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Drug & Alcohol Rehab Centers in Mississippi

Mississippi provides treatment through faith-based and community-centered approaches that honor local values. Gulf Coast facilities offer recovery in peaceful coastal settings.

Serving Jackson, Gulfport, Hattiesburg, Biloxi and communities throughout Mississippi.

Updated: December 19, 2025
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Region IV MHS
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Region IV MHS

Chemical Dependency Complex

Corinth, MS 38835
662-286-7199

Region IV MHS, located in Corinth, MS, provides extensive services for addiction treatment and transitional housing. Their expertise lies in addressing both co-occurring substance use disorders and serious mental health issues for adults, along with emotional challenges in children. The center features a variety of programs, including long-term, short-term, and 24-hour residential options. Their offerings include 12-step facilitation, anger management, and brief intervention strategies. This facility supports both adult men and women, accommodating clients who have encountered trauma. Additionally, the center is dedicated to serving both adults and young adults, with specialized care for female and male individuals. Experience personalized programs and quality care at Region IV MHS.

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region IV MHS

Region IV MHS

Desoto County Childrens Services

Hernando, MS 38632
662-449-1808

Region IV MHS, located in Hernando, MS, offers outpatient treatment for substance use as well as co-occurring mental health services for both adults and children. The facility employs evidence-based methods, including anger management, cognitive behavioral therapy, and motivational interviewing, as part of its regular outpatient programs. There are also specialized programs designed for clients who have faced trauma, experienced sexual abuse, or are currently involved in the criminal justice system. Serving clients of all ages, including young adults, the center is committed to delivering high-quality care that meets each individual's specific needs. If you or someone you care about is looking for comprehensive rehabilitation services, this facility is here to support you on the journey to lasting recovery.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Weems Community MH Center

Weems Community MH Center

Leake County Office

Carthage, MS 39051
601-267-3551

The Weems Community MH Center, situated in Carthage, MS, provides outpatient treatment for both adults and children grappling with serious emotional disturbances related to substance use. This facility offers routine outpatient services that incorporate methods like 12-step facilitation, anger management, and brief interventions. The program emphasizes a personalized approach, serving adults and seniors of all genders. With a commitment to delivering high-quality care and customized treatment plans, the center is dedicated to aiding individuals as they navigate their recovery from substance use and concurrent mental health challenges.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region 8 Mental Health Services - Placeholder

Region 8 Mental Health Services

A and D Outpatient

Brandon, MS 39042
601-591-5553

Region 8 Mental Health Services, located in Brandon, MS, provides a diverse array of treatment programs designed to meet different needs. This facility specializes in detoxification, along with substance use treatment, and offers targeted care for adults facing both substance use issues and serious mental health conditions, as well as for children dealing with significant emotional disturbances. The center features various treatment options, including intensive outpatient programs, outpatient services, and day treatment, all grounded in evidence-based methods such as 12-step facilitation, anger management, and brief intervention techniques. Additionally, Region 8 Mental Health Services has unique programs specifically for active duty military personnel, adolescents, and adult men. By serving adults and seniors of all genders, this facility is committed to providing high-quality care that is personalized to each individual's needs.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region 8 Mental Health Services - Placeholder

Region 8 Mental Health Services

A and D Male Residential Trt Center

Mendenhall, MS 39114
601-847-2623

Region 8 Mental Health Services, located in Mendenhall, MS, provides a range of long-term and short-term residential treatment options specifically designed for adult men who are facing substance use issues alongside serious mental health conditions. The center emphasizes trauma-informed care and offers various supportive services, including 12-step facilitation, anger management, and brief interventions. Their programs are tailored to meet the needs of adults, seniors, and young adults, ensuring that each client receives personalized treatment. With a particular focus on those dealing with co-occurring mental health and substance use disorders, Region 8 Mental Health Services is committed to delivering quality care in a nurturing environment. If you or someone you care about is seeking targeted support for substance use or mental health challenges, Region 8 Mental Health Services may be the right choice for you.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region 8 Mental Health Services - Placeholder

Region 8 Mental Health Services

A and D Female Residential Trt Center

Hazlehurst, MS 39083
601-894-6370

Located in Hazlehurst, MS, Region 8 Mental Health Services offers a wide range of addiction treatment options specifically designed for adult women facing challenges related to substance use and significant mental health disorders. The facility provides several types of programs, including long-term residential care, outpatient services, and regular outpatient treatment. Their approach emphasizes 12-step facilitation, anger management, and brief intervention techniques. Additionally, the center features specialized programs aimed at active duty military members, adult women, and individuals who have encountered intimate partner violence. They cater to a diverse clientele that includes adults, seniors, and young adults, with a particular emphasis on supporting female clients. Region 8 Mental Health Services is committed to delivering high-quality care and personalized assistance to individuals who are on their journey to recovery from addiction.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region I Mental Health Center - Placeholder

Region I Mental Health Center

Tunica County Office

Tunica, MS 38676
662-363-3222

Located in Tunica, MS, the Region I Mental Health Center provides a wide array of outpatient services aimed at treating substance use and co-occurring mental health disorders for both adults and children. Their offerings include outpatient day treatment and regular outpatient sessions, utilizing evidence-based practices like 12-step facilitation, brief interventions, and cognitive behavioral therapy. The center also features specialized programs designed specifically for active duty military members, adolescents, and adult men, reflecting its commitment to serving a diverse clientele. By offering care to both men and women in the adult and young adult demographics, Region I Mental Health Center focuses on delivering quality treatment personalized to meet each individual's unique needs.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region III Chem Dependency - Placeholder

Region III Chem Dependency

Tupelo, MS 38804
662-304-3017

Region III Chem Dependency, located in Tupelo, MS, is dedicated to providing thorough addiction treatment services for both adults and young adults facing substance use disorders. This center excels in offering specialized care designed for those grappling with co-occurring mental health conditions, featuring a variety of options such as long-term residential programs, outpatient services, and medication-assisted treatment. By emphasizing methods like 12-step facilitation, anger management, and cognitive behavioral therapy, Region III Chem Dependency adopts a well-rounded approach to recovery. What truly sets this facility apart is its customized programs tailored specifically for clients dealing with both mental health and substance use challenges, accommodating both male and female individuals. Discover compassionate care and support in a welcoming atmosphere at this esteemed rehabilitation center.

DetoxificationSubstance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region IV MH/MR - Placeholder

Region IV MH/MR

Iuka, MS 38852
662-423-3332

Situated in Iuka, MS, Region IV MH/MR stands out as a well-respected rehabilitation center. It provides outpatient treatment for substance use and specialized support for adults grappling with co-occurring substance use disorders and serious mental health challenges, as well as emotional disturbances in children. The program incorporates various techniques, including 12-step facilitation, anger management, and brief interventions. It serves a diverse range of individuals, from adults and seniors to specific groups such as active duty military personnel and adolescents. Committed to delivering high-quality care and tailored treatment, this facility creates a welcoming atmosphere for both men and women seeking effective rehabilitation services in the area.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region IV MHS - Placeholder

Region IV MHS

Corinth, MS 38834
662-287-4424

Region IV MHS, located in Corinth, MS, is dedicated to providing outpatient treatment that focuses on substance use and co-occurring mental health challenges. This facility serves both adults and young adults, offering consistent outpatient care grounded in evidence-based practices such as Cognitive Behavioral Therapy and Motivational Interviewing. Emphasizing the 12-step approach, Region IV MHS effectively supports individuals with dual diagnoses. What sets this center apart is its specialized programs tailored for both men and women, ensuring that each client receives thorough and personalized care. When you choose this facility, you can expect top-quality treatment and support in a warm, inviting atmosphere.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region IV MHS - Placeholder

Region IV MHS

Booneville Extension Office

Corinth, MS 38834
662-286-9883

Region IV MHS, located in Corinth, MS, provides outpatient treatment for adults struggling with substance use and co-occurring mental health issues. Their programs, designed for both adults and seniors, emphasize techniques like 12-step facilitation, anger management, and brief interventions. Additionally, the facility offers specialized programs for adolescents, adult men, and adult women, ensuring that care is tailored to fit a variety of individual needs. With a dedicated focus on quality and evidence-based practices, Region IV MHS is committed to delivering thorough support for those on their recovery journey. Clients of all genders can look forward to a nurturing environment that promotes healing and personal growth.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region XIV Singing River Services - Placeholder

Region XIV Singing River Services

Stevens Center

Pascagoula, MS 39567
228-769-1280 x2050

Located in Pascagoula, MS, Region XIV Singing River Services provides a wide array of addiction treatment options. This facility features residential and short-term residential programs designed for adults and young adults, accommodating both men and women. The center emphasizes approaches such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, personalizing treatment to meet the needs of those facing both substance use and mental health challenges. Additionally, specific programs are tailored for active duty military members, as well as adult men and women. Region XIV Singing River Services is committed to delivering high-quality care in a nurturing environment, supporting individuals as they embark on their recovery journey.

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Region XV Warren Yazoo Chem Dep Ctr - Placeholder

Region XV Warren Yazoo Chem Dep Ctr

Region XV/Mental Health

Vicksburg, MS 39180
601-634-0181 x3301

Region XV Warren Yazoo Chemical Dependency Center, located in Vicksburg, MS, provides a range of services for detoxification and substance use treatment. They offer intensive outpatient programs, long-term residential care, and traditional outpatient services. The center employs various approaches, including 12-step facilitation, brief intervention, and cognitive behavioral therapy, ensuring comprehensive support for adult men and women, particularly those facing co-occurring mental health and substance use challenges. Catering to both adults and young adults of all genders, Region XV Warren Yazoo Chemical Dependency Center delivers personalized care designed to meet each individual's unique needs. With a strong commitment to quality and holistic treatment, the center is devoted to guiding individuals on their journey to recovery.

DetoxificationSubstance use treatment
Serenity Summit CDRC LLC - Placeholder

Serenity Summit CDRC LLC

Summit, MS 39666
601-810-0804

Serenity Summit CDRC LLC, located in Summit, MS, provides outpatient substance use treatment specifically designed for adults and young adults. The center emphasizes tailored programs that incorporate 12-step facilitation, brief interventions, and cognitive behavioral therapy to address each individual’s unique needs. With a specialty in care for adult men, adult women, and clients involved in the criminal justice system, the facility offers gender-specific support. At Serenity Summit CDRC LLC, you’ll find a nurturing atmosphere that prioritizes recovery while utilizing high-quality, evidence-based approaches. If you’re looking for effective addiction treatment in a friendly environment, this center is committed to guiding individuals on their journey to lasting sobriety.

Substance use treatment
Serenity Summit CDRC LLC - Placeholder

Serenity Summit CDRC LLC

Raleigh, MS 39153
601-810-0804

Located in Raleigh, MS, Serenity Summit CDRC LLC provides outpatient treatment for substance use to both adult men and women. The center also features specialized programs designed specifically for clients involved with the criminal justice system. By employing a blend of 12-step facilitation, brief intervention techniques, and cognitive behavioral therapy, Serenity Summit offers well-rounded care that caters to the needs of adults and young adults alike. With a commitment to personalized treatment and support, the facility ensures each individual receives the quality care they need on their path to recovery. Additionally, Serenity Summit embraces a gender-specific approach, carefully addressing the distinct needs of male and female clients. This focus makes the center a valuable resource for those seeking to overcome the challenges of substance use.

Substance use treatment
Weems Community MH Center - Placeholder

Weems Community MH Center

Newton County Office

Decatur, MS 39327
601-728-9461

Located in Decatur, MS, the Weems Community MH Center specializes in outpatient substance use treatment for both adults and children dealing with serious mental health issues or emotional disturbances. The center offers a variety of programs designed to meet individual needs, including 12-step facilitation, anger management, and brief interventions. They provide expert care tailored to adults and seniors of all genders, prioritizing personalized treatment plans to ensure high-quality support throughout the recovery journey. If you're looking for effective and comprehensive addiction treatment in a nurturing environment, the Weems Community MH Center could be the right choice for you.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Weems Community MH Center - Placeholder

Weems Community MH Center

Neshoba County Office

Philadelphia, MS 39350
601-483-4821

Situated in Philadelphia, MS, the Weems Community MH Center provides specialized outpatient care for individuals grappling with substance use and co-occurring disorders, catering to both adults and children. The facility offers regular outpatient services grounded in evidence-based methods, including 12-step facilitation, brief intervention, and cognitive behavioral therapy. What truly distinguishes this program is its personalized approach, which addresses the unique needs of adults and seniors across all genders. Committed to delivering high-quality care and customized interventions, the center is dedicated to supporting clients on their path to recovery. If you’re looking for comprehensive and tailored treatment options, the Weems Community MH Center is ready to assist you.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Weems Community MH Center - Placeholder

Weems Community MH Center

Scott County Office

Forest, MS 39074
601-483-4821

Situated in Forest, MS, the Weems Community MH Center provides targeted outpatient services specifically designed for substance use treatment and co-occurring disorders in both adults and children. The facility employs a variety of methods, including 12-step facilitation, anger management, and brief interventions, ensuring that care is customized to fit each person's unique needs. With a commitment to an individualized approach, the center caters to adults and seniors of all genders. By prioritizing high-quality care and personalized treatment plans, it serves as an essential resource for anyone looking for thorough rehabilitation services in a nurturing setting.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Weems Community MH Center - Placeholder

Weems Community MH Center

Weems LifeCare

Meridian, MS 39307
601-693-1001

The Weems Community MH Center, located in Meridian, MS, provides a wide range of treatment options designed for individuals looking to recover from substance use disorders. This facility features specialized services such as transitional housing, halfway houses, and sober living environments. It supports adults grappling with co-occurring substance use and serious mental health issues, as well as children who are facing significant emotional challenges. Offering various treatment formats, including hospital inpatient care and intensive outpatient programs, this center employs methods such as 12-step facilitation, anger management, and brief interventions to aid in recovery. Moreover, they have tailored programs for adult men, adult women, and clients who have encountered sexual abuse. Welcoming both male and female clients of various age groups, the center is committed to providing personalized care for anyone seeking help on their recovery journey.

Substance use treatmentTransitional housing, halfway house, or sober homeTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Weems Community MH Center - Placeholder

Weems Community MH Center

Smith County Office

Raleigh, MS 39153
601-782-9461

Situated in Raleigh, MS, Weems Community MH Center specializes in outpatient treatment for adults and seniors who are grappling with co-occurring serious mental health challenges and substance use issues. The center employs a variety of strategies, including 12-step facilitation, anger management, and brief intervention, to provide regular outpatient care. With a strong commitment to personalized care, the facility serves both male and female clients who are looking for effective support for their substance use and mental health needs. By prioritizing individualized treatment, Weems Community MH Center distinguishes itself with comprehensive programs tailored to meet the unique requirements of each client.

Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children

Addiction Treatment in Mississippi

Mississippi provides treatment through faith-based and community-centered approaches that honor local values. Gulf Coast facilities offer recovery in peaceful coastal settings.

Treatment Landscape in Mississippi

Mississippi treatment emphasizes faith, family, and community support alongside clinical care. The state has worked to expand access in rural areas and increase medication-assisted treatment availability.

Why Choose Treatment in Mississippi?
  • Strong faith-based treatment options
  • Gulf Coast healing environments
  • Community-focused recovery approach
  • Lower costs than national average
Faith-based treatment strength
Community-centered care
Gulf Coast facilities

Major Treatment Areas in Mississippi

JacksonGulfportHattiesburgBiloxi
Insurance & Payment in Mississippi

Mississippi Medicaid covers substance abuse treatment. Many facilities offer sliding scale fees.

Types of Treatment Available

  • Medical Detox: Safe, supervised withdrawal with 24/7 medical support
  • Residential Treatment: Live-in programs with structured daily therapy
  • Partial Hospitalization (PHP): Intensive day treatment programs
  • Intensive Outpatient (IOP): Flexible scheduling for working professionals
  • Standard Outpatient: Weekly therapy and support groups
  • Sober Living: Transitional housing for ongoing recovery support

Expert Tips for Mississippi

Expert Tip

Faith-based programs are especially strong if spiritual support aligns with your recovery values.

Expert Tip

Gulf Coast facilities offer peaceful coastal healing environments.

Expert Tip

Ask about sliding scale fees — many Mississippi facilities work with patients on affordability.

Mississippi Treatment Resources

Official state resources and organizations providing addiction treatment support in Mississippi.

Mississippi Department of Mental Health

State resource for addiction treatment in Mississippi

National Resources

Federal resources and hotlines available 24/7 for addiction support.

Free, confidential, 24/7, 365-day-a-year treatment referral and information service

Find treatment facilities in your area

Provides 24/7 free and confidential support for people in distress

Research and information on drug use and addiction

Find Treatment by City in Mississippi

Frequently Asked Questions

Important Notice

This website provides general information about addiction treatment facilities. It is not a substitute for professional medical advice, diagnosis, or treatment. If you are experiencing a mental health crisis, please call 988 (Suicide & Crisis Lifeline) or 911 for immediate assistance. For substance abuse help, call SAMHSA at 1-800-662-4357.

Data sourced from SAMHSA Treatment Locator, state licensing databases, and facility submissions.