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Dual Diagnosis Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Dual diagnosis treatment provides integrated, simultaneous care for individuals with co-occurring mental health and substance use disorders. This comprehensive approach recognizes that treating both conditions together leads to better outcomes than addressing them separately, with specialized staff trained in both addiction and mental health treatment.

Found 7,434 rehab centers specializing in dual diagnosis across the United States.

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Showing 20 of 7434 dual diagnosis rehab centers

Centerstone of Indiana Inc
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Centerstone of Indiana Inc

Indianapolis, IN

Centerstone of Indiana Inc, located in Indianapolis, IN, provides outpatient treatment for adults dealing with substance use issues alongside serious mental health challenges. They cater to children experiencing emotional disturbances as well. Their offerings feature programs such as anger management, brief interventions, and cognitive behavioral therapy. The facility is equipped to serve both adult men and women, and also focuses on assisting clients who have faced intimate partner or domestic violence. Committed to adults and young adults of all genders, Centerstone emphasizes comprehensive, personalized care to meet the distinct needs of every individual. If you're looking for quality rehabilitation services, consider Centerstone of Indiana Inc.

CentraCare/Saint Cloud Hospital
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CentraCare/Saint Cloud Hospital

Saint Cloud, MN

CentraCare/Saint Cloud Hospital, located in Saint Cloud, MN, offers a wide array of rehabilitation services designed for adults and young adults who are dealing with substance use issues. This facility is particularly skilled at addressing co-occurring substance use disorders in tandem with serious mental health conditions or emotional challenges in children. The center provides various treatment options, such as intensive outpatient care and outpatient day programs. Their tailored approaches include 12-step facilitation and anger management, among others. What's more, they have specialized programs aimed at seniors and older adults, ensuring that everyone receives personalized care tailored to their specific needs. With a strong emphasis on quality and individualized support, CentraCare/Saint Cloud Hospital has established itself as a reliable choice for those in search of effective addiction treatment solutions.

Centerstone of Indiana Inc
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Centerstone of Indiana Inc

Lexington, IN

Centerstone of Indiana Inc, located in Lexington, IN, provides a wide range of residential treatment options for both substance use issues and co-occurring mental health disorders in adults and children. Their programs include evidence-based methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. This facility is particularly dedicated to serving adult women, including those who have experienced intimate partner violence, domestic violence, and sexual abuse. By emphasizing personalized and high-quality care, Centerstone of Indiana Inc focuses on supporting adult, senior, and young adult females on their journey to recovery.

Centerstone of Indiana Inc
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Centerstone of Indiana Inc

Lexington, IN

Centerstone of Indiana Inc, located in Lexington, IN, offers a wide range of substance use treatment and transitional housing services within a long-term residential environment. This facility focuses on addressing co-occurring substance use disorders alongside serious mental health challenges in adults, as well as serious emotional disturbances in children. With a variety of therapeutic methods, including 12-step facilitation, anger management, and cognitive behavioral therapy, the program is specifically designed for adult women who have faced intimate partner violence, domestic violence, or sexual abuse. Catering primarily to adults, seniors, and young adults—especially females—this center emphasizes personalized care and support, guiding clients on their path to recovery.

Centerstone of Indiana Inc
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Centerstone of Indiana Inc

Columbus, IN

Centerstone of Indiana Inc, located in Columbus, IN, provides a wide range of treatment services for individuals dealing with substance use issues alongside serious mental health conditions or emotional struggles. At this facility, you can find various treatment options, including intensive outpatient and outpatient programs, as well as methadone/buprenorphine or naltrexone therapies. The center employs various methods, such as anger management, brief interventions, and cognitive behavioral therapy, tailoring its services to fit each person's unique needs. They also offer specialized programs aimed at adolescents, adult men, and adult women. Committed to serving both adults and seniors of all genders, Centerstone of Indiana Inc focuses on delivering quality care and support for those on their journey to recovery from addiction and mental health difficulties.

Centerstone of Indiana Inc
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Centerstone of Indiana Inc

Richmond, IN

Centerstone of Indiana Inc, located in Richmond, IN, provides targeted residential treatment programs for adult men who are facing substance use disorders alongside serious mental health conditions or emotional challenges. The center emphasizes techniques such as 12-step facilitation, anger management, and cognitive behavioral therapy, ensuring clients receive personalized care, particularly those who have encountered trauma, intimate partner violence, or domestic violence. Serving a range of age groups including adults, seniors, and young adults, the facility features short-term and round-the-clock residential services, with a specific focus on male clients. With its well-rounded approach and specialized offerings, this center stands out as an excellent option for individuals seeking effective support for complex addiction and mental health issues.

Centerstone of Indiana Inc
+1 photos

Centerstone of Indiana Inc

Scottsburg, IN

Centerstone of Indiana Inc, located in Scottsburg, IN, provides a wide variety of outpatient treatment programs designed to address both substance use and co-occurring mental health issues. Among the specialized services offered are outpatient treatments with methadone, buprenorphine, or naltrexone, alongside anger management, brief interventions, and cognitive behavioral therapy. This facility serves adult men and women, including those who have faced intimate partner or domestic violence. With a clear focus on adults and seniors across all genders, Centerstone ensures personalized care that aligns with each individual's needs. Patients can anticipate receiving high-quality, evidence-based treatment from a team of experienced professionals in a nurturing and supportive atmosphere.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Richmond, IN

Centerstone of Indiana Inc, located in Richmond, IN, specializes in outpatient treatment for substance use, with a particular emphasis on addressing co-occurring serious mental health issues and emotional challenges in both adults and children. The facility offers consistent outpatient services employing various methods, including anger management, brief interventions, and cognitive behavioral therapy. Additionally, it features specialized programs for adult men and women, as well as individuals who have faced intimate partner or domestic violence. The center is committed to providing quality care to adults and young adults of all genders, delivering customized programs that cater to individual needs and promote long-term recovery.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Bedford, IN

Centerstone of Indiana Inc, located in Bedford, IN, provides outpatient treatment aimed at adults facing substance use challenges and co-occurring severe mental health issues, as well as supporting children with serious emotional disturbances. The center specializes in several areas, including anger management, brief interventions, and cognitive behavioral therapy. It offers personalized care for adult men and women, seniors, and those who have encountered intimate partner or domestic violence. With programs tailored for both men and women, this facility is dedicated to delivering inclusive support for a wide variety of individuals in need of effective rehabilitation services.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Bloomington, IN

Centerstone of Indiana Inc, located in Bloomington, IN, provides thorough substance use treatment for adults who are dealing with co-occurring mental health issues, as well as for children experiencing serious emotional challenges. Their specialized outpatient programs feature a variety of options, including 12-step facilitation, anger management, and brief interventions tailored to individual needs. This facility is committed to offering personalized care for adolescents, adult men, and women. Catering to adults and seniors of all genders, they provide outpatient treatment options with methadone, buprenorphine, or naltrexone. Centerstone of Indiana Inc focuses on delivering high-quality care and develops individualized treatment plans, all aimed at supporting clients on their journey toward lasting recovery.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Greensburg, IN

Located in Greensburg, IN, Centerstone of Indiana Inc provides a robust range of substance use treatment options for adults facing co-occurring serious mental health conditions, as well as for children struggling with significant emotional disturbances. The facility offers various outpatient services that include treatments such as methadone, buprenorphine, or naltrexone, alongside cognitive behavioral therapy. The center also features specialized programs tailored for adult men and women, particularly for those who have been affected by intimate partner or domestic violence. Catering to adults and seniors of all genders, Centerstone emphasizes anger management, brief interventions, and personalized care strategies aimed at fostering lasting recovery. With a strong dedication to quality and the implementation of evidence-based practices, Centerstone of Indiana Inc is committed to guiding individuals along their path to wellness.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Muncie, IN

Centerstone of Indiana Inc, located in Muncie, IN, offers a wide array of substance use treatment options for both adults and children facing serious mental health challenges. The center provides outpatient and regular outpatient programs, with a focus on anger management, brief interventions, and cognitive behavioral therapy. They have tailored programs specifically designed for adolescents, adult men, and adult women, catering to a diverse clientele. By serving adults and seniors of all genders, Centerstone prioritizes quality care and effective treatment methods. For those in need of specialized care for substance use and mental health issues, Centerstone of Indiana Inc in Muncie stands out as a reliable option.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Bloomington, IN

Located in Bloomington, IN, Centerstone of Indiana Inc specializes in rehabilitation services tailored for adult men facing challenges with substance use disorders alongside serious mental health conditions. Their offerings include both residential and short-term residential programs that utilize evidence-based methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Additionally, the facility provides unique programs designed specifically for individuals who have encountered trauma, intimate partner violence, or domestic violence. Aiming to serve adult, senior, and young adult males, Centerstone prioritizes quality care and custom treatment plans to foster recovery and promote holistic healing.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Mooresville, IN

Located in Mooresville, IN, Centerstone of Indiana Inc specializes in outpatient substance use treatment and offers targeted care for individuals facing both substance use issues and significant mental health conditions. The facility features regular outpatient programs that incorporate a variety of techniques, including anger management, brief intervention, and cognitive behavioral therapy. Additionally, they have specialized programs designed for adolescents, adult men, and adult women, accommodating a wide spectrum of clients. Catering to both adults and seniors across genders, Centerstone of Indiana Inc is committed to delivering high-quality care and extensive support for individuals aiming to overcome addiction and mental health obstacles.

Centerstone of Indiana Inc

Centerstone of Indiana Inc

Madison, IN

Located in Madison, IN, Centerstone of Indiana Inc provides extensive outpatient treatment for both adults and children dealing with substance use issues, especially those who also face co-occurring mental health concerns. Their range of programs features anger management, cognitive behavioral therapy, and dedicated services for individuals impacted by domestic violence. This facility offers outpatient treatments using methadone, buprenorphine, or naltrexone, alongside tailored outpatient care designed to meet the specific needs of men and women. Committed to delivering high-quality care and personalized treatment plans, Centerstone of Indiana Inc supports adults and seniors of all genders on their journey toward recovery from substance use disorders and mental health difficulties.

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Centerstone of Indiana Inc

Rushville, IN

Centerstone of Indiana Inc, located in Rushville, IN, specializes in outpatient treatment for substance use disorders and offers dedicated care for individuals with co-occurring conditions, whether that's a serious mental health issue in adults or significant emotional disturbances in children. Their treatment methods encompass anger management, brief interventions, and cognitive behavioral therapy. The facility provides outpatient options for methadone/buprenorphine and naltrexone, alongside standard outpatient services. They have designed programs specifically for adult men and women, as well as clients who have faced intimate partner or domestic violence, serving adults and seniors of all genders. With a strong emphasis on personalized care and evidence-based strategies, Centerstone is committed to delivering high-quality treatment for those on their journey to recovery.

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Centerstone of Indiana Inc

Spencer, IN

Centerstone of Indiana Inc, located in Spencer, IN, provides a variety of outpatient treatment programs designed to address substance use disorders as well as co-occurring mental health challenges for both adults and children. The facility offers services like 12-step facilitation, anger management, and brief intervention, all customized to meet the specific needs of each individual. Additionally, the center has programs aimed at adult men, women, and survivors of intimate partner violence, ensuring that they meet the needs of a wide range of demographics. Committed to serving adults and seniors of all genders, Centerstone focuses on providing high-quality, personalized care to aid individuals on their journey to recovery.

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Centerstone of Indiana Inc

Winchester, IN

Centerstone of Indiana Inc, located in Winchester, IN, provides outpatient treatment for adults and children dealing with serious mental health issues and emotional challenges related to substance use. Their offerings include programs for anger management, brief intervention, and cognitive behavioral therapy. This facility is dedicated to delivering specialized care tailored for both men and women, including individuals who have experienced domestic violence or intimate partner violence. Focusing on adults and seniors of all genders, Centerstone of Indiana Inc promotes high-quality treatment within a nurturing environment. If you or someone you know is looking for comprehensive rehabilitation services, this center presents a variety of effective strategies to meet diverse needs.

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Centerstone of Indiana Inc

North Vernon, IN

Centerstone of Indiana Inc, located in North Vernon, IN, provides outpatient treatment for adults dealing with substance use issues alongside co-occurring mental health disorders. Their range of programs includes anger management, brief intervention, and cognitive behavioral therapy. This facility is dedicated to offering specialized care for adolescents as well as adult men and women. By emphasizing personalized treatment plans for both adults and seniors of all genders, Centerstone of Indiana Inc is committed to addressing the unique needs of each individual. Their dedication to delivering high-quality care through a comprehensive approach to substance use and mental health challenges establishes them as a vital resource for those in search of effective rehabilitation services.

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Centerstone of Indiana Inc

Nashville, IN

Centerstone of Indiana Inc, located in Nashville, IN, provides outpatient services for adults struggling with substance use issues alongside serious mental health conditions. This facility specializes in helping children facing significant emotional challenges and offers consistent outpatient care. Their methods include 12-step facilitation, anger management, and brief intervention strategies. With programs specifically designed for adolescents, as well as adult men and women, this center is inclusive, serving both adults and seniors of all genders. Recognized for delivering high-quality care and a range of treatment options, Centerstone of Indiana Inc is a reliable option for individuals looking for effective and personalized addiction treatment within a nurturing setting.

About Dual Diagnosis Treatment

Dual diagnosis—also called co-occurring disorders—refers to having both a mental health condition and a substance use disorder. At Penn Spine and Rehab, we specialize in helping individuals find integrated treatment programs that address both conditions for comprehensive healing.

Why Integrated Treatment Matters

Research consistently shows that treating mental health and substance use disorders together produces better outcomes than treating them separately. When one condition goes untreated, it often triggers relapse in the other.

Common co-occurring mental health conditions include:

What to Look for in a Program

Quality dual diagnosis programs typically offer:

  • Integrated Assessment: Comprehensive evaluation of both conditions
  • Psychiatric Services: On-site psychiatrists for medication management
  • Evidence-Based Therapies: CBT, DBT, and other proven approaches
  • Coordinated Care: Mental health and addiction professionals working together
  • Comprehensive Aftercare: Ongoing support for both conditions

Levels of Care

The appropriate level of care depends on symptom severity and stability. Residential treatment is often recommended for acute symptoms, while partial hospitalization (PHP) or intensive outpatient (IOP) may be appropriate for those with more stable conditions.

Causes & Risk Factors for Dual Diagnosis

Dual Diagnosis develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • •Self-medication — using substances to cope with untreated mental health symptoms
  • •Shared genetic vulnerability — overlapping hereditary risk factors for both conditions
  • •Common brain pathways — both affect dopamine, serotonin, and stress response systems
  • •Childhood trauma and adverse experiences (ACEs) — risk factor for both conditions
  • •Substance-induced mental health changes — chronic use can trigger anxiety, depression, psychosis
  • •Environmental stressors — poverty, isolation, lack of access to mental health care
  • •Disrupted brain development — adolescent substance use during critical periods

Dual Diagnosis Statistics

9.2M

US adults with both mental illness and substance use disorder

Source: SAMHSA

50%

Of people with severe mental illness also have substance use disorder

Source: NAMI

37%

Of people with alcohol use disorder have at least one mental illness

Source: JAMA

53%

Of people with drug use disorder have at least one mental illness

Source: JAMA

60%

Higher relapse rate when only one condition is treated

Source: SAMHSA

45%

Of people in SUD treatment also meet criteria for a mental health disorder

Source: NIDA

What to Expect in Dual Diagnosis Treatment

1

Comprehensive Assessment (Days 1-3)

Thorough evaluation of both mental health and substance use — psychiatric interview, addiction history, medical exam, psychological testing. This determines both diagnoses and creates a unified treatment plan.

2

Stabilization & Detox (Days 3-10)

Medical detox if needed, alongside psychiatric stabilization. Medication management begins for mental health symptoms. Crisis stabilization for acute psychiatric issues.

3

Integrated Intensive Treatment (Weeks 2-8)

Simultaneous treatment: addiction counseling + psychiatric therapy. CBT, DBT, or trauma-focused therapy. Medication optimization. Group therapy with peers who have co-occurring disorders.

4

Skills Building & Relapse Prevention (Weeks 8-12)

Develop coping strategies for both conditions. Identify triggers for both mental health episodes and substance use. Family education. Build recovery community.

5

Continuing Care (Ongoing)

Step-down to outpatient with continued psychiatric medication management. Regular therapy sessions. Peer support groups. Crisis planning for both conditions.

Frequently Asked Questions About Dual Diagnosis Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Dual Diagnosis Treatment Centers | Penn Spine and Rehab