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Depression Rehab Centers

Written by Penn Spine and Rehab Editorial Team, CADC, LPC
Medically reviewed by Dr. James Mitchell, MD, FASAM
Last updated: March 27, 2026

Depression treatment within addiction recovery takes an integrated approach to address both conditions simultaneously. Evidence-based therapies like CBT and DBT, medication management when appropriate, and holistic wellness practices help individuals manage depressive symptoms while building a strong foundation for lasting sobriety.

Found 8,160 rehab centers specializing in depression across the United States.

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Showing 20 of 8160 depression rehab centers

BrightView Health
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BrightView Health

Columbus, OH

Located in Columbus, OH, BrightView Health provides a full range of addiction treatment services aimed at both adults and young adults. The facility specializes in intensive outpatient treatment, outpatient detox, and various outpatient programs. By incorporating techniques like anger management, brief intervention, and cognitive behavioral therapy, this center customizes its treatment plans to meet each individual's needs. What makes BrightView Health particularly notable is its dedicated programs for LGBTQ individuals and women who are pregnant or postpartum. Committed to delivering high-quality care, the center welcomes both male and female clients, fostering a supportive and inclusive atmosphere for everyone on their journey to recovery from substance use.

SOAP MAT LLC
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SOAP MAT LLC

Oceanside, CA

Situated in Oceanside, CA, SOAP MAT LLC provides a wide range of outpatient rehabilitation services for both adults and children/adolescents facing challenges related to substance use disorders and co-occurring mental health issues. The facility features tailored treatment programs designed specifically for active duty military personnel, adolescents, and adult men, ensuring that each individual receives personalized care. Emphasizing evidence-based methods, such as cognitive behavioral therapy and anger management, clients benefit from high-quality support in a nurturing setting. With outpatient detoxification services and options for methadone and buprenorphine treatment, SOAP MAT LLC addresses a variety of needs. Committed to fostering enduring recovery and holistic wellness, this center welcomes both male and female clients.

Arise Recovery Centers
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Arise Recovery Centers

Dallas, TX

Located in Dallas, TX, Arise Recovery Centers delivers a wide range of substance use treatment options, including intensive outpatient, outpatient, and regular outpatient programs. Their specialized services incorporate 12-step facilitation, anger management, and brief intervention strategies. Notably, they offer tailored programs for adult men, adult women, and individuals who have faced intimate partner or domestic violence. This center is dedicated to helping adults and young adults of all genders, emphasizing personalized treatment plans and a commitment to high-quality care as clients work towards their recovery goals.

North Texas Addiction Counseling and
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North Texas Addiction Counseling and

Fort Worth, TX

North Texas Addiction Counseling, situated in Fort Worth, TX, provides outpatient treatment for substance use with tailored programs designed for adult men, adult women, and individuals who have faced intimate partner or domestic violence. Among the treatment options offered are anger management, brief intervention, and cognitive behavioral therapy. The facility also offers outpatient services for methadone, buprenorphine, or naltrexone for those who require it. Catering to both adults and young adults of all genders, this center is dedicated to delivering high-quality care through evidence-based methods that support individuals on their path to recovery.

Savida Health
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Savida Health

Saint Albans, VT

Located in Saint Albans, VT, Savida Health specializes in outpatient treatment for substance use issues alongside serious mental health conditions in adults, as well as addressing significant emotional disturbances in children. The facility offers a variety of outpatient services, including treatment options with methadone, buprenorphine, or naltrexone, in addition to standard outpatient care. Their methodology incorporates anger management, brief interventions, and cognitive behavioral therapy. Savida Health also has specialized programs designed for adult men, women, and those who have experienced trauma, ensuring comprehensive support. By catering to both men and women across adult and young adult demographics, Savida Health is dedicated to providing quality care that meets individual needs, fostering an environment of healing and recovery with empathy and respect.

Northeast Kingdom Human Services Inc
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Northeast Kingdom Human Services Inc

Newport, VT

Situated in Newport, VT, Northeast Kingdom Human Services Inc delivers an extensive array of substance use treatment options for both adults and children struggling with significant mental health issues. The center offers a variety of services, including intensive outpatient treatment, outpatient care, and targeted methadone/buprenorphine or naltrexone therapies. Emphasizing evidence-based methods such as cognitive behavioral therapy and anger management, this facility supports adult men, women, and adolescents alike. They provide customized programs designed to meet the unique needs of each gender, ensuring personalized care. With a focus on adults and seniors, Northeast Kingdom Human Services Inc is recognized for its dedication to high-quality care and effective treatment solutions.

SaVida Health
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SaVida Health

Newark, DE

Located in Newark, DE, SaVida Health provides outpatient substance use treatment for both adults and young adults who are facing serious mental health issues or emotional challenges. The center features specialized programs designed for active duty military personnel, as well as adult men and women. Treatment options include outpatient methadone, buprenorphine, or naltrexone. SaVida Health prides itself on using evidence-based methods such as brief intervention, contingency management, and relapse prevention to deliver well-rounded care. Committed to quality and individualized treatment, the center is dedicated to offering personalized support to help clients of all genders on their journey to recovery from addiction.

Catholic Charities of Utica/Rome
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Catholic Charities of Utica/Rome

Utica, NY

Situated in Utica, NY, Catholic Charities of Utica/Rome provides a nurturing environment for adult women seeking long-term residential treatment for substance use issues. This facility offers a variety of options including transitional housing, a halfway house, and sober living homes, specifically designed for clients facing both mental health and substance use disorders. The program employs evidence-based methods, incorporating techniques like anger management, cognitive behavioral therapy, and motivational interviewing to tailor support to each individual's unique needs. With a strong emphasis on assisting those who have experienced trauma, the center serves adults, seniors, and young adults in a gender-specific environment. Catholic Charities of Utica/Rome is committed to delivering high-quality rehabilitation services to promote enduring recovery.

BAART Behavioral Health Services Inc
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BAART Behavioral Health Services Inc

Fresno, CA

BAART Behavioral Health Services Inc, located in Fresno, CA, provides outpatient detoxification specifically designed for adults and young adults who are looking to address their addiction. The center employs evidence-based approaches, including cognitive behavioral therapy, motivational interviewing, and strategies geared toward preventing relapse. They offer specialized programs tailored for adult men, adult women, and LGBTQ individuals, ensuring that everyone receives the care that meets their unique needs. With a strong emphasis on personalized treatment plans, this facility is dedicated to supporting both male and female clients as they navigate their recovery journey. BAART Behavioral Health Services Inc is committed to delivering high-quality care to help individuals achieve lasting sobriety and improved overall well-being.

Assoc for the Adv of Mexican Amer Inc
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Assoc for the Adv of Mexican Amer Inc

Houston, TX

The Association for the Advancement of Mexican Americans (AAMA) in Houston, TX, provides a range of substance use treatment options. Their offerings include intensive outpatient, outpatient, and regular outpatient programs. With an emphasis on anger management, brief intervention, and cognitive behavioral therapy, the facility specializes in supporting adolescents, survivors of sexual abuse, and individuals who have faced trauma. Catering to adults, children, adolescents, and young adults of all genders, AAMA is dedicated to developing personalized treatment plans tailored to the unique needs of each client. Committed to delivering high-quality care, this center stands out as an excellent choice for those in search of comprehensive and effective addiction treatment services.

Providence Little Company of
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Providence Little Company of

San Pedro, CA

Providence Little Company of San Pedro, CA, delivers a wide range of addiction treatment services designed for both adults and young adults. This facility specializes in hospital inpatient detoxification and treatment for substance use disorders, along with addressing co-occurring mental health issues. Their program uses a blend of strategies, including 12-step facilitation, anger management, and brief interventions, to meet the specific needs of each individual. The center offers specialized programs tailored for active duty military members, as well as distinct options for adult men and women, serving a variety of populations. Patients can look forward to receiving top-notch care that is customized to fit their unique circumstances, all within a nurturing environment that promotes recovery.

Shasta County Health and Human Servs
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Shasta County Health and Human Servs

Redding, CA

Situated in Redding, CA, Shasta County Health and Human Services provides a wide array of substance use treatment options specifically designed for adult women who have faced trauma, intimate partner violence, or domestic violence. This facility offers various treatment formats, including intensive outpatient, outpatient, and regular outpatient programs. It emphasizes evidence-based methods, incorporating techniques like anger management, cognitive behavioral therapy, and the Matrix Model. By focusing on adult, senior, and young adult females, this center is committed to delivering personalized care and support for those on their journey to recovering from substance use disorders.

CPC Integrated Health
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CPC Integrated Health

Freehold, NJ

CPC Integrated Health, situated in Freehold, NJ, specializes in offering a broad spectrum of substance use treatment as well as targeted care for individuals dealing with serious mental health challenges. The facility provides various options, including intensive outpatient treatment, standard outpatient services, and outpatient treatments with methadone, buprenorphine, or naltrexone. Their therapeutic methods encompass anger management, brief intervention, and cognitive behavioral therapy. With programs designed specifically for adolescents, adult men, and adult women, CPC Integrated Health is committed to meeting the diverse needs of its clients. They proudly serve both adults and children/adolescents of all genders, ensuring that everyone receives the quality care and support they need on their journey to recovery.

New Horizons Treatment Center
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New Horizons Treatment Center

Rome, GA

New Horizons Treatment Center, situated in Rome, GA, offers a wide array of outpatient services aimed at detoxification and substance use treatment. Their menu of services includes outpatient detox, as well as treatments utilizing methadone, buprenorphine, or naltrexone. They also adopt various methods such as 12-step facilitation, anger management, and brief interventions. This center specifically supports adult women and clients who have faced challenges like intimate partner violence, domestic violence, and sexual abuse. With a commitment to serving adults and young adults of all genders, New Horizons is dedicated to providing personalized care that addresses each individual's distinct needs.

Strong Memorial Hospital
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Strong Memorial Hospital

Rochester, NY

Situated in Rochester, NY, Strong Memorial Hospital delivers an extensive array of outpatient services designed for those on the path to recovery from substance use disorders. The center features specialized treatment programs for adults who are dealing with both mental health challenges and for children facing emotional disturbances. Emphasizing techniques such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies, the facility customizes its approach to cater to the unique needs of each individual. It also offers dedicated programs specifically for adolescents, adult men, and adult women to ensure focused care. Committed to serving adults and young adults of all genders, Strong Memorial Hospital strives to provide top-notch, evidence-based care that supports sustainable recovery.

Phoenix House Florida
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Phoenix House Florida

Tampa, FL

Located in Tampa, FL, Phoenix House Florida delivers a wide range of substance use treatment options tailored for both adults and children dealing with co-occurring mental health disorders. The facility features intensive outpatient and outpatient programs, incorporating treatments like methadone/buprenorphine and naltrexone. With specialized programs designed for adolescents, as well as adult men and women, the center is equipped to serve a variety of demographic groups. Phoenix House Florida employs a combination of 12-step facilitation, anger management strategies, and brief intervention methods to provide personalized care for each client. Committed to helping individuals navigate their journey towards recovery, the center serves both male and female clientele, placing a strong emphasis on delivering high-quality treatment for those facing addiction and mental health challenges.

Pillars of Wellness
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Pillars of Wellness

Merrillville, IN

Pillars of Wellness, located in Merrillville, IN, provides outpatient treatment for substance use, emphasizing techniques like anger management, brief interventions, and cognitive behavioral therapy. The facility caters to various groups, including adolescents, adult men, and adult women, ensuring that each program is tailored to meet the specific needs of its clients. With a focus on serving adults and seniors of all genders, Pillars of Wellness is dedicated to delivering quality care. Their goal is to assist individuals on their recovery journey by offering a range of treatment options in a supportive atmosphere. If you’re looking for effective and personalized addiction treatment, this facility might just be the perfect place for you.

CORE Medical Clinic Inc
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CORE Medical Clinic Inc

Sacramento, CA

Located in Sacramento, CA, CORE Medical Clinic Inc specializes in outpatient substance use treatment and employs evidence-based methods such as cognitive behavioral therapy, motivational interviewing, and relapse prevention strategies. This clinic serves a diverse clientele, including adults, children, adolescents, and pregnant or postpartum women. They offer tailored programs specifically designed for individuals facing co-occurring mental health and substance use disorders, as well as those who have been involved with the criminal justice system. CORE Medical Clinic accommodates both male and female clients, providing outpatient treatment options that include methadone, buprenorphine, or naltrexone as part of their regular care. With a strong commitment to quality and individualized treatment plans, CORE Medical Clinic Inc strives to assist individuals on their journey to recovery from addiction.

Commitment House LLC
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Commitment House LLC

Elizabethtown, KY

Commitment House LLC, located in Elizabethtown, KY, specializes in addiction treatment services specifically designed for adult women facing substance use issues alongside serious mental health conditions. The facility offers a range of options, including intensive outpatient, outpatient, and day treatment. They employ evidence-based methods such as 12-step facilitation, brief intervention, and cognitive behavioral therapy in their programs. Catering to women from various age groups—adults, seniors, and young adults—the center is dedicated to providing high-quality care. Their focus on personalized treatment plans ensures that each individual receives the comprehensive support they need for successful rehabilitation.

Odyssey House Inc
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Odyssey House Inc

Salt Lake City, UT

Odyssey House Inc, located in Salt Lake City, UT, specializes in providing thorough substance use treatment along with targeted care for adults dealing with serious mental health challenges or for children experiencing emotional issues. The center offers a range of treatment options, including long-term, 24-hour residential stays, as well as shorter-term programs. Their individualized care plans incorporate various approaches such as 12-step facilitation, anger management, and brief interventions to meet each client’s unique needs. Notably, there are special programs tailored for active duty military personnel, adult men, and women. Odyssey House Inc is dedicated to serving adults and young adults of all genders, ensuring high-quality, gender-specific care that fosters lasting recovery.

About Depression Treatment

Depression and substance use often occur together, with each condition potentially worsening the other. At Penn Spine and Rehab, we help individuals find treatment programs that address both depression and addiction simultaneously for the best possible outcomes.

The Connection Between Depression and Addiction

Many people with depression turn to alcohol or drugs to cope with painful feelings, while substance use itself can cause or worsen depressive symptoms. This complex relationship requires integrated treatment that addresses both conditions.

Signs of co-occurring depression and substance use include:

  • Persistent feelings of sadness, emptiness, or hopelessness
  • Loss of interest in previously enjoyed activities
  • Using substances to cope with difficult emotions
  • Worsening depression despite substance use
  • Difficulty functioning at work, school, or in relationships

Integrated Treatment Approaches

Dual diagnosis treatment programs offer comprehensive care including:

Finding the Right Program

Look for treatment centers with psychiatrists and mental health professionals on staff, not just addiction counselors. Residential programs often provide the intensive support needed to stabilize both conditions, while ongoing outpatient care maintains progress.

Causes & Risk Factors for Depression

Depression develops through a combination of genetic, environmental, and psychological factors. Understanding these risk factors can help identify who may be vulnerable and support early intervention.

  • Neurochemical overlap — both depression and addiction involve serotonin and dopamine dysregulation
  • Self-medication — using substances to numb emotional pain, hopelessness, or fatigue
  • Substance-induced depression — chronic alcohol or drug use depletes mood-regulating neurotransmitters
  • Genetic predisposition — shared hereditary risk factors for both conditions
  • Childhood trauma and adverse experiences
  • Chronic stress, grief, loss, or major life changes
  • Social isolation — both depression and addiction worsen with loneliness

Depression Statistics

21M

US adults had at least one major depressive episode in 2021

Source: NIMH

33%

Of people with major depression also have a substance use disorder

Source: JAMA

63%

Of people with alcohol dependence have a history of depression

Source: NIAAA

2x

People with depression are twice as likely to develop addiction

Source: NIDA

48K+

Suicides in the US in 2021 — substance use is a major risk factor

Source: CDC

40%

Improvement in addiction outcomes when depression is treated concurrently

Source: SAMHSA

What to Expect in Depression Treatment

1

Comprehensive Assessment (Days 1-3)

Psychiatric evaluation and substance use assessment. PHQ-9 depression screening. Determine if depression is independent or substance-induced. Create integrated treatment plan.

2

Detox & Psychiatric Stabilization (Days 3-10)

Safe withdrawal management. Begin antidepressant medication if indicated (SSRIs may take 2-4 weeks for full effect). Monitor suicidal ideation. Comfort care and sleep hygiene.

3

Active Integrated Treatment (Weeks 2-8)

CBT targeting both depressive thinking patterns and addiction triggers. Behavioral activation to counter depression-related withdrawal. Group therapy. Medication optimization.

4

Skill Building & Recovery Planning (Weeks 8-12)

Relapse prevention for both conditions. Healthy routine development (exercise, sleep, nutrition). Family therapy. Building social support network beyond substances.

5

Aftercare & Maintenance (Ongoing)

Continued antidepressant management with psychiatrist. Step-down to outpatient therapy. Peer support groups. Ongoing monitoring of mood and cravings. Safety planning.

Frequently Asked Questions About Depression Treatment

Resources & Sources

The information on this page is based on peer-reviewed research and authoritative health organizations. Always consult a healthcare professional for medical advice.

Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always seek the guidance of a qualified healthcare provider for diagnosis and treatment. If you or someone you know is in crisis, call 911 or the SAMHSA National Helpline at 1-800-662-4357 (free, confidential, 24/7).

Depression & Addiction Treatment | Penn Spine and Rehab