co-occurring serious mental health issues, as well as emotional challenges in children. The center offers a variety of outpatient services, including intensive outpatient treatment and specialized programs designed for active duty military personnel, adolescents, and adult men. Utilizing methods such as 12-step facilitation, anger management, and brief intervention, this facility is committed to serving adults and seniors of all genders. With a focus on personalized care, HOPE Community Services Inc stands out as an essential resource for those seeking effective addiction treatment in a nurturing environment.

Kensington Hospital
+9 photos

Kensington Hospital

Philadelphia, PA

Kensington Hospital, situated in Philadelphia, PA, provides a wide range of addiction treatment services aimed at both adults and young adults. The center places a strong emphasis on detoxification and substance use treatment, offering hospital inpatient programs that are customized to meet each person's unique needs. By implementing methods such as 12-step facilitation, cognitive behavioral therapy, and brief interventions, Kensington Hospital ensures a thorough and holistic recovery experience. One of the standout features of this facility is its dedication to personalized care, using a tailored approach for every individual. The center serves both male and female clients, putting a premium on high-quality care and support for anyone looking to overcome addiction and reclaim their life.

Casa Recovery
+9 photos

Casa Recovery

San Juan Capistrano, CA

Casa Recovery, situated in San Juan Capistrano, CA, provides a wide range of rehabilitation services tailored for adults and young adults facing challenges with substance use disorders alongside co-occurring mental health issues. The facility offers several programs, including intensive outpatient treatment, outpatient day treatment, and partial hospitalization. At Casa Recovery, you'll find a strong emphasis on 12-step facilitation, anger management, and brief intervention methods. They also offer specialized programs designed for individuals who have endured sexual abuse or trauma, as well as those coping with both mental health and substance use disorders. With a commitment to personalized care, Casa Recovery welcomes both male and female clients, fostering a nurturing environment for anyone on their journey to recovery.

Recovery Centers of America
+9 photos

Recovery Centers of America

Danvers, MA

Recovery Centers of America, located in Danvers, MA, provides a wide range of substance use treatment options along with specialized care for those dealing with co-occurring mental health disorders. The facility offers intensive outpatient, outpatient, and partial hospitalization programs that utilize evidence-based methods such as 12-step facilitation, anger management, and brief interventions. With programs specifically designed for active duty military personnel and adult men and women, the center is adept at meeting the needs of various demographics. Serving adults and young adults of all genders, this center focuses on delivering high-quality care through personalized treatment plans aimed at fostering lasting recovery.

Zinnia Exeter
+9 photos

Zinnia Exeter

Exeter, RI

Situated in Exeter, RI, Zinnia Exeter stands out as a leading rehabilitation center that offers an array of specialized services for those looking to recover from substance use disorders. The facility features hospital inpatient detoxification, round-the-clock hospital inpatient care, and long-term residential treatment options. With a strong emphasis on 12-step facilitation, anger management, and brief intervention strategies, Zinnia Exeter serves adult men and women, including clients who have faced intimate partner violence or domestic violence. Catering to adults and young adults of all genders, this center is committed to delivering top-notch, comprehensive care to assist individuals on their path to sobriety.

Eleanor Health
+9 photos

Eleanor Health

Durham, NC

Situated in Durham, NC, Eleanor Health delivers a thorough range of outpatient treatment options for adults and young adults struggling with substance use. This facility is particularly skilled in addressing co-occurring substance use disorders in conjunction with significant mental health issues or emotional challenges in children. Their tailored approach features brief interventions, cognitive behavioral therapy, and motivational interviewing techniques. Additionally, Eleanor Health offers outpatient options for methadone, buprenorphine, and naltrexone treatments, along with standard outpatient care. With an emphasis on delivering high-quality, personalized support, this center serves both male and female clients who are seeking evidence-based solutions for their addiction and mental health struggles.

All in Solutions Counseling Center LLC
+9 photos

All in Solutions Counseling Center LLC

Boynton Beach, FL

All in Solutions Counseling Center LLC, located in Boynton Beach, FL, provides a wide range of substance use treatment and transitional housing options. They have specialized programs designed for adult men and women, including those who have faced sexual abuse, ensuring that each person's unique needs are met. The center offers both intensive outpatient and outpatient day treatment formats, incorporating effective strategies like 12-step facilitation, anger management, and brief intervention. Catering to adults and young adults of all genders, All in Solutions fosters a supportive atmosphere conducive to recovery. Committed to delivering high-quality care and customized programs, this facility aims to assist individuals in achieving sustainable sobriety.

Mandala Healing Center
+9 photos

Mandala Healing Center

West Palm Beach, FL

Located in West Palm Beach, FL, Mandala Healing Center provides thorough addiction treatment for both adults and young adults. The facility offers long-term residential programs, residential detoxification, and 24/7 care. By employing evidence-based methods such as cognitive behavioral therapy and anger management, this center customizes its treatment to cater to co-occurring mental health challenges in adults as well as emotional issues in children. With dedicated programs designed for adult men, adult women, and individuals with co-occurring disorders, Mandala Healing Center is focused on delivering personalized care. Its commitment to quality and holistic healing has established it as a reliable option for those on the path to recovery.

Another Way Inc
+9 photos

Another Way Inc

Takoma Park, MD

Another Way Inc, situated in Takoma Park, MD, provides a range of services including outpatient detoxification and treatment for substance use, alongside outpatient methadone, buprenorphine, or naltrexone therapy. The facility employs evidence-based methods such as brief intervention, cognitive behavioral therapy, and motivational interviewing. They cater specifically to adult men and women, as well as individuals dealing with both mental health and substance use issues. Focusing on adults and young adults, Another Way Inc emphasizes personalized care aimed at supporting each individual's recovery journey. With a commitment to quality and compassion, this center strives to help individuals achieve long-term sobriety and overall wellness.

Gateway Foundation
+9 photos

Gateway Foundation

Springfield, IL

Gateway Foundation, located in Springfield, IL, provides a wide range of substance use treatment options for both adults and young people. This facility offers intensive outpatient programs, outpatient services, as well as specialized treatments with methadone, buprenorphine, or naltrexone. They emphasize 12-step facilitation, anger management, and brief intervention strategies, accommodating the needs of both male and female clients. Moreover, they also cater to clients involved with the criminal justice system, ensuring a well-rounded approach to recovery. With a strong focus on high-quality care and customized treatment plans, Gateway Foundation stands out as a reliable option for those in search of effective and personalized addiction treatment services.

Aviary Recovery Center
+9 photos

Aviary Recovery Center

Eolia, MO

Nestled in Eolia, MO, Aviary Recovery Center provides an extensive array of addiction treatment services. The center focuses on detoxification, substance use treatment, and transitional housing options such as halfway houses and sober living homes. With a variety of treatment formats available—including intensive outpatient, long-term residential, and outpatient programs—individuals can discover a personalized pathway to support their recovery journey. This facility is particularly skilled in 12-step facilitation, anger management, and cognitive behavioral therapy. Additionally, Aviary Recovery Center offers specialized programs designed for clients facing co-occurring mental health and substance use disorders, as well as those dealing with pain alongside substance issues. The center is committed to inclusivity, welcoming adults, seniors, and young adults of all genders who are seeking support on their road to rehabilitation.

Substance Abuse Guidance and Education
+9 photos

Substance Abuse Guidance and Education

Waco, TX

Substance Abuse Guidance and Education, situated in Waco, TX, offers specialized outpatient services for individuals struggling with substance use disorders. The facility features regular outpatient programs that include anger management, brief intervention, and cognitive behavioral therapy. With a commitment to personalized care, this center serves both adults and young adults of all genders. Their unique approach ensures that treatment plans are customized to meet the specific needs of each client. Patients can anticipate receiving high-quality, gender-sensitive care designed to foster long-term recovery. If you're in search of a comprehensive substance abuse treatment that prioritizes individualization, this facility may be an excellent fit for you.

Clarksburg Comprehensive Treatment Ctr
+9 photos

Clarksburg Comprehensive Treatment Ctr

Clarksburg, WV

Located in Clarksburg, WV, the Clarksburg Comprehensive Treatment Center offers a variety of services, including outpatient detoxification, substance use treatment, and outpatient care with medications like methadone, buprenorphine, or naltrexone. Their treatment methods embrace anger management, brief interventions, and cognitive behavioral therapy to foster effective recovery. This facility serves a diverse clientele, accommodating adult men and women, as well as pregnant and postpartum women, along with adults and young adults of all genders. With a commitment to delivering tailored care for different age groups and genders, Clarksburg Comprehensive Treatment Center emphasizes personalized treatment plans that cater to each patient's specific needs. Their focus on quality care and evidence-based practices underlines their dedication to guiding individuals on their journey to recovery.

About Prescription Drug Abuse Treatment

Prescription drug abuse often begins with legitimate medical use and can affect anyone. At Penn Spine and Rehab, we help individuals find safe, medically supervised treatment for prescription medication dependency.

Common Prescription Drugs of Abuse

Several categories of prescription medications can lead to dependency:

  • Opioid Pain Medications: OxyContin, Vicodin, Percocet, and others. See our opioid treatment page for specialized information.
  • Benzodiazepines: Xanax, Valium, Klonopin, Ativan—prescribed for anxiety and sleep disorders
  • Sleep Medications: Ambien, Lunesta, and similar sedative-hypnotics
  • Stimulants: Adderall, Ritalin, Concerta—prescribed for ADHD

The Importance of Medical Supervision

Stopping certain prescription medications abruptly can be dangerous. Benzodiazepine and alcohol withdrawal, in particular, can cause life-threatening complications. Medical detoxification provides safe, supervised withdrawal management with gradual tapering protocols.

Treatment Approach

Effective prescription drug treatment typically includes:

  • Medical evaluation and supervised tapering
  • Treatment of underlying conditions (pain, anxiety, ADHD) using non-addictive alternatives
  • Behavioral therapy to address psychological dependency
  • Education on safe medication practices
  • Relapse prevention planning

If you're struggling with prescription medication dependency, you're not alone. Our directory helps you find treatment centers experienced in managing prescription drug withdrawal and recovery.

Causes & Risk Factors for Prescription Drug Abuse

Prescription Drug Abuse develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Overprescribing — high-dose or long-term prescriptions without adequate monitoring
  • •Tolerance development requiring escalating doses for the same effect
  • •Self-medication for untreated pain, anxiety, insomnia, or ADHD
  • •Genetic predisposition to addiction
  • •Mental health conditions that drive medication misuse
  • •Doctor shopping and obtaining multiple prescriptions
  • •Transition from medical use to non-medical use (taking more than prescribed, using for euphoria)

Prescription Drug Abuse Statistics

16.3M

Americans misused prescription psychotherapeutics in 2020

Source: SAMHSA

3.3M

People had prescription drug use disorders in 2020

Source: SAMHSA

14,104

Deaths involving prescription opioids in 2022

Source: CDC

12,499

Deaths involving benzodiazepines in 2021

Source: NIDA

30%

Of benzodiazepine-related deaths also involved opioids

Source: NIDA

6.2M

Americans misused prescription stimulants in 2020

Source: SAMHSA

What to Expect in Prescription Drug Abuse Treatment

1

Medical Assessment (Days 1-2)

Full medication review, determine all substances of dependence. Assess withdrawal risk (especially benzodiazepines). Pain assessment if opioids are involved. Create safe tapering or detox plan.

2

Medical Detox / Taper (1-12 weeks)

Duration depends on substance: opioid detox 5-10 days (with MAT option), benzodiazepine taper 4-16 weeks (gradual dose reduction), stimulant withdrawal 1-2 weeks. 24/7 medical monitoring.

3

Therapeutic Treatment (Weeks 4-12)

CBT to address thought patterns around medication use. Pain management alternatives (for opioids). Anxiety management without benzodiazepines. ADHD management without stimulant misuse.

4

Medication Optimization (Ongoing)

Transition to non-addictive medication alternatives. Establish safe prescribing relationships. Educate on medication safety. Address underlying conditions driving misuse.

5

Aftercare (Ongoing)

Outpatient monitoring, medication management review, peer support. Learn to communicate honestly with healthcare providers. Prescription drug monitoring program awareness.

Frequently Asked Questions About Prescription Drug Abuse Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Prescription Drug Abuse Treatment | Penn Spine and Rehab