Penn Spine and Rehab Logo

Depression Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Depression treatment within addiction recovery takes an integrated approach to address both conditions simultaneously. Evidence-based therapies like CBT and DBT, medication management when appropriate, and holistic wellness practices help individuals manage depressive symptoms while building a strong foundation for lasting sobriety.

Found 8,160 rehab centers specializing in depression across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(223) 235-7839
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 8160 depression rehab centers

Family Services of the Piedmont
+7 photos

Family Services of the Piedmont

High Point, NC

Family Services of the Piedmont, located in High Point, NC, specializes in outpatient substance use treatment for adults and young adults facing serious mental health challenges alongside their substance use. The facility employs various techniques, including 12-step facilitation, anger management, and brief intervention, to provide consistent outpatient care. It also features specialized programs designed for specific groups, including active duty military personnel, as well as adult men and women. By offering gender-specific care, the center ensures that each individual receives tailored treatment that meets their unique needs. Clients can look forward to receiving top-notch care and support in a friendly and inviting atmosphere at this facility.

Adapt Integrated Healthcare
+7 photos

Adapt Integrated Healthcare

Roseburg, OR

Adapt Integrated Healthcare, situated in Roseburg, OR, provides long-term and round-the-clock residential treatment programs aimed at adolescents battling addiction. This center stands out for its expertise in 12-step facilitation, brief intervention, and motivational incentives through contingency management. They have tailored programs specifically designed for clients who have gone through trauma, as well as those dealing with both mental health issues and substance use disorders. Committed to delivering high-quality care, Adapt Integrated Healthcare offers specialized services for both male and female clients, ensuring that individuals receive the comprehensive support they need on their road to recovery.

Sierra at Scottsdale
+7 photos

Sierra at Scottsdale

Scottsdale, AZ

Sierra at Scottsdale, located in Scottsdale, AZ, specializes in providing substance use treatment to adults and young adults who are also experiencing serious mental health issues or emotional challenges. The facility offers a range of programs, including intensive outpatient, outpatient, and partial hospitalization options. Emphasizing techniques like anger management, brief intervention, and cognitive behavioral therapy, Sierra at Scottsdale customizes its approach to meet the specific needs of each individual. Additionally, there are unique programs designed for active duty military personnel as well as for adult men and women. This center caters to both genders, delivering high-quality care in a nurturing environment for those in search of comprehensive rehabilitation services.

Beths Place
+7 photos

Beths Place

Moorhead, MN

Beths Place, situated in Moorhead, MN, offers specialized treatment for substance use tailored for both adults and young adults. The center features a range of programs, including intensive outpatient treatment, outpatient programs, and regular outpatient treatment. Emphasizing personalized care, Beths Place employs various techniques such as anger management, brief intervention, and cognitive behavioral therapy. This facility welcomes both male and female clients. With a reputation for customized programs, Beths Place strives to deliver top-notch care and support to those on their journey to recovery from substance use disorders.

Red Willow Counseling and Recovery
+7 photos

Red Willow Counseling and Recovery

Salt Lake City, UT

Red Willow Counseling and Recovery, located in Salt Lake City, UT, offers a complete range of substance use treatments, including intensive outpatient, outpatient, and regular outpatient programs. The facility employs a variety of targeted strategies, such as anger management, brief intervention, and cognitive behavioral therapy, to meet the unique needs of each individual. With specialized programs designed for active duty military members as well as adult men and women, Red Willow caters to a diverse clientele. This center is committed to providing high-quality care and support for both adults and young adults of all genders, creating a professional and compassionate environment for those seeking help with addiction.

New Dawn Recovery Centers
+7 photos

New Dawn Recovery Centers

Citrus Heights, CA

Located in Citrus Heights, CA, New Dawn Recovery Centers provides a variety of specialized programs for individuals looking to overcome substance use issues. Their offerings include everything from hospital inpatient care to intensive outpatient treatment. The facility employs evidence-based methods like anger management, brief interventions, and cognitive behavioral therapy to tackle addiction head-on. Additionally, they have tailored programs specifically designed for adult men, adult women, and those who have faced intimate partner or domestic violence. New Dawn Recovery Centers serves adults and young adults of all genders, creating a supportive and understanding environment for anyone committed to their recovery journey.

Guidance Center
+7 photos

Guidance Center

Southgate, MI

Situated in Southgate, MI, the Guidance Center is dedicated to delivering high-quality rehabilitation services. It specializes in treating substance use issues for both adults and young adults, offering both intensive outpatient and standard outpatient programs. The center employs various therapeutic techniques, including anger management, cognitive behavioral therapy, and the Matrix Model, specifically designed for those facing co-occurring mental health and substance use challenges. With a strong emphasis on personalized care, each program is crafted to address the individual needs of clients. The center is open to all individuals, regardless of gender, who are in search of thorough and effective treatment within a supportive setting.

Behavioral Health Clinic
+7 photos

Behavioral Health Clinic

Baltimore, MD

Situated in Baltimore, MD, the Behavioral Health Clinic provides a wide array of addiction treatment services. This facility specializes in addressing substance use issues along with transitional housing, primarily assisting adults and young adults who are dealing with both substance use and serious mental health challenges. Emphasizing intensive outpatient treatment and outpatient options for methadone and buprenorphine therapy, the clinic also offers programs such as 12-step facilitation, anger management, and brief interventions. They have crafted specialized programs for adult men, adult women, and survivors of sexual abuse to ensure that care is personalized. With a strong commitment to delivering high-quality services, the Behavioral Health Clinic is focused on supporting clients on their journey to lasting recovery.

Alpha Omega Counseling Center
+7 photos

Alpha Omega Counseling Center

Danville, IL

Situated in Danville, IL, the Alpha Omega Counseling Center provides an extensive variety of substance use treatments for both adults and children/adolescents facing serious mental health challenges. They offer intensive outpatient, outpatient, and regular outpatient programs that incorporate 12-step facilitation, anger management, and brief intervention strategies. This facility recognizes the unique needs of various groups by offering specialized programs for active duty military personnel as well as separate programs for adult men and women. By delivering personalized care for both genders, the center fosters a supportive and effective rehabilitation atmosphere. When seeking quality treatment and compassionate support on the road to recovery, consider the Alpha Omega Counseling Center.

Pecan Haven Addiction Recovery Center
+7 photos

Pecan Haven Addiction Recovery Center

Monroe, LA

Situated in Monroe, LA, Pecan Haven Addiction Recovery Center provides an extensive variety of treatment options tailored for adults dealing with substance use disorders alongside co-occurring mental health issues. The center features intensive outpatient programs, long-term residential care, and standard outpatient services, incorporating methodologies like 12-step facilitation, anger management, and brief interventions. Pecan Haven has dedicated programs designed for adult men and women, accommodating various age groups, including both adults and young adults. Placing a strong emphasis on personalized care and evidence-based practices, this facility creates a welcoming atmosphere for all clients—male and female alike—who are on their journey to recovery from addiction.

Tools for Life Ltd
+7 photos

Tools for Life Ltd

Aurora, IL

Situated in Aurora, IL, Tools for Life Ltd provides a variety of evidence-based treatment options for both substance use and concurrent mental health challenges affecting adults and children. The center offers several levels of care, including intensive outpatient, outpatient, and regular outpatient programs, all designed to meet the unique needs of each individual. In addition to standard services, the facility features specialized programs aimed at adolescents, survivors of intimate partner violence, and forensic clients, ensuring that all patients receive the right level of targeted support. With a range of therapeutic approaches like 12-step facilitation, anger management, and brief intervention, Tools for Life Ltd is committed to providing personalized care tailored for both male and female clients. Discover quality treatment and compassionate support at Tools for Life Ltd.

Braden Counseling Center PC
+7 photos

Braden Counseling Center PC

Sycamore, IL

Braden Counseling Center PC, located in Sycamore, IL, specializes in providing substance use treatment for both adults and children who are facing serious mental health challenges or emotional disturbances. The center offers various levels of care, including intensive outpatient, outpatient, and regular outpatient programs. Their treatment methods incorporate evidence-based strategies like anger management, brief intervention, and cognitive behavioral therapy. At Braden Counseling Center, the emphasis is on personalized care, allowing for programs that are customized to fit the individual needs of each client. They serve both men and women, promoting an inclusive approach to rehabilitation. Here, you can expect compassionate and effective support, with a strong commitment to delivering high-quality treatment.

Madera County Behav Health Services
+7 photos

Madera County Behav Health Services

Madera, CA

Madera County Behavioral Health Services, located in Madera, CA, offers a wide range of substance use treatments along with specialized care for those facing both substance use issues and serious mental health challenges. They provide various treatment options, including intensive outpatient, outpatient, and regular outpatient programs. The facility emphasizes brief intervention techniques, cognitive behavioral therapy, and motivational incentives through contingency management, ensuring that care is tailored specifically for both adults and children/adolescents. They also have specialized programs designed for adolescents, adult men, and adult women. With a focus on gender-specific services, the center fosters a supportive atmosphere that helps both male and female clients feel at ease. For quality care and personalized support, Madera County Behavioral Health Services is here to help.

Four Corners Detox Recovery Center
+7 photos

Four Corners Detox Recovery Center

Gallup, NM

Four Corners Detox Recovery Center, situated in Gallup, NM, provides a wide array of services for individuals battling addiction. The facility specializes in detoxification and substance use treatment, along with targeted support for those facing both substance use issues and serious mental health conditions. Their offerings include intensive outpatient treatment, long-term residential care, and various outpatient services. With a commitment to personalized care, the center employs approaches such as 12-step facilitation, cognitive behavioral therapy, and the Matrix Model, ensuring that treatment plans are customized to fit each person's unique needs. Additionally, they offer specialized programs for active duty military personnel, as well as distinct options for adult men and women. Four Corners Detox Recovery Center proudly serves adults and young adults of all genders, wholeheartedly dedicated to delivering high-quality care and assistance to individuals on their journey to recovery from addiction.

Halyard Behavioral Health and Wellness
+7 photos

Halyard Behavioral Health and Wellness

Baltimore, MD

Halyard Behavioral Health and Wellness, situated in Baltimore, MD, provides an extensive array of services designed to tackle substance use disorders and co-occurring mental health issues for both adults and children. The center features a variety of treatment options, including intensive outpatient programs, long-term residential care, and standard outpatient services. They employ a range of therapeutic approaches such as 12-step facilitation, anger management, and brief intervention techniques. This facility recognizes the unique needs of different age groups and genders, with specialized programs available for adolescents, adult men, and adult women. Additionally, Halyard offers transitional housing and sober living arrangements, ensuring that individuals, including adults and seniors, receive tailored care and robust support on their journey to recovery.

Hudson Behavioral Health
+7 photos

Hudson Behavioral Health

Salisbury, MD

Located in Salisbury, MD, Hudson Behavioral Health specializes in detoxification and substance use treatment services. They offer hospital inpatient detoxification alongside a range of treatment options, all with round-the-clock care. The facility emphasizes a variety of therapeutic approaches, including 12-step facilitation, brief intervention, and cognitive behavioral therapy, tailored for adult men and women, as well as individuals who have faced trauma. Catering to both adults and young adults of all genders, Hudson Behavioral Health is committed to providing personalized care and support. With its comprehensive range of programs and a strong focus on quality, this center stands out as an excellent choice for those seeking effective and compassionate addiction treatment.

Northstar Recovery Center
+7 photos

Northstar Recovery Center

West Springfield, MA

Located in West Springfield, MA, Northstar Recovery Center specializes in providing thorough substance use treatment tailored for both adults and young adults who are also facing co-occurring mental health issues. The center offers a range of programs, including intensive outpatient treatment, outpatient day treatment, and partial hospitalization options. With a focus on serving diverse groups, Northstar features specialized services for active duty military personnel, as well as programs designed for adult men and women. By incorporating approaches like 12-step facilitation, anger management, and brief interventions, the facility ensures that each client receives personalized care. Northstar Recovery Center is dedicated to delivering high-quality support for individuals on their journey to overcome addiction and navigate dual diagnosis challenges, regardless of gender.

Insight Treatment Programs
+7 photos

Insight Treatment Programs

Santa Clarita, CA

Located in Santa Clarita, CA, Insight Treatment Programs specializes in addressing substance use issues as well as co-occurring disorders for both adults and children. They offer a range of options, including intensive outpatient, outpatient, and partial hospitalization programs. Their approach emphasizes 12-step facilitation, anger management, and brief intervention strategies. Notably, the facility has tailored programs designed specifically for adolescents and clients who face dual diagnoses. Catering to individuals of all genders—from young children to adults—Insight Treatment Programs places a strong emphasis on personalized care and evidence-based practices to enhance recovery. With a steadfast commitment to providing quality treatment, this center stands as a beacon of hope for anyone in need of comprehensive rehabilitation services.

Queen of Peace Center
+7 photos

Queen of Peace Center

Saint Louis, MO

The Queen of Peace Center, located in Saint Louis, MO, specializes in rehabilitation programs designed specifically for adult women who are addressing substance use issues alongside co-occurring mental health disorders. The center offers a comprehensive range of services, such as intensive outpatient treatment, transitional housing, and outpatient day treatment. Emphasizing anger management, brief intervention, and motivational incentives, this facility customizes its approach to cater to the unique experiences of clients who have faced trauma. With a focus on adults, seniors, and young adults, Queen of Peace Center is distinguished by its dedication to delivering high-quality care within a nurturing, female-focused environment.

Isaiah House
+7 photos

Isaiah House

Willisburg, KY

Isaiah House, situated in Willisburg, KY, provides a variety of comprehensive rehabilitation services aimed at adult men who are on the path to recovery from substance use. With a strong emphasis on long-term residential programs, the facility offers detoxification and transitional housing, ensuring that clients receive round-the-clock care. The center has specialized programs designed specifically for active duty military personnel, adult men, and those who have faced intimate partner violence. In its commitment to helping individuals achieve sobriety, Isaiah House employs evidence-based strategies, including 12-step facilitation and anger management techniques. Welcoming adults, seniors, and young adults, this facility creates a nurturing environment exclusively for male clients. Experience the difference with personalized care and tailored treatment at Isaiah House.

About Depression Treatment

Depression and substance use often occur together, with each condition potentially worsening the other. At Penn Spine and Rehab, we help individuals find treatment programs that address both depression and addiction simultaneously for the best possible outcomes.

The Connection Between Depression and Addiction

Many people with depression turn to alcohol or drugs to cope with painful feelings, while substance use itself can cause or worsen depressive symptoms. This complex relationship requires integrated treatment that addresses both conditions.

Signs of co-occurring depression and substance use include:

  • Persistent feelings of sadness, emptiness, or hopelessness
  • Loss of interest in previously enjoyed activities
  • Using substances to cope with difficult emotions
  • Worsening depression despite substance use
  • Difficulty functioning at work, school, or in relationships

Integrated Treatment Approaches

Dual diagnosis treatment programs offer comprehensive care including:

Finding the Right Program

Look for treatment centers with psychiatrists and mental health professionals on staff, not just addiction counselors. Residential programs often provide the intensive support needed to stabilize both conditions, while ongoing outpatient care maintains progress.

Causes & Risk Factors for Depression

Depression develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Neurochemical overlap — both depression and addiction involve serotonin and dopamine dysregulation
  • •Self-medication — using substances to numb emotional pain, hopelessness, or fatigue
  • •Substance-induced depression — chronic alcohol or drug use depletes mood-regulating neurotransmitters
  • •Genetic predisposition — shared hereditary risk factors for both conditions
  • •Childhood trauma and adverse experiences
  • •Chronic stress, grief, loss, or major life changes
  • •Social isolation — both depression and addiction worsen with loneliness

Depression Statistics

21M

US adults had at least one major depressive episode in 2021

Source: NIMH

33%

Of people with major depression also have a substance use disorder

Source: JAMA

63%

Of people with alcohol dependence have a history of depression

Source: NIAAA

2x

People with depression are twice as likely to develop addiction

Source: NIDA

48K+

Suicides in the US in 2021 — substance use is a major risk factor

Source: CDC

40%

Improvement in addiction outcomes when depression is treated concurrently

Source: SAMHSA

What to Expect in Depression Treatment

1

Comprehensive Assessment (Days 1-3)

Psychiatric evaluation and substance use assessment. PHQ-9 depression screening. Determine if depression is independent or substance-induced. Create integrated treatment plan.

2

Detox & Psychiatric Stabilization (Days 3-10)

Safe withdrawal management. Begin antidepressant medication if indicated (SSRIs may take 2-4 weeks for full effect). Monitor suicidal ideation. Comfort care and sleep hygiene.

3

Active Integrated Treatment (Weeks 2-8)

CBT targeting both depressive thinking patterns and addiction triggers. Behavioral activation to counter depression-related withdrawal. Group therapy. Medication optimization.

4

Skill Building & Recovery Planning (Weeks 8-12)

Relapse prevention for both conditions. Healthy routine development (exercise, sleep, nutrition). Family therapy. Building social support network beyond substances.

5

Aftercare & Maintenance (Ongoing)

Continued antidepressant management with psychiatrist. Step-down to outpatient therapy. Peer support groups. Ongoing monitoring of mood and cravings. Safety planning.

Frequently Asked Questions About Depression Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Depression & Addiction Treatment | Penn Spine and Rehab