Penn Spine and Rehab Logo

Medication-Assisted Treatment (MAT) Treatment Centers

Medication-Assisted Treatment (MAT) is considered the gold standard for opioid use disorder and is also effective for alcohol addiction. MAT combines FDA-approved medications like buprenorphine, methadone, or naltrexone with counseling and behavioral therapies, significantly improving treatment outcomes and reducing overdose risk.

Found 5,839 treatment centers offering medication-assisted treatment (mat) across the United States.

Need Help Finding the Right Treatment?

Browse our directory or call to discuss treatment options.

Call 1(833) 246-3239
12,000+ Centers
SAMHSA Data
Filters:

Showing 20 of 5839 medication-assisted treatment (mat) treatment centers

CADA - Facility Image

CADA

New Orleans, LA

Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Adult men+1 more
CASA Trinity Inc - Facility Image

CASA Trinity Inc

Hornell, NY

Insurance Accepted$$
DetoxificationSubstance use treatment+1 more
Adult men+1 more
CASA Trinity Inc - Facility Image

CASA Trinity Inc

Geneseo, NY

Insurance Accepted$$
DetoxificationSubstance use treatment+1 more
Adolescents+1 more
CBI Encompass Health Services - Facility Image
Insurance Accepted$$
DetoxificationSubstance use treatment+1 more
Clients who have experienced intimate partner violence, domestic violence+1 more
Centerstone of Indiana Inc - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Adult men+1 more
Centerstone of Indiana Inc - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Adult men+1 more
Central Florida Treatment Center - Facility Image
Insurance Accepted$$
Substance use treatment
Pregnant/postpartum women
Central Maine Family Counseling PA - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Active duty military+1 more
Champlain Valley Family Center - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Adolescents+1 more
Chrysalis House Inc - Facility Image

Chrysalis House Inc

Lexington, KY

Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Adult women+1 more
Clackamas Health Centers - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Adolescents+1 more
Clinic 1 - Facility Image

Clinic 1

New York, NY

Insurance Accepted$$
Substance use treatment
Active duty military+1 more
Comm Outreach Network Servs Inc - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Active duty military+1 more
Communities of Recovery Inc - Facility Image
$$
Substance use treatmentTransitional housing, halfway house, or sober home
Adult men+1 more
Compass Health - Facility Image

Compass Health

Nevada, MO

Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Clients with co-occurring mental and substance use disorders
Conewago Place - Facility Image

Conewago Place

Hummelstown, PA

Insurance Accepted$$
Substance use treatment
Adult men+1 more
Copes Outpatient - Facility Image

Copes Outpatient

La Grande, OR

Insurance Accepted$$
Substance use treatmentTransitional housing, halfway house, or sober home
Adult men+1 more
Counseling Associates Inc - Facility Image
Insurance Accepted$$
Substance use treatmentTreatment for co-occurring substance use plus either serious mental health illness in adults/serious emotional disturbance in children
Criminal justice (other than DUI/DWI)/Forensic clients
Crossroads Recovery Center - Facility Image
Insurance Accepted$$
Substance use treatment
Delphi Rise - Facility Image

Delphi Rise

Rochester, NY

Insurance Accepted$$
Substance use treatment
Adult women

About Medication-Assisted Treatment (MAT)

Medication-Assisted Treatment represents a significant advancement in addiction medicine, dramatically improving outcomes for opioid and alcohol use disorders. At Penn Spine and Rehab, we connect you with MAT providers who combine medication with comprehensive behavioral treatment.

FDA-Approved Medications

For opioid addiction:

  • Buprenorphine (Suboxone, Subutex): Reduces cravings and withdrawal symptoms
  • Methadone: Prevents withdrawal and reduces cravings in supervised settings
  • Naltrexone (Vivitrol): Blocks opioid effects and reduces cravings

For alcohol addiction:

  • Naltrexone: Reduces cravings and the rewarding effects of alcohol
  • Acamprosate (Campral): Helps maintain abstinence after detox
  • Disulfiram (Antabuse): Creates unpleasant effects if alcohol is consumed

MAT Is Not "Replacing One Drug with Another"

A common misconception is that MAT simply substitutes one addiction for another. In reality, MAT medications stabilize brain chemistry, allowing individuals to engage in therapy, maintain employment, and rebuild their lives while reducing overdose risk and relapse rates.

Finding MAT Providers

MAT is available in various settings including outpatient clinics, intensive outpatient programs, and residential treatment centers. Look for programs that combine medication with behavioral therapy for the best outcomes.