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Drug & Alcohol Rehab Centers in Mississippi

Mississippi provides treatment through faith-based and community-centered approaches that honor local values. Gulf Coast facilities offer recovery in peaceful coastal settings.

Serving Jackson, Gulfport, Hattiesburg, Biloxi and communities throughout Mississippi.

Updated: December 19, 2025
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Home of Grace
+9 photos

Home of Grace

Men Addiction Recovery Program

Vancleave, MS 39565
228-826-5283

Situated in Vancleave, MS, Home of Grace specializes in long-term residential treatment for adult men dealing with substance use issues. This facility adopts a comprehensive approach to rehabilitation, catering specifically to the diverse needs of adults, seniors, and young adults. With a primary focus on male clients, Home of Grace fosters a nurturing environment conducive to recovery. The program prioritizes high-quality care and personalized treatment plans, encouraging enduring sobriety. If you or someone close to you is in search of a well-structured and effective rehabilitation program, Home of Grace could be the ideal option for you.

Substance use treatment
Jackson Comprehensive Treatment Center
+9 photos

Jackson Comprehensive Treatment Center

Mississippi Comprehensive Trt Ctr LLC

Jackson, MS 39216
601-718-2468 x201

Nestled in Jackson, MS, the Jackson Comprehensive Treatment Center presents a variety of specialized programs aimed at helping individuals on their journey to recovery from substance use disorders. The center offers detoxification services, intensive outpatient treatment, and outpatient detoxification options. Their treatment methodologies encompass 12-step facilitation, anger management, and brief intervention, ensuring a comprehensive approach to recovery. Additionally, they have programs designed specifically for active duty military members, adult men, and adult women, making their services accessible to a wide range of clients. The Jackson Comprehensive Treatment Center is dedicated to delivering high-quality care to adults and young adults of all genders, supporting those who are dealing with substance use and co-occurring mental health challenges.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Mississippi Drug and Alcohol
+9 photos

Mississippi Drug and Alcohol

Treatment Center

Biloxi, MS 39532
855-334-6120

Located in Biloxi, MS, Mississippi Drug and Alcohol provides a wide range of addiction treatment services for both adults and young adults facing challenges with substance use and related mental health issues. The center offers hospital inpatient detox and treatment, featuring specialized programs designed for active duty military personnel, as well as tailored options for adult men and women. Utilizing methods like 12-step facilitation, cognitive behavioral therapy, and anger management, the facility customizes treatment plans to meet the unique needs of each client. Visitors can anticipate receiving high-quality care and support within a gender-specific environment, all aimed at fostering long-lasting recovery. If you're looking for effective and personalized addiction treatment, this center is committed to guiding you on your journey to sobriety and improved mental health.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
HamiltonDavis Treatment Services
+4 photos

HamiltonDavis Treatment Services

Meridian, MS 39301
601-932-8991

HamiltonDavis Treatment Services, located in Meridian, MS, provides a wide array of rehabilitation programs designed for adults, seniors, and those facing both mental health challenges and substance use disorders. The center offers various options, including intensive outpatient, outpatient, and partial hospitalization programs. By utilizing evidence-based methods such as 12-step facilitation and anger management, they customize care to fit the unique needs of each individual. Additionally, they feature specialized programs for active duty military members and tailored support for adult men and women. At HamiltonDavis Treatment Services, the emphasis is on delivering high-quality care to empower clients on their journey toward lasting recovery.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Hinds Behavioral Health Services
+3 photos

Hinds Behavioral Health Services

Jackson, MS 39209
601-321-2400

Hinds Behavioral Health Services, located in Jackson, MS, provides a variety of specialized treatment programs aimed at addressing substance use and co-occurring mental health challenges for both adults and children. The center offers intensive outpatient and outpatient services, which include treatments with methadone and buprenorphine. With a strong emphasis on anger management, brief interventions, and cognitive behavioral therapy, the facility customizes its approach to meet the unique needs of each individual. Additionally, there are special programs designed specifically for adolescents, adult men, and adult women. Catering to adults and seniors of all genders, Hinds Behavioral Health Services is committed to delivering high-quality care in a nurturing environment that supports recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Jackson VAMC GV Sonny Montgomery
+3 photos

Jackson VAMC GV Sonny Montgomery

Jackson, MS 39216
601-362-4471 x51254

The Jackson VAMC GV Sonny Montgomery facility, situated in Jackson, MS, offers a wide range of detoxification and substance use treatment options tailored for adults and young adults. This center is particularly skilled in addressing co-occurring substance use and serious mental health conditions in adults, as well as serious emotional disturbances in children. Patients benefit from hospital inpatient care, with support available around the clock. The program employs various methods, including 12-step facilitation, anger management, and brief intervention, to meet the needs of both male and female clients. There are also specialized services for active duty military members, adult men, and adult women. By prioritizing high-quality care and personalized treatment plans, this facility stands as a strong support system for individuals on their path to recovery.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Imagine Behavioral Health LLC
+1 photos

Imagine Behavioral Health LLC

Jackson, MS 39216
601-982-5376

Located in Jackson, MS, Imagine Behavioral Health LLC specializes in treating substance use issues and co-occurring disorders in both adults and children. The center offers a range of treatment options, including intensive outpatient, outpatient, and day treatment programs. Their approach incorporates techniques such as 12-step facilitation, anger management, and brief intervention. Imagine Behavioral Health is dedicated to meeting the needs of various groups, including active duty military personnel, adolescents, and adult men. They pride themselves on providing personalized care that adheres to evidence-based practices for adults and seniors of all genders. Whether you’re looking for addiction treatment or support for dual diagnosis, this facility is committed to delivering high-quality care through tailored treatment plans that focus on individual needs.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Harbor Houses of Jackson Inc

Harbor Houses of Jackson Inc

Residential Primary

Byram, MS 39272
601-371-7335

Harbor Houses of Jackson Inc, located in Byram, MS, provides a wide array of addiction treatment services. This facility is designed to support individuals with long-term residential care, residential detoxification, and around-the-clock residential assistance. With a strong emphasis on 12-step facilitation, anger management, and brief intervention strategies, they serve both adult men and women, including those who have faced trauma. The center specializes in programs specifically tailored for adults and young adults, ensuring that both male and female clients receive the attention they need. Harbor Houses of Jackson Inc is committed to delivering high-quality care and support for individuals looking to overcome substance use disorders and move toward a healthier way of life.

DetoxificationSubstance use treatmentTransitional housing, halfway house, or sober home
Innovative Behavioral Services Inc - Placeholder

Innovative Behavioral Services Inc

Ridgeland, MS 39157
601-952-0894 x15

Located in Ridgeland, MS, Innovative Behavioral Services Inc offers a wide array of treatments for substance use. They cater to adults with co-occurring substance use and serious mental health issues, and they also support children facing emotional disturbances. The center provides various options, including intensive outpatient, outpatient, and specialized treatments like methadone/buprenorphine or naltrexone. Their approach emphasizes anger management, brief intervention, and cognitive behavioral therapy, allowing them to customize each program to fit the unique needs of the individual. Innovative Behavioral Services Inc is dedicated to serving people of all genders, from adults to children and adolescents, and is recognized for its commitment to delivering high-quality, personalized care for those in search of recovery from addiction.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Intensive Outpatient

Greenwood, MS 38930
662-455-3222

Life Help Mental Health Center/Region 6, located in Greenwood, MS, provides extensive substance use treatment alongside specialized support for individuals grappling with both substance use and serious mental health challenges. The center offers a variety of treatment options, including intensive outpatient, outpatient, and regular outpatient programs, all grounded in evidence-based practices such as 12-step facilitation, brief intervention, and cognitive behavioral therapy. With a strong emphasis on personalized care, this facility serves adults and young adults of all genders. Their dedication to delivering high-quality care and customized treatment plans has established them as a leading choice for those in search of effective and individualized rehabilitation services.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Coahoma County Office

Clarksdale, MS 38614
662-627-7267

Located in Clarksdale, MS, Life Help Mental Health Center delivers a wide variety of outpatient treatment options aimed at addressing substance use and co-occurring mental health disorders. This facility specializes in care for both adults and young adults, offering programs that emphasize 12-step facilitation, anger management, and brief intervention techniques. Additionally, they feature unique programs specifically designed for those who have faced intimate partner violence or domestic violence, alongside services for criminal justice and forensic clients. With dedicated services for both men and women, Life Help is committed to providing quality support for individuals seeking to navigate their path to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Belzoni Office Humphneys County

Belzoni, MS 39038
662-247-3256

Situated in Belzoni, MS, the Life Help Mental Health Center/Region 6 specializes in outpatient care for adults facing substance use issues and co-occurring serious mental health challenges, as well as emotional disturbances in children. The facility employs various therapeutic methods, including anger management, cognitive behavioral therapy, and motivational interviewing, to provide customized support for adults and seniors of all genders. Notably, the center has dedicated programs catering to active-duty military personnel, adolescents, and adult males, ensuring that a wide range of populations receive the comprehensive assistance they need. With a strong emphasis on evidence-based practices and personalized treatment plans, the center is committed to delivering high-quality care for individuals on their journey to recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Greenville, MS 38701
662-335-5274

Life Help Mental Health Center, located in Greenville, MS, specializes in outpatient treatment for adults dealing with substance use issues alongside co-occurring mental health disorders. They also cater to children's emotional disturbances. Their approach to treatment features various methods, including anger management, cognitive behavioral therapy, and motivational interviewing. This center stands out by offering specialized programs tailored to adolescents, as well as adult men and women. With services designed for both age groups, Life Help Mental Health Center is dedicated to providing quality care to individuals seeking addiction treatment in a nurturing environment. Their commitment to developing gender-specific and age-appropriate programs truly differentiates them in delivering thorough and effective rehabilitation services.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Grenada County Office

Grenada, MS 38901
662-453-6211

Located in Grenada, MS, Life Help Mental Health Center/Region 6 provides outpatient treatment for adults struggling with substance use issues, particularly those with co-occurring serious mental health disorders. Additionally, the center supports children facing serious emotional disturbances. The facility employs a variety of techniques, including cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, to ensure that each client receives personalized care that meets their unique needs. With a commitment to an individual-centered approach, Life Help caters to adults and seniors of all genders. Their focus on high-quality care and evidence-based practices makes Life Help a trusted source for those in search of comprehensive and effective addiction treatment in the Grenada community.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Rolling Fork Office/Issaquena County

Rolling Fork, MS 39159
662-873-6228

Life Help Mental Health Center/Region 6, located in Rolling Fork, MS, provides a wide range of outpatient services aimed at addressing substance use and serious mental health challenges in adults, as well as serious emotional disturbances in children. The center features specialized programs tailored for adolescents, men, and women. It serves adults and seniors of all genders, ensuring that the treatment is customized to fit each person's specific needs. With a strong emphasis on quality care, Life Help Mental Health Center/Region 6 is recognized for its holistic treatment approaches and dedication to supporting clients throughout their recovery journey.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help Mental Health Ctr/Region 6 - Placeholder

Life Help Mental Health Ctr/Region 6

Attala County Office

Kosciusko, MS 39090
662-289-4735

Life Help Mental Health Center/Region 6, located in Kosciusko, MS, provides outpatient services for substance use treatment and offers specialized care for adults grappling with serious mental health issues, as well as for children experiencing significant emotional disturbances. The center employs a range of therapeutic techniques, including 12-step facilitation, anger management, and cognitive behavioral therapy, ensuring that programs are tailored to meet the individual needs of each client. With a strong emphasis on personalized care, Life Help caters to both adults and children/adolescents, regardless of gender. Renowned for its high-quality care and extensive range of services, this center is dedicated to compassionately addressing the unique challenges faced by each client, demonstrating expertise and understanding in their approach.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Life Help/Region 6 CMC - Placeholder

Life Help/Region 6 CMC

Fairland Center

Tutwiler, MS 38963
662-624-2152

Situated in Tutwiler, MS, Life Help/Region 6 CMC provides extensive long-term residential treatment specifically tailored for adult women grappling with substance use disorders alongside serious mental health challenges. This facility emphasizes 12-step facilitation and anger management techniques, offering targeted support for clients who have faced intimate partner violence. In addition, their residential detoxification services and brief intervention programs are designed to assist adults, seniors, and young adults alike. What truly sets Life Help/Region 6 CMC apart is its dedication to delivering high-quality care, making it an excellent option for women looking for a nurturing environment to aid in their recovery journey.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Lifecore Health Group - Placeholder

Lifecore Health Group

Monroe County Office

Amory, MS 38821
662-640-4595

Situated in Amory, MS, Lifecore Health Group provides outpatient services for adults dealing with substance use issues, especially those experiencing co-occurring serious mental health conditions or emotional challenges in children. The center excels in offering anger management, cognitive behavioral therapy, and counseling specifically for substance use disorders. They also have specialized programs designed for individuals involved in the criminal justice system. Lifecore Health Group is dedicated to delivering high-quality care to both men and women in a nurturing environment. With a strong emphasis on evidence-based practices, this facility customizes treatment plans to address the unique needs of both adults and children seeking to overcome substance use and mental health difficulties.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Lifecore Health Group - Placeholder

Lifecore Health Group

Chickasaw County Office

Houston, MS 38851
662-640-4595

Lifecore Health Group, situated in Houston, MS, provides outpatient substance use treatment for both adults and children/adolescents facing serious mental health challenges or emotional disturbances. This facility excels in areas such as anger management, cognitive behavioral therapy, and counseling for substance use disorders. Lifecore Health Group's outpatient services are crafted to meet the specific needs of both male and female clients. What truly distinguishes this facility is its tailored programs for criminal justice and forensic clients, ensuring a comprehensive approach to care. Committed to quality and personalized treatment, Lifecore Health Group aims to support clients on their journey toward lasting recovery and enhanced well-being.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Lifecore Region III MHC - Placeholder

Lifecore Region III MHC

Pontotoc County

Pontotoc, MS 38863
662-509-9300

Lifecore Region III MHC, situated in Pontotoc, MS, provides outpatient treatment for substance use, as well as specialized care for individuals grappling with serious mental health issues that often coexist. This facility employs evidence-based methods, offering regular outpatient services that include anger management, cognitive behavioral therapy, and counseling for substance use disorders. A distinguishing feature of Lifecore Region III MHC is its customized programs tailored specifically for clients involved in the criminal justice system, catering to both adults and children/adolescents. The center is dedicated to delivering quality care and support, focusing on the rehabilitation needs of both male and female clients.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Addiction Treatment in Mississippi

Mississippi provides treatment through faith-based and community-centered approaches that honor local values. Gulf Coast facilities offer recovery in peaceful coastal settings.

Treatment Landscape in Mississippi

Mississippi treatment emphasizes faith, family, and community support alongside clinical care. The state has worked to expand access in rural areas and increase medication-assisted treatment availability.

Why Choose Treatment in Mississippi?
  • Strong faith-based treatment options
  • Gulf Coast healing environments
  • Community-focused recovery approach
  • Lower costs than national average
Faith-based treatment strength
Community-centered care
Gulf Coast facilities

Major Treatment Areas in Mississippi

JacksonGulfportHattiesburgBiloxi
Insurance & Payment in Mississippi

Mississippi Medicaid covers substance abuse treatment. Many facilities offer sliding scale fees.

Types of Treatment Available

  • Medical Detox: Safe, supervised withdrawal with 24/7 medical support
  • Residential Treatment: Live-in programs with structured daily therapy
  • Partial Hospitalization (PHP): Intensive day treatment programs
  • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • Standard Outpatient: Weekly therapy and support groups
  • Sober Living: Transitional housing for ongoing recovery support

Expert Tips for Mississippi

Expert Tip

Faith-based programs are especially strong if spiritual support aligns with your recovery values.

Expert Tip

Gulf Coast facilities offer peaceful coastal healing environments.

Expert Tip

Ask about sliding scale fees — many Mississippi facilities work with patients on affordability.

Mississippi Treatment Resources

Official state resources and organizations providing addiction treatment support in Mississippi.

Mississippi Department of Mental Health

State resource for addiction treatment in Mississippi

National Resources

Federal resources and hotlines available 24/7 for addiction support.

Free, confidential, 24/7, 365-day-a-year treatment referral and information service

Find treatment facilities in your area

Provides 24/7 free and confidential support for people in distress

Research and information on drug use and addiction

Find Treatment by City in Mississippi

Frequently Asked Questions

Important Notice

This website provides general information about addiction treatment facilities. It is not a substitute for professional medical advice, diagnosis, or treatment. If you are experiencing a mental health crisis, please call 988 (Suicide & Crisis Lifeline) or 911 for immediate assistance. For substance abuse help, call SAMHSA at 1-800-662-4357.

Data sourced from SAMHSA Treatment Locator, state licensing databases, and facility submissions.