Penn Spine and Rehab Logo

Depression Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Depression treatment within addiction recovery takes an integrated approach to address both conditions simultaneously. Evidence-based therapies like CBT and DBT, medication management when appropriate, and holistic wellness practices help individuals manage depressive symptoms while building a strong foundation for lasting sobriety.

Found 8,160 rehab centers specializing in depression across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(223) 235-7839
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 8160 depression rehab centers

Narconon Pacific Coast
+2 photos

Narconon Pacific Coast

Ojai, CA

Narconon Pacific Coast, situated in Ojai, CA, provides long-term residential treatment for substance use, employing a well-rounded methodology. This facility caters specifically to active duty military personnel, as well as adult men and women. Designed for both adults and young adults of any gender, Narconon Pacific Coast is dedicated to delivering high-quality care through its around-the-clock residential program. With an emphasis on personalized treatment and support, this center distinguishes itself by focusing on helping individuals conquer addiction and achieve sustained recovery. If you’re in search of effective, tailored substance use treatment, Narconon Pacific Coast is worth considering for its comprehensive care in a nurturing environment.

Samadhi Center Inc
+2 photos

Samadhi Center Inc

Kingston, NY

Located in Kingston, NY, Samadhi Center Inc provides outpatient treatment for substance use and specialized support for adults facing co-occurring substance use and serious mental health issues, as well as children dealing with emotional disturbances. The center offers a range of outpatient services, including day treatment programs, methadone and buprenorphine therapy, and cognitive behavioral therapy, ensuring that individuals receive comprehensive support. They have unique programs specifically designed for active duty military personnel, adolescents, and adult men. Serving individuals of all ages and genders, including adults, children, and young adults, the center places a strong emphasis on anger management and brief interventions, tailoring their approach to meet each person's needs. At Samadhi Center Inc, the focus is on delivering high-quality treatment for those in search of effective and personalized rehabilitation services.

BHG Staunton Treatment Center
+2 photos

BHG Staunton Treatment Center

Staunton, VA

BHG Staunton Treatment Center, situated in Staunton, VA, provides a range of outpatient services, including detoxification, substance use treatment, and outpatient options for methadone, buprenorphine, or naltrexone for both adults and young adults. The center emphasizes various therapeutic approaches, including 12-step facilitation, anger management, and brief interventions. BHG Staunton is dedicated to offering personalized care for clients who've faced trauma, as well as those living with HIV or AIDS, and individuals dealing with both mental health and substance use disorders. With an emphasis on gender-specific treatment for both men and women, this facility is committed to delivering high-quality support to individuals as they navigate their recovery journey.

Fred Browns Recovery Services Inc
+2 photos

Fred Browns Recovery Services Inc

San Pedro, CA

Fred Browns Recovery Services Inc, located in San Pedro, CA, provides a wide range of treatment options for adults struggling with substance use and co-occurring mental health issues. Their offerings include intensive outpatient programs, outpatient services, and regular outpatient programs that incorporate methods like 12-step facilitation, anger management, and brief interventions. The center also features specialized programs designed for adult men, women, and individuals facing trauma. Catering to both adults and young adults, they deliver customized care for clients of all genders. At this San Pedro facility, the emphasis is on personalized treatment and evidence-based practices, ensuring that individuals seeking help for substance use and mental health challenges receive top-notch care.

Lower Shore Clinic Inc
+2 photos

Lower Shore Clinic Inc

Salisbury, MD

Situated in Salisbury, MD, Lower Shore Clinic Inc offers a wide array of outpatient services designed for those in need of substance use treatment and recovery. The clinic focuses on detoxification as well as addressing both substance use and mental health issues for both adults and children. Emphasizing outpatient detoxification, the center employs methadone and buprenorphine therapies, utilizing evidence-based methods such as cognitive behavioral therapy and anger management techniques. Additionally, Lower Shore Clinic Inc is attentive to clients who have experienced trauma or sexual abuse, creating a safe and nurturing environment conducive to healing. Aiming to serve adults and young adults of all genders, this facility is dedicated to providing top-notch care to assist individuals on their path to recovery.

List Psychological Services PLC
+2 photos

List Psychological Services PLC

Lapeer, MI

List Psychological Services PLC, located in Lapeer, MI, offers specialized outpatient treatment designed for both adults and children dealing with substance use issues and co-occurring mental health conditions. The center employs various techniques, including anger management, cognitive behavioral therapy, and brief interventions, ensuring that care is customized to meet each individual's unique needs. They also provide distinctive programs specifically for trauma survivors and those involved with the criminal justice system. With a commitment to serving adults and seniors of all genders, this facility is dedicated to delivering expert care in a welcoming atmosphere. If you’re looking for quality rehabilitation services in a supportive environment, List Psychological Services PLC could be your go-to choice for comprehensive and effective treatment.

Mirmont Outpatient Center
+2 photos

Mirmont Outpatient Center

Exton, PA

The Mirmont Outpatient Center, situated in Exton, PA, is dedicated to providing specialized treatment for adults facing significant mental health challenges, as well as children grappling with emotional disturbances. They offer intensive outpatient and day treatment programs that are grounded in proven methods, including cognitive behavioral therapy and motivational interviewing. With a particular emphasis on adolescents and clients involved in the criminal justice system, this facility crafts personalized care plans for both males and females. The center's unwavering commitment to quality and individualized treatment positions it as a premier option for anyone in the Exton area seeking comprehensive rehabilitation services.

Treatment Centers LLC
+2 photos

Treatment Centers LLC

Salisbury, NC

Located in Salisbury, NC, Treatment Centers LLC specializes in a wide range of substance use treatment for both adults and young adults. They offer outpatient services, which include methadone, buprenorphine, and naltrexone treatments, as well as regular outpatient programs. The focus is on personalized care, utilizing techniques like brief intervention, cognitive behavioral therapy, and motivational interviewing to meet the unique needs of each client. The center features distinctive programs designed specifically for adult men and women, as well as for clients who have faced intimate partner or domestic violence. They create a welcoming and supportive atmosphere that serves both male and female clients alike. At Treatment Centers LLC, you can expect excellent care accompanied by specialized programs tailored just for you.

New Connections
+2 photos

New Connections

Lemon Grove, CA

New Connections, situated in Lemon Grove, CA, provides a variety of evidence-based rehabilitation services. This center is dedicated to treating substance use issues and co-occurring disorders for both adults and children. They offer several treatment formats, including long-term residential programs, outpatient services, and 24-hour residential care. With an emphasis on 12-step facilitation, anger management, and brief interventions, New Connections delivers customized care for adult men and women, along with those who have faced domestic violence. Catering to individuals of all genders, this facility is passionate about offering high-quality, personalized support to help everyone on their journey to recovery.

Volunteers of America Northern Rockies
+2 photos

Volunteers of America Northern Rockies

Torrington, WY

In the heart of Torrington, WY, Volunteers of America Northern Rockies provides exceptional rehabilitation services for both adults and seniors facing challenges with substance use disorders alongside co-occurring mental health issues. The facility specializes in various treatment options, including intensive outpatient programs, outpatient care, and targeted therapies using methadone, buprenorphine, or naltrexone. With a strong emphasis on anger management, brief intervention strategies, and cognitive behavioral therapy, this center serves adult men, adult women, and adolescents alike. Their customized programs are designed to meet the unique needs of each client, ensuring high-quality care for everyone. This makes the facility a crucial resource for individuals seeking thorough and effective addiction support.

Aware Recovery Care of Maine
+2 photos

Aware Recovery Care of Maine

South Portland, ME

Situated in South Portland, ME, Aware Recovery Care of Maine delivers a wide array of addiction treatment services. This center specializes in detoxification and substance use treatment, offering intensive outpatient, outpatient, and detox programs tailored to meet the needs of each individual. Employing a variety of techniques, including brief interventions, cognitive behavioral therapy, and the Matrix Model, the facility adapts its services to suit unique personal circumstances. Aware Recovery Care of Maine focuses on providing care to adults, children, and adolescents across all genders, emphasizing a personalized, individualized approach. With a strong commitment to quality treatment, this center is dedicated to supporting individuals as they navigate their journey to recovery.

Personal Counseling Services
+2 photos

Personal Counseling Services

Springfield, IL

Located in Springfield, IL, Personal Counseling Services delivers a complete range of substance use treatment alongside specialized support for those facing co-occurring mental health challenges. Their offerings include intensive outpatient programs, standard outpatient services, and regular outpatient treatment, employing various techniques like 12-step facilitation, anger management, and brief intervention strategies. This facility is especially attentive to the unique needs of adult women, survivors of sexual abuse, and individuals living with HIV or AIDS, tailoring programs to address their specific circumstances. Catering to a diverse clientele that includes adults, children, adolescents, and seniors of all genders, the center prioritizes personalized care and dedicated support for anyone who is on the path to recovery.

ARS Treatment Centers of New Jersey
+2 photos

ARS Treatment Centers of New Jersey

Lanoka Harbor, NJ

Situated in Lanoka Harbor, NJ, ARS Treatment Centers of New Jersey provides outpatient treatment for adults and young adults dealing with substance use issues. The facility features specialized programs designed specifically for pregnant and postpartum women. With an emphasis on counseling for substance use disorders, the center also offers telemedicine and telehealth therapy options. Both male and female clients can benefit from personalized outpatient treatments with methadone, buprenorphine, or naltrexone. ARS Treatment Centers of New Jersey is committed to delivering high-quality care and support for individuals on their journey to recovery from addiction, making it an essential resource for those seeking comprehensive and gender-sensitive treatment alternatives in the region.

SalusCare
+2 photos

SalusCare

Fort Myers, FL

Located in Fort Myers, FL, SalusCare provides a wide range of addiction treatment services designed for both adults and young adults. The center features long-term residential programs, outpatient care, and day treatment options, all grounded in evidence-based practices. These approaches include 12-step facilitation, anger management, and cognitive behavioral therapy. SalusCare also has specialized programs aimed at individuals facing co-occurring substance use and mental health disorders, trauma survivors, and those who have endured intimate partner violence or sexual abuse. To further support individuals on their journey to recovery, transitional housing options are available. With a strong emphasis on quality care, this facility tailors its treatment to meet the unique needs of both male and female clients as they work toward overcoming addiction and mental health challenges.

Portland Community Health Center
+2 photos

Portland Community Health Center

Portland, ME

Portland Community Health Center, located in Portland, ME, provides extensive outpatient substance use treatment designed for adults and young adults, particularly those dealing with co-occurring serious mental health issues or emotional challenges. The center also features specialized programs aimed specifically at clients living with HIV or AIDS. Using evidence-based methods such as cognitive behavioral therapy and motivational incentives, this facility ensures that care is both effective and tailored to the unique needs of each individual. Treatment options available include outpatient programs utilizing methadone/buprenorphine or naltrexone. With an emphasis on brief interventions and personalized care, Portland Community Health Center is dedicated to offering effective and compassionate addiction recovery services to both male and female clients.

Serenity Health
+2 photos

Serenity Health

Elkton, MD

Serenity Health, situated in Elkton, MD, specializes in offering a wide range of addiction treatment services designed for both adults and young adults. The facility features intensive outpatient treatment, outpatient programs, and detoxification services for those seeking help. Emphasizing methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, the center serves both male and female clients. Additionally, Serenity Health offers unique programs specifically crafted for adult men, adult women, and individuals who have endured intimate partner violence or domestic violence. The center is committed to delivering quality care and support for anyone on their journey to recovery from substance use disorders.

Alcohol and Drug Abuse Council of
+2 photos

Alcohol and Drug Abuse Council of

Lufkin, TX

Situated in Lufkin, TX, the Alcohol and Drug Abuse Council provides outpatient treatment options for substance use issues tailored to both adults and adolescents. The facility employs various methods, including brief intervention, the Matrix Model, and motivational interviewing, to deliver specialized programs for adult men, adult women, and young people. By accommodating individuals of all genders, this center commits to offering effective care for those seeking to overcome alcohol and drug addiction. With an emphasis on creating personalized treatment plans, the center is dedicated to supporting each client on their path to sobriety. If you or someone you care about is in need of professional addiction treatment services, be sure to explore the comprehensive programs available at this facility.

One Promise Behavioral health
+2 photos

One Promise Behavioral health

Baltimore, MD

Located in Baltimore, MD, One Promise Behavioral Health specializes in addiction treatment services designed specifically for adults and young adults. The center offers a comprehensive range of options, including detoxification, intensive outpatient programs, outpatient services, and outpatient day treatment. Focusing on methods such as 12-step facilitation, anger management, and brief interventions, One Promise Behavioral Health customizes its approach to meet each individual's needs effectively. They also provide distinct programs tailored for adult men, adult women, and individuals who have dealt with intimate partner violence or domestic violence. With a commitment to delivering quality care for both male and female clients, One Promise Behavioral Health combines professionalism with a compassionate approach to treatment.

Western Tidewater Community Services
+2 photos

Western Tidewater Community Services

Suffolk, VA

Western Tidewater Community Services, located in Suffolk, VA, provides a wide variety of outpatient services designed for detoxification, treatment for substance use, and addressing co-occurring disorders in both adults and children. This facility employs methods such as cognitive behavioral therapy and motivational interviewing, emphasizing personalized care that caters to the unique needs of each client. With an emphasis on anger management and custom programs, individuals of all genders, including adults and seniors, can expect high-quality treatment. Those in search of a supportive and effective atmosphere for their recovery will find that Western Tidewater Community Services offers a professional and compassionate environment to assist in their healing journey.

Southwestern Behavioral Care Inc
+2 photos

Southwestern Behavioral Care Inc

Latrobe, PA

Located in Latrobe, PA, Southwestern Behavioral Care Inc provides an extensive array of substance use treatments, with a special focus on addressing co-occurring substance use disorders and serious mental health issues among adults. Additionally, the center offers support for emotional disturbances in children. This facility features various treatment options, including intensive outpatient programs, outpatient care, and day treatment, tailored to meet the diverse needs of its clients. With an emphasis on 12-step facilitation, anger management, and brief intervention strategies, they serve adult men and women, as well as individuals who have faced sexual abuse. Committed to delivering personalized care, Southwestern Behavioral Care Inc works with both adults and children/adolescents of all genders, fostering a quality treatment environment that prioritizes support and understanding.

About Depression Treatment

Depression and substance use often occur together, with each condition potentially worsening the other. At Penn Spine and Rehab, we help individuals find treatment programs that address both depression and addiction simultaneously for the best possible outcomes.

The Connection Between Depression and Addiction

Many people with depression turn to alcohol or drugs to cope with painful feelings, while substance use itself can cause or worsen depressive symptoms. This complex relationship requires integrated treatment that addresses both conditions.

Signs of co-occurring depression and substance use include:

  • Persistent feelings of sadness, emptiness, or hopelessness
  • Loss of interest in previously enjoyed activities
  • Using substances to cope with difficult emotions
  • Worsening depression despite substance use
  • Difficulty functioning at work, school, or in relationships

Integrated Treatment Approaches

Dual diagnosis treatment programs offer comprehensive care including:

Finding the Right Program

Look for treatment centers with psychiatrists and mental health professionals on staff, not just addiction counselors. Residential programs often provide the intensive support needed to stabilize both conditions, while ongoing outpatient care maintains progress.

Causes & Risk Factors for Depression

Depression develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • Neurochemical overlap — both depression and addiction involve serotonin and dopamine dysregulation
  • Self-medication — using substances to numb emotional pain, hopelessness, or fatigue
  • Substance-induced depression — chronic alcohol or drug use depletes mood-regulating neurotransmitters
  • Genetic predisposition — shared hereditary risk factors for both conditions
  • Childhood trauma and adverse experiences
  • Chronic stress, grief, loss, or major life changes
  • Social isolation — both depression and addiction worsen with loneliness

Depression Statistics

21M

US adults had at least one major depressive episode in 2021

Source: NIMH

33%

Of people with major depression also have a substance use disorder

Source: JAMA

63%

Of people with alcohol dependence have a history of depression

Source: NIAAA

2x

People with depression are twice as likely to develop addiction

Source: NIDA

48K+

Suicides in the US in 2021 — substance use is a major risk factor

Source: CDC

40%

Improvement in addiction outcomes when depression is treated concurrently

Source: SAMHSA

What to Expect in Depression Treatment

1

Comprehensive Assessment (Days 1-3)

Psychiatric evaluation and substance use assessment. PHQ-9 depression screening. Determine if depression is independent or substance-induced. Create integrated treatment plan.

2

Detox & Psychiatric Stabilization (Days 3-10)

Safe withdrawal management. Begin antidepressant medication if indicated (SSRIs may take 2-4 weeks for full effect). Monitor suicidal ideation. Comfort care and sleep hygiene.

3

Active Integrated Treatment (Weeks 2-8)

CBT targeting both depressive thinking patterns and addiction triggers. Behavioral activation to counter depression-related withdrawal. Group therapy. Medication optimization.

4

Skill Building & Recovery Planning (Weeks 8-12)

Relapse prevention for both conditions. Healthy routine development (exercise, sleep, nutrition). Family therapy. Building social support network beyond substances.

5

Aftercare & Maintenance (Ongoing)

Continued antidepressant management with psychiatrist. Step-down to outpatient therapy. Peer support groups. Ongoing monitoring of mood and cravings. Safety planning.

Frequently Asked Questions About Depression Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Depression & Addiction Treatment | Penn Spine and Rehab