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Depression Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Depression treatment within addiction recovery takes an integrated approach to address both conditions simultaneously. Evidence-based therapies like CBT and DBT, medication management when appropriate, and holistic wellness practices help individuals manage depressive symptoms while building a strong foundation for lasting sobriety.

Found 8,160 rehab centers specializing in depression across the United States.

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Showing 20 of 8160 depression rehab centers

Central Peninsula General Hospital
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Central Peninsula General Hospital

Soldotna, AK

Central Peninsula General Hospital, situated in Soldotna, AK, provides a wide array of rehabilitation services designed for those on the path to recovery from substance use disorders. This facility offers various programs, including detoxification, intensive outpatient treatment, and long-term residential care, tailored for both adults and young adults. Furthermore, it has specialized programs aimed at active duty military members and offers dedicated services for adult men and women. The center employs effective methods such as 12-step facilitation and anger management to support clients in their recovery journey. In addition to these services, transitional housing and outpatient care are available, ensuring personalized attention for both male and female clients. Central Peninsula General Hospital is distinguished by its commitment to high-quality care, devoted to helping individuals attain long-term sobriety.

BestCare Treatment Services
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BestCare Treatment Services

Prineville, OR

BestCare Treatment Services, located in Prineville, OR, provides extensive substance use treatment for both adults and children who are dealing with serious mental health issues or emotional disturbances. The center offers a range of options, including outpatient services as well as methadone/buprenorphine and naltrexone treatments. They also incorporate various therapeutic approaches such as 12-step facilitation, anger management, and brief interventions. Tailored programs are available specifically for active duty military personnel, adolescents, and adult men, ensuring that BestCare meets the needs of individuals across different age groups and genders. Renowned for its personalized care and dedication to the recovery process, the facility prioritizes delivering high-quality treatment to those facing challenges related to addiction and mental health.

Reed Behavioral Health
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Reed Behavioral Health

Wayzata, MN

Reed Behavioral Health, situated in Wayzata, MN, provides targeted treatment for both substance use and co-occurring disorders, catering to adults and children alike. Their diverse offerings encompass intensive outpatient, outpatient, and regular outpatient programs. By utilizing evidence-based methods, including cognitive behavioral therapy, motivational interviewing, and contingency management, the center delivers personalized care for adult men, adult women, and those who have faced trauma. Committed to supporting individuals on their path to recovery, Reed Behavioral Health serves adults and young adults of all genders, ensuring they receive the quality care they need to navigate addiction and mental health hurdles.

Coras Wellness and Behavioral Health
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Coras Wellness and Behavioral Health

Millsboro, DE

Coras Wellness and Behavioral Health, located in Millsboro, DE, provides specialized treatment for substance use and co-occurring disorders, catering to both adults and children. The center features intensive outpatient and outpatient programs, which include methadone/buprenorphine treatments. In addition, they offer services like 12-step facilitation, anger management, and brief intervention. This facility is designed to serve both adult men and women, as well as clients who have faced trauma, ensuring that each group receives tailored programs. By supporting adults and young adults of all genders, Coras Wellness and Behavioral Health is dedicated to delivering high-quality care and personalized treatment plans that promote lasting recovery and mental well-being.

Exponents Inc
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Exponents Inc

New York, NY

Located in New York, NY, Exponents Inc offers a wide range of substance use treatment options, including intensive outpatient programs, standard outpatient care, and specialized outpatient treatments such as methadone, buprenorphine, or naltrexone. Their services incorporate crucial elements like anger management, brief interventions, and cognitive behavioral therapy, all aimed at meeting each person’s unique needs. This facility stands out for its specialized programs designed for active duty military personnel, as well as adult men and women, making it a welcoming place for various groups. Whether you're an adult or a young adult, Exponents Inc prioritizes individualized treatment plans and evidence-based practices. If you’re looking for customized addiction support in a nurturing environment, this center could be an excellent choice for you.

List Psychological Services PLC
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List Psychological Services PLC

Bay City, MI

List Psychological Services PLC, located in Bay City, MI, provides outpatient substance use treatment for both adults and children dealing with co-occurring mental health challenges. Their offerings include anger management, cognitive behavioral therapy, and brief intervention services. This facility particularly focuses on clients who have faced trauma, pregnant and postpartum women, as well as those involved in the criminal justice system. Catering to adults and seniors of all genders, List Psychological Services PLC is committed to delivering high-quality, personalized treatment. If you’re looking for comprehensive rehabilitation services in a supportive atmosphere, this center is dedicated to guiding you towards lasting recovery.

Mohave Mental Health Clinic Inc
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Mohave Mental Health Clinic Inc

Lake Havasu City, AZ

Situated in Lake Havasu City, AZ, Mohave Mental Health Clinic Inc provides outpatient services for substance use treatment. The clinic specializes in addressing co-occurring substance use disorders alongside significant mental health challenges in adults, and it also supports children facing severe emotional disturbances. The center employs a range of evidence-based techniques to deliver regular outpatient care, including anger management, brief interventions, and cognitive behavioral therapy. Additionally, there are tailored programs aimed at adolescents and individuals who have encountered intimate partner violence, domestic violence, or sexual abuse. This facility is dedicated to serving a diverse clientele, including adults, seniors, and young adults, regardless of gender. You can expect empathetic and effective care at Mohave Mental Health Clinic Inc.

Coshocton Cnty Drug/Alc Council Inc
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Coshocton Cnty Drug/Alc Council Inc

Coshocton, OH

Located in Coshocton, OH, Coshocton Cnty Drug/Alc Council Inc offers a wide range of services for substance use treatment. In addition to providing transitional housing and sober living options, this facility addresses co-occurring substance use disorders and mental health issues. The center has specialized programs designed for adolescents, trauma survivors, and individuals involved with the criminal justice system, allowing it to meet various needs effectively. Treatment formats include intensive outpatient programs as well as outpatient therapy with methadone and buprenorphine. By utilizing methods like 12-step facilitation, cognitive behavioral therapy, and anger management, the center ensures that adults and seniors of all genders receive personalized care as they work towards recovery.

Choices Counseling Center
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Choices Counseling Center

Roseville, MI

Choices Counseling Center, situated in Roseville, MI, provides outpatient substance use treatment for both adults and young adults. The center emphasizes a range of approaches, including 12-step facilitation, brief interventions, and cognitive behavioral therapy, ensuring that care is comprehensive and tailored to each individual's requirements. This facility has specific programs designed for active duty military personnel, as well as for adult men and women. Understanding the significance of gender-specific and age-appropriate methods, Choices Counseling Center is committed to delivering high-quality, evidence-based treatment for all clients. If you're seeking personalized support to tackle addiction and want a program that fits your unique situation, this center is here to guide you on your recovery journey.

Livengrin
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Livengrin

Fairless Hills, PA

Situated in Fairless Hills, PA, Livengrin specializes in offering a wide range of substance use treatment options for both adults and young adults. The center features intensive outpatient treatment, standard outpatient services, and outpatient day treatment/partial hospitalization. Livengrin employs a comprehensive approach that includes techniques like 12-step facilitation, anger management, and brief interventions. To meet the varying needs of its clients, the facility also provides specialized programs for active duty military personnel, as well as separate services for adult men and women. By offering gender-specific care, Livengrin ensures that every individual receives the personalized support they need. With its commitment to high-quality care and innovative programs, Livengrin stands out as a leading choice for those looking for effective addiction treatment in a nurturing setting.

Valley Healthcare System
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Valley Healthcare System

Kingwood, WV

Located in Kingwood, WV, Valley Healthcare System provides outpatient substance use treatment designed specifically for adults dealing with co-occurring mental health disorders and children grappling with serious emotional issues. This facility offers targeted programs for individuals facing the dual challenges of mental health and substance use. Their treatment methods incorporate anger management strategies, brief intervention sessions, and cognitive behavioral therapy to help clients effectively navigate their recovery. The range of services includes outpatient treatment with methadone, buprenorphine, or naltrexone, in addition to standard outpatient care. Valley Healthcare System serves both men and women from various age groups, ensuring a high standard of care that emphasizes holistic healing.

FourPoints Health
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FourPoints Health

Richfield, UT

Located in Richfield, UT, FourPoints Health provides targeted substance use treatment options, including intensive outpatient, outpatient, and programs featuring methadone/buprenorphine or naltrexone. This facility employs various therapeutic approaches, such as 12-step facilitation, brief intervention, and cognitive behavioral therapy, making it suitable for adults and seniors of all genders. Moreover, specialized programs are designed for those who have experienced intimate partner violence, domestic violence, or trauma. Committed to delivering quality care, FourPoints Health fosters a welcoming environment for individuals on the path to recovery from addiction.

New Hope International Csl Servs LLC
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New Hope International Csl Servs LLC

Louisville, KY

Located in Louisville, KY, New Hope International Csl Servs LLC specializes in outpatient treatment for substance use, serving adults, children, and adolescents alike. The center offers regular outpatient services that emphasize brief interventions, cognitive behavioral therapy, and motivational interviewing. With a distinctive focus on individual needs, this facility accommodates both male and female clients, ensuring each person receives personalized care. Their dedication to providing high-quality treatment and customized programs positions them as an essential resource for anyone in the Louisville community looking for effective addiction rehabilitation services.

Groups Recover Together
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Groups Recover Together

Marion, IN

Located in Marion, IN, Groups Recover Together provides outpatient treatment for substance use, prioritizing a personalized approach to care. The center specializes in offering outpatient services with methadone, buprenorphine, or naltrexone, alongside relapse prevention strategies, substance use disorder counseling, and telemedicine/telehealth therapy. Catering to adults and young adults of all genders, this facility is dedicated to creating individualized recovery plans. With a strong commitment to high-quality care, Groups Recover Together distinguishes itself through its specialized programs and extensive range of services, making it an essential resource for those seeking effective and compassionate addiction treatment in Marion, IN.

WTCR Odessa
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WTCR Odessa

Odessa, TX

WTCR Odessa, situated in Odessa, TX, is dedicated to providing outpatient services for addiction treatment with a primary focus on detoxification and substance use therapies. This facility offers outpatient detox programs alongside treatment options like methadone, buprenorphine, or naltrexone for both adults and young adults, regardless of gender. To ensure a holistic approach to care, WTCR Odessa employs evidence-based methods, including 12-step facilitation, anger management, and brief interventions. They also recognize the unique challenges faced by pregnant and postpartum women, offering specialized programs to meet these specific treatment needs. With a commitment to high-quality care and personalized support, WTCR Odessa is a reliable resource for those in search of effective and empathetic addiction treatment services.

Safe Refuge
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Safe Refuge

Long Beach, CA

Situated in Long Beach, CA, Safe Refuge provides a wide array of substance use treatment services designed for both adults and young adults. This facility is equipped to deliver specialized care to those grappling with co-occurring substance use and significant mental health issues. With options for long-term residential, short-term residential, and around-the-clock residential programs, Safe Refuge customizes its treatment plans to meet the unique needs of each person. The center utilizes evidence-based methods such as 12-step facilitation, anger management, and cognitive behavioral therapy. Additionally, Safe Refuge offers specialized programs for active duty military members, as well as separate services tailored for adult men and women. Committed to delivering high-quality care, this facility ensures a supportive atmosphere with gender-specific treatment, fostering an effective environment for recovery.

A New Hope Counseling LLC
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A New Hope Counseling LLC

Colorado Springs, CO

A New Hope Counseling LLC, situated in Colorado Springs, CO, provides a wide range of substance use treatment programs designed for adults and seniors. The facility emphasizes intensive outpatient treatment, alongside outpatient and regular outpatient options, ensuring that clients receive specialized care. Their services include anger management, brief intervention, and cognitive behavioral therapy, all aimed at fostering recovery. Notably, the center offers unique programs specifically designed for active duty military personnel, adolescents, and adult men, creating a space that caters to diverse needs. With an inclusive approach, A New Hope Counseling LLC welcomes both male and female clients, promoting a supportive atmosphere for everyone. What truly sets this facility apart is its personalized treatment plans and dedication to high-quality care, making it an excellent choice for individuals seeking effective addiction rehabilitation services.

Family Health Centers of San Diego Inc
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Family Health Centers of San Diego Inc

Imperial Beach, CA

Situated in Imperial Beach, CA, Family Health Centers of San Diego Inc provides a wide array of substance use treatment services tailored for both adults and young adults. The center takes a holistic approach, particularly addressing cases where individuals face both substance use and mental health challenges. They offer intensive outpatient and outpatient programs, which include treatments like methadone/buprenorphine. The facility relies on evidence-based methods such as cognitive behavioral therapy and contingency management to meet the diverse needs of its clients. Special attention is given to active duty military personnel, as well as adult men and women, ensuring that care is both gender-specific and age-appropriate. Family Health Centers of San Diego Inc is dedicated to delivering high-quality treatment for individuals who are on the journey to recovery from addiction.

Trillium Place
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Trillium Place

Pekin, IL

Trillium Place, located in Pekin, IL, offers an extensive array of treatment programs for substance use and co-occurring mental health issues. Their services include intensive outpatient, outpatient, and regular outpatient options designed for both adults and children/adolescents. With an emphasis on anger management, brief interventions, and cognitive behavioral therapy, Trillium Place guarantees personalized care for every individual. The facility particularly specializes in adolescent care, welcoming both male and female clients. Recognized for its high-quality services and tailored programs, Trillium Place stands as a source of hope for anyone pursuing effective and compassionate rehabilitation in Illinois.

Community Assessment and Trt Servs
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Community Assessment and Trt Servs

Cleveland, OH

Community Assessment and Treatment Services, located in Cleveland, OH, delivers a wide range of substance use treatment options for adults grappling with serious mental health conditions. They offer intensive outpatient services, outpatient programs, as well as treatments involving methadone, buprenorphine, or naltrexone. The center personalizes its approach by incorporating 12-step facilitation, anger management, and cognitive behavioral therapy to best suit the unique needs of each individual. Additionally, they have specialized programs designed for adult men, adult women, and those who have faced intimate partner violence. Serving adults and young adults of every gender, this facility is dedicated to providing compassionate care and support for individuals on their path to recovery from both addiction and mental health issues.

About Depression Treatment

Depression and substance use often occur together, with each condition potentially worsening the other. At Penn Spine and Rehab, we help individuals find treatment programs that address both depression and addiction simultaneously for the best possible outcomes.

The Connection Between Depression and Addiction

Many people with depression turn to alcohol or drugs to cope with painful feelings, while substance use itself can cause or worsen depressive symptoms. This complex relationship requires integrated treatment that addresses both conditions.

Signs of co-occurring depression and substance use include:

  • Persistent feelings of sadness, emptiness, or hopelessness
  • Loss of interest in previously enjoyed activities
  • Using substances to cope with difficult emotions
  • Worsening depression despite substance use
  • Difficulty functioning at work, school, or in relationships

Integrated Treatment Approaches

Dual diagnosis treatment programs offer comprehensive care including:

Finding the Right Program

Look for treatment centers with psychiatrists and mental health professionals on staff, not just addiction counselors. Residential programs often provide the intensive support needed to stabilize both conditions, while ongoing outpatient care maintains progress.

Causes & Risk Factors for Depression

Depression develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • Neurochemical overlap — both depression and addiction involve serotonin and dopamine dysregulation
  • Self-medication — using substances to numb emotional pain, hopelessness, or fatigue
  • Substance-induced depression — chronic alcohol or drug use depletes mood-regulating neurotransmitters
  • Genetic predisposition — shared hereditary risk factors for both conditions
  • Childhood trauma and adverse experiences
  • Chronic stress, grief, loss, or major life changes
  • Social isolation — both depression and addiction worsen with loneliness

Depression Statistics

21M

US adults had at least one major depressive episode in 2021

Source: NIMH

33%

Of people with major depression also have a substance use disorder

Source: JAMA

63%

Of people with alcohol dependence have a history of depression

Source: NIAAA

2x

People with depression are twice as likely to develop addiction

Source: NIDA

48K+

Suicides in the US in 2021 — substance use is a major risk factor

Source: CDC

40%

Improvement in addiction outcomes when depression is treated concurrently

Source: SAMHSA

What to Expect in Depression Treatment

1

Comprehensive Assessment (Days 1-3)

Psychiatric evaluation and substance use assessment. PHQ-9 depression screening. Determine if depression is independent or substance-induced. Create integrated treatment plan.

2

Detox & Psychiatric Stabilization (Days 3-10)

Safe withdrawal management. Begin antidepressant medication if indicated (SSRIs may take 2-4 weeks for full effect). Monitor suicidal ideation. Comfort care and sleep hygiene.

3

Active Integrated Treatment (Weeks 2-8)

CBT targeting both depressive thinking patterns and addiction triggers. Behavioral activation to counter depression-related withdrawal. Group therapy. Medication optimization.

4

Skill Building & Recovery Planning (Weeks 8-12)

Relapse prevention for both conditions. Healthy routine development (exercise, sleep, nutrition). Family therapy. Building social support network beyond substances.

5

Aftercare & Maintenance (Ongoing)

Continued antidepressant management with psychiatrist. Step-down to outpatient therapy. Peer support groups. Ongoing monitoring of mood and cravings. Safety planning.

Frequently Asked Questions About Depression Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Depression & Addiction Treatment | Penn Spine and Rehab